Anti-infective carbonic anhydrase inhibitors: a patent and literature review

A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules

(2013) Sonia Del Prete et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Carbonic anhydrases: from biomedical applications of the inhibitors and activators to biotechnological use for CO2 capture

(2013) Claudiu T. Supuran   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides

(2012) Daniela Vullo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The first activation study of a bacterial carbonic anhydrase (CA). The thermostable α-CA from Sulfurihydrogenibium yellowstonense YO3AOP1 is highly activated by amino acids and amines

(2012) Daniela Vullo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Anion inhibition studies of an α-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1

(2012) Viviana De Luca et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Anion inhibition studies of the fastest carbonic anhydrase (CA) known, the extremo-CA from the bacterium Sulfurihydrogenibium azorense

(2012) Daniela Vullo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibition of the β-carbonic anhydrases from Mycobacterium tuberculosis with C-cinnamoyl glycosides: Identification of the first inhibitor with anti-mycobacterial activity

(2012) María V. Buchieri et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The extremo-α-carbonic anhydrase (CA) from Sulfurihydrogenibium azorense, the fastest CA known, is highly activated by amino acids and amines

(2012) Atilla Akdemir et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Additional risk factors for infection by multidrug-resistant pathogens in healthcare-associated infection: a large cohort study

(2012) Teresa Cardoso et al.   BMC INFECTIOUS DISEASES

Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?

(2012) Vincenzo Alterio et al.   CHEMICAL REVIEWS

Update on carbonic anhydrase inhibitors: a patent review (2008 – 2011)

(2012) Mayank Aggarwal et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Porphyromonas gingivalis: an invasive and evasive opportunistic oral pathogen

(2012) Nagihan Bostanci et al.   FEMS MICROBIOLOGY LETTERS

Structure-based drug discovery of carbonic anhydrase inhibitors

(2012) Claudiu T. Supuran   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Biochemical properties of a novel and highly thermostable bacterial α-carbonic anhydrase fromSulfurihydrogenibium yellowstonense YO3AOP1

(2012) Clemente Capasso et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Molecular Cloning, Characterization, and Inhibition Studies of a β-Carbonic Anhydrase from Malassezia globosa, a Potential Antidandruff Target

(2012) Kirsty S. Hewitson et al.   JOURNAL OF MEDICINAL CHEMISTRY

DNA Cloning, Characterization, and Inhibition Studies of an α-Carbonic Anhydrase from the Pathogenic Bacterium Vibrio cholerae

(2012) Sonia Del Prete et al.   JOURNAL OF MEDICINAL CHEMISTRY

Reproductive clonality of pathogens: A perspective on pathogenic viruses, bacteria, fungi, and parasitic protozoa

(2012) M. Tibayrenc et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with branched aliphatic/aromatic carboxylates and their derivatives

(2011) Fabrizio Carta et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibition studies with anions and small molecules of two novel β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium

(2011) Daniela Vullo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

EVOLUTIONARY PERSPECTIVES IN A MUTUALISM OF SEPIOLID SQUID AND BIOLUMINESCENT BACTERIA: COMBINED USAGE OF MICROBIAL EXPERIMENTAL EVOLUTION AND TEMPORAL POPULATION GENETICS

(2011) W. Soto et al.   EVOLUTION

Novel therapies for glaucoma: a patent review 2007 – 2011

(2011) Fabrizio Carta et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Structure of a dimeric fungal α-type carbonic anhydrase

(2011) Jose Antonio Cuesta-Seijo et al.   FEBS LETTERS

Carbonic Anhydrases inhibitory effects of new benzenesulfonamides synthesized by using superacid chemistry

(2011) Fei Liu et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

(In)organic anions as carbonic anhydrase inhibitors

(2011) Giuseppina De Simone et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Glycosyl Coumarin Carbonic Anhydrase IX and XII Inhibitors Strongly Attenuate the Growth of Primary Breast Tumors

(2011) Nadia Touisni et al.   JOURNAL OF MEDICINAL CHEMISTRY

Interfering with pH regulation in tumours as a therapeutic strategy

(2011) Dario Neri et al.   NATURE REVIEWS DRUG DISCOVERY

Caterpillars and Fungal Pathogens: Two Co-Occurring Parasites of an Ant-Plant Mutualism

(2011) Olivier Roux et al.   PLoS One

Bacterial Carbonic Anhydrases as Drug Targets: Toward Novel Antibiotics?

