Curcumin and neurodegenerative diseases: a perspective

Curcumin mediates presenilin-1 activity to reduce β-amyloid production in a model of Alzheimer’s disease

(2014) Zhang Xiong et al.   Pharmacological Reports

Conundrum and Therapeutic Potential of Curcumin in Drug Delivery

(2012) Anil Kumar et al.   CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS

The Targets of Curcumin

(2012) Hongyu Zhou et al.   CURRENT DRUG TARGETS

Curcumin: A Potential Neuroprotective Agent in Parkinson's Disease

(2012) R. B. Mythri et al.   CURRENT PHARMACEUTICAL DESIGN

Evaluation of Antidepressant-Like Activity of Novel Water-Soluble Curcumin Formulations and St. John's Wort in Behavioral Paradigms of Despair

(2012) S.K. Kulkarni et al.   PHARMACOLOGY

Curcumin Loaded-PLGA Nanoparticles Conjugated with Tet-1 Peptide for Potential Use in Alzheimer's Disease

(2012) Anila Mathew et al.   PLoS One

The pharmacology of curcumin: is it the degradation products?

(2012) Liang Shen et al.   TRENDS IN MOLECULAR MEDICINE

Natural substances and Alzheimer's disease: From preclinical studies to evidence based medicine

(2011) Cesare Mancuso et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Chronic dietary supplementation with turmeric protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-mediated neurotoxicity in vivo: implications for Parkinson's disease

(2011) Rajeswara Babu Mythri et al.   BRITISH JOURNAL OF NUTRITION

Discovery of curcumin, a component of golden spice, and its miraculous biological activities

(2011) Subash C Gupta et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

α-Synuclein in Parkinson disease and other neurodegenerative disorders

(2011) Michael Eller et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Effects of Flavonoids and other Polyphenols on Inflammation

(2011) R. González et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Modulation of Anxiety Behavior by Intranasally Administered Vaccinia Virus Complement Control Protein and Curcumin in a Mouse Model of Alzheimers Disease

(2011) A. P. Kulkarni et al.   Current Alzheimer Research

Oxidation Chemistry of Catecholamines and Neuronal Degeneration: An Update

(2011) A. Napolitano et al.   CURRENT MEDICINAL CHEMISTRY

Natural Products of Dietary Origin as Lead Compounds in Virtual Screening and Drug Design

(2011) Werner J. Geldenhuys et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Curcumin and Liver Cancer: A Review

(2011) Altaf S. Darvesh et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Curcumin nanoformulations: a future nanomedicine for cancer

(2011) Murali M. Yallapu et al.   DRUG DISCOVERY TODAY

Evaluation of the antioxidant, anti-inflammatory and hepatoprotective properties of vanillin in carbon tetrachloride-treated rats

(2011) Mohamed Makni et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Challenges associated with curcumin therapy in Alzheimer disease

(2011) Abdenour Belkacemi et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Evaluating potential of curcumin loaded solid lipid nanoparticles in aluminium induced behavioural, biochemical and histopathological alterations in mice brain

(2011) Vandita Kakkar et al.   FOOD AND CHEMICAL TOXICOLOGY

Protective effect of curcumin (Curcuma longa) againstd-galactose-induced senescence in mice

(2011) Anil Kumar et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Curcumin and Alzheimer Disease: This Marriage Is Not to Be Performed

(2011) Cesare Mancuso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-Parkinsonian drug discovery from herbal medicines: What have we got from neurotoxic models?

(2011) Ju-Xian Song et al.   JOURNAL OF ETHNOPHARMACOLOGY

Neurovascular dysfunction, inflammation and endothelial activation: Implications for the pathogenesis of Alzheimer's disease

(2011) Paula Grammas   Journal of Neuroinflammation

Curcumin: An Anti-Inflammatory Molecule from a Curry Spice on the Path to Cancer Treatment

(2011) Purusotam Basnet et al.   MOLECULES

Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide

(2011) Mark Taylor et al.   Nanomedicine-Nanotechnology Biology and Medicine

Curcumin protects against A53T alpha-synuclein-induced toxicity in a PC12 inducible cell model for Parkinsonism

