Synthesis and biological evaluation of coumarin–1,2,3-triazole–dithiocarbamate hybrids as potent LSD1 inhibitors

Design, synthesis and antiproliferative activity studies of novel 1,2,3-triazole–dithiocarbamate–urea hybrids

(2013) Ying-Chao Duan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis of novel 1,2,3-triazole-dithiocarbamate hybrids as potential anticancer agents

(2013) Ying-Chao Duan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Triazole–Dithiocarbamate Based Selective Lysine Specific Demethylase 1 (LSD1) Inactivators Inhibit Gastric Cancer Cell Growth, Invasion, and Migration

(2013) Yi-Chao Zheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and evaluation of 3-amino/guanidine substituted phenyl oxazoles as a novel class of LSD1 inhibitors with anti-proliferative properties

(2013) Balakrishna Dulla et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Lysine-Specific Histone Demethylase 1 Inhibitors Control Breast Cancer Proliferation in ERα-Dependent and -Independent Manners

(2012) Julie A. Pollock et al.   ACS Chemical Biology

Over-Expression of LSD1 Promotes Proliferation, Migration and Invasion in Non-Small Cell Lung Cancer

(2012) Tangfeng Lv et al.   PLoS One

Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells

(2011) Qingsong Zhu et al.   AMINO ACIDS

Enantioselective synthesis of tranylcypromine analogues as lysine demethylase (LSD1) inhibitors

(2011) Hanae Benelkebir et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Inhibitors of histone demethylases

(2011) Brian Lohse et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A novel synthesis of 3-aryl coumarins and evaluation of their antioxidant and lipoxygenase inhibitory activity

(2010) Marina Roussaki et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, selective anti-Helicobacter pylori activity, and cytotoxicity of novel N-substituted-2-oxo-2H-1-benzopyran-3-carboxamides

(2010) Franco Chimenti et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Comparative Analysis of Small Molecules and Histone Substrate Analogues as LSD1 Lysine Demethylase Inhibitors

(2010) Jeffrey C. Culhane et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lysine Methylation Regulates E2F1-Induced Cell Death

(2010) Haroula Kontaki et al.   MOLECULAR CELL

Identification of Cell-Active Lysine Specific Demethylase 1-Selective Inhibitors

(2009) Rie Ueda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design, synthesis, and acetylcholinesterase inhibitory activity of novel coumarin analogues

(2008) Xiang Zhou et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Facile synthesis of substituted trans-2-arylcyclopropylamine inhibitors of the human histone demethylase LSD1 and monoamine oxidases A and B

(2008) David M. Gooden et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

(2008) Jing Wang et al.   NATURE GENETICS

Structural insights into hydroxycoumarin-induced apoptosis in U-937 cells

(2007) Maria E. Riveiro et al.   BIOORGANIC & MEDICINAL CHEMISTRY