(2011) Claudiu T. Supuran   Frontiers in Pharmacology

Inhibition of the β-carbonic anhydrase from Streptococcus pneumoniae by inorganic anions and small molecules: Toward innovative drug design of antiinfectives?

(2010) Peter Burghout et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth

(2010) Pascale Joseph et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors. The β-carbonic anhydrases from the fungal pathogens Cryptococcus neoformans and Candida albicans are strongly inhibited by substituted-phenyl-1H-indole-5-sulfonamides

(2010) Özlen Güzel et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibition studies of a β-carbonic anhydrase from Brucella suis with a series of water soluble glycosyl sulfanilamides

(2010) Daniela Vullo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Carbonic anhydrase inhibitors

(2010) Claudiu T. Supuran   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata

(2010) Anthony Bertucci et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Carbonic Anhydrase Inhibition/Activation: Trip of a Scientist Around the World in the Search of Novel Chemotypes and Drug Targets

(2010) Claudiu T. Supuran   CURRENT PHARMACEUTICAL DESIGN

The β-Carbonic Anhydrases from Mycobacterium tuberculosis as Drug Targets

(2010) Isao Nishimoria et al.   CURRENT PHARMACEUTICAL DESIGN

Cloning, Characterization, and Inhibition Studies of a β-Carbonic Anhydrase fromBrucella suis

(2010) Pascale Joseph et al.   JOURNAL OF MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with aliphatic and aromatic carboxylates

(2009) Alessio Innocenti et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal β-carbonic anhydrase from Candida albicans with sulfonamides

(2009) Alessio Innocenti et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Carbonic anhydrase activators: Activation of the β-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids

(2009) Semra Isik et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Carbonic anhydrase inhibitors. Inhibition of the β-class enzyme from the pathogenic yeast Candida glabrata with anions

(2009) Alessio Innocenti et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active β-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c

(2009) Fabrizio Carta et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Carbonic Anhydrase Inhibitors. Cloning, Characterization, and Inhibition Studies of a New β-Carbonic Anhydrase fromMycobacterium tuberculosis

(2009) Isao Nishimori et al.   JOURNAL OF MEDICINAL CHEMISTRY

Molecular Cloning, Characterization, and Inhibition Studies of the Rv1284 β-Carbonic Anhydrase fromMycobacterium tuberculosiswith Sulfonamides and a Sulfamate

(2009) Tomoko Minakuchi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of Low Nanomolar and Subnanomolar Inhibitors of the Mycobacterial β-Carbonic Anhydrases Rv1284 and Rv3273

(2009) Özlen Güzel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Carbonic anhydrases in fungi

(2009) S. Elleuche et al.   MICROBIOLOGY-SGM

Carbonic anhydrase inhibitors: Inhibition of the β-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates

(2008) Semra Isik et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors. Inhibition of the β-class enzyme from the yeast Saccharomyces cerevisiae with anions

(2008) Semra Isik et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Carbonic anhydrase inhibitors: Inhibition of Plasmodium falciparum carbonic anhydrase with aromatic/heterocyclic sulfonamides—in vitro and in vivo studies

(2008) Jerapan Krungkrai et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Carbonic anhydrase inhibitors: Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with simple anions

(2008) Alessio Innocenti et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Anticonvulsant Sulfonamides/Sulfamates/Sulfamides with Carbonic Anhydrase Inhibitory Activity: Drug Design and Mechanism of Action

(2008) Bernard Masereel et al.   CURRENT PHARMACEUTICAL DESIGN

The Alpha-Carbonic Anhydrase from the Malaria Parasite and its Inhibition

(2008) Jerapan Krungkrai et al.   CURRENT PHARMACEUTICAL DESIGN

Structure and Inhibition of the CO2-Sensing Carbonic Anhydrase Can2 from the Pathogenic Fungus Cryptococcus neoformans

(2008) Christine Schlicker et al.   JOURNAL OF MOLECULAR BIOLOGY

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY