Coumarin derivatives: an updated patent review (2012 – 2014)

Synthesis of aminoalkyl-substituted coumarin derivatives as acetylcholinesterase inhibitors

(2014) Seung Ok Nam et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and biological evaluation of 4-(1,2,3-triazol-1-yl)coumarin derivatives as potential antitumor agents

(2014) Wenjuan Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

IMM-H004, a novel coumarin derivative compound, attenuates the production of inflammatory mediatory mediators in lipopolysaccharide-activated BV2 microglia

(2014) Xiu-Yun Song et al.   BRAIN RESEARCH BULLETIN

Manganese(iii)-mediated direct Csp2–H radical trifluoromethylation of coumarins with sodium trifluoromethanesulfinate

(2014) Xiao-Hui Cao et al.   CHEMICAL COMMUNICATIONS

Synthesis and biological evaluation of coumarin–1,2,3-triazole–dithiocarbamate hybrids as potent LSD1 inhibitors

(2014) Xian-Wei Ye et al.   MedChemComm

Design, synthesis and antitumor activity in vitro of a series of 3-arylcoumarins

(2013) Zhi-hui Liu et al.   CHEMICAL RESEARCH IN CHINESE UNIVERSITIES

Advances in the development of hybrid anticancer drugs

(2013) Sébastien Fortin et al.   Expert Opinion on Drug Discovery

Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation

(2013) G. Vistoli et al.   FREE RADICAL RESEARCH

Synthesis and Antimicrobial Activities of Some Triazole, Thiadiazole, and Oxadiazole Substituted Coumarins

(2013) K. Rajasekhar Reddy et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Substituted 3-Benzylcoumarins as Allosteric MEK1 Inhibitors: Design, Synthesis and Biological Evaluation as Antiviral Agents

(2013) Chao Wang et al.   MOLECULES

IMM-H004, a novel coumarin derivative compound, protects against amyloid beta-induced neurotoxicity through a mitochondrial-dependent pathway

(2013) X.Y. Song et al.   NEUROSCIENCE

Coumarin-based drugs: a patent review (2008 – present)

(2012) Christos Kontogiorgis et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approaches

(2012) Antonella De Luca et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

An Artificial Pathway to 3,4-Dihydroxybenzoic Acid Allows Generation of New Aminocoumarin Antibiotic Recognized by Catechol Transporters of E. coli

(2011) Silke Alt et al.   CHEMISTRY & BIOLOGY

A class of Trp-Trp-AA-OBzl: Synthesis, in vitro anti-proliferation/in vivo anti-tumor evaluation, intercalation-mechanism investigation and 3D QSAR analysis

(2011) Xiaoyi Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs)

(2010) Peter Goettig et al.   BIOCHIMIE

Synthesis and in vitro evaluation of novel coumarin–chalcone hybrids as potential anticancer agents

(2010) Koneni V. Sashidhara et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery and Optimization of Novel 3-Piperazinylcoumarin Antagonist of Chemokine-like Factor 1 with Oral Antiasthma Activity in Mice

(2010) Gang Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis

(2010) Neel R Gandhi et al.   LANCET

Siderophores as drug delivery agents: application of the “Trojan Horse” strategy

(2009) Ute Möllmann et al.   BIOMETALS

Effects of theanine on growth of human lung cancer and leukemia cells as well as migration and invasion of human lung cancer cells

(2009) Qian Liu et al.   CYTOTECHNOLOGY

A study of the antimicrobial activity of selected naturally occurring and synthetic coumarins

(2009) T. Smyth et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Biological Activities of Novel Gyrase Inhibitors of the Aminocoumarin Class

(2008) C. Anderle et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

NVP-BEZ235, a Dual PI3K/mTOR Inhibitor, Prevents PI3K Signaling and Inhibits the Growth of Cancer Cells with Activating PI3K Mutations

(2008) V. Serra et al.   CANCER RESEARCH

Advanced Glycation End Products (AGEs) and their Involvement in Liver Disease

(2008) Hideyuki Hyogo et al.   CURRENT PHARMACEUTICAL DESIGN