(2011) Zhaohui Liu et al.   PHARMACOLOGICAL RESEARCH

Curcumin-decorated nanoliposomes with very high affinity for amyloid-β1-42 peptide

(2010) Spyridon Mourtas et al.   BIOMATERIALS

Curcumin reduces α-synuclein induced cytotoxicity in Parkinson's disease cell model

(2010) Min S Wang et al.   BMC NEUROSCIENCE

Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies

(2010) Jenny Epstein et al.   BRITISH JOURNAL OF NUTRITION

Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals

(2010) Subash C. Gupta et al.   CANCER AND METASTASIS REVIEWS

REVIEW: Curcumin and Alzheimer's Disease

(2010) Tsuyoshi Hamaguchi et al.   CNS Neuroscience & Therapeutics

New Therapeutic Strategy for Parkinsons and Alzheimers Disease

(2010) E. Esposito et al.   CURRENT MEDICINAL CHEMISTRY

Lesson Learned from Nature for the Development of Novel Anti-Cancer Agents: Implication of Isoflavone, Curcumin, and their Synthetic Analogs

(2010) Fazlul H. Sarkar et al.   CURRENT PHARMACEUTICAL DESIGN

Neuroprotective and neurotrophic curcuminoids to treat stroke: a translational perspective

(2010) Paul A Lapchak   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Oxidative stress and Alzheimer’s disease: dietary polyphenols as potential therapeutic agents

(2010) Altaf S Darvesh et al.   Expert Review of Neurotherapeutics

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

An overview of curcumin in neurological disorders

(2010) SK Kulkarni et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

Safety and Pharmacokinetics of a Solid Lipid Curcumin Particle Formulation in Osteosarcoma Patients and Healthy Volunteers

(2010) Vikram S. Gota et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Curcumin Decreases Amyloid-β Peptide Levels by Attenuating the Maturation of Amyloid-β Precursor Protein

(2010) Can Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Why Pleiotropic Interventions are Needed for Alzheimer's Disease

(2010) Sally A. Frautschy et al.   MOLECULAR NEUROBIOLOGY

ApoE3 Mediated Poly(butyl) Cyanoacrylate Nanoparticles Containing Curcumin: Study of Enhanced Activity of Curcumin against Beta Amyloid Induced Cytotoxicity UsingIn VitroCell Culture Model

(2010) Rohit S. Mulik et al.   MOLECULAR PHARMACEUTICS

Nutraceutical Antioxidants as Novel Neuroprotective Agents

(2010) Natalie A. Kelsey et al.   MOLECULES

Revisiting dietary antioxidants, neurodegeneration and dementia

(2010) Lucinda Craggs et al.   NEUROREPORT

Tetrahydrocurcumin confers protection against amyloid β-induced toxicity

(2010) Shilpa Mishra et al.   NEUROREPORT

Curcuminoids enhance memory in an amyloid-infused rat model of Alzheimer's disease

(2010) T. Ahmed et al.   NEUROSCIENCE

The inhibitory effects of different curcuminoids on β-amyloid protein, β-amyloid precursor protein and β-site amyloid precursor protein cleaving enzyme 1 in swAPP HEK293 cells

(2010) Hongying Liu et al.   NEUROSCIENCE LETTERS

Potential protection of curcumin against intracellular amyloid β-induced toxicity in cultured rat prefrontal cortical neurons

(2010) Xiao-Yan Qin et al.   NEUROSCIENCE LETTERS

Curcumin I protects the dopaminergic cell line SH-SY5Y from 6-hydroxydopamine-induced neurotoxicity through attenuation of p53-mediated apoptosis

(2010) Yamaratee Jaisin et al.   NEUROSCIENCE LETTERS

Increased expression of miRNA-146a in Alzheimer's disease transgenic mouse models

(2010) Y.Y. Li et al.   NEUROSCIENCE LETTERS

Plant Polyphenols as Dietary Antioxidants in Human Health and Disease

(2010) Kanti Bhooshan Pandey et al.   Oxidative Medicine and Cellular Longevity

A New Target for Amyloid Beta Toxicity Validated by Standard and High-Throughput Electrophysiology

(2010) Kