Novel histamine H4receptor ligands and their potential therapeutic applications: an update
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Title
Novel histamine H4receptor ligands and their potential therapeutic applications: an update
Authors
Keywords
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Journal
EXPERT OPINION ON THERAPEUTIC PATENTS
Volume 24, Issue 11, Pages 1185-1197
Publisher
Informa Healthcare
Online
2014-09-15
DOI
10.1517/13543776.2014.959494
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- (2013) C Ballerini et al. BRITISH JOURNAL OF PHARMACOLOGY
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- (2013) Eriko Suwa et al. EXPERIMENTAL DERMATOLOGY
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- (2013) Christoph P. Czerner et al. INFLAMMATION RESEARCH
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- (2013) Detlef Neumann et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Pleiotropic effect of histamine H4 receptor modulation in the central nervous system
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- Protection of Radiation-Induced Damage to the Hematopoietic System, Small Intestine and Salivary Glands in Rats by JNJ7777120 Compound, a Histamine H4 Ligand
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- The antagonism of histamine H1 and H4 receptors ameliorates chronic allergic dermatitis via anti-pruritic and anti-inflammatory effects in NC/Nga mice
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- Detailed structure–activity relationship of indolecarboxamides as H4 receptor ligands
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- Advantages of histamine H4 receptor antagonist usage with H1 receptor antagonist for the treatment of murine allergic contact dermatitis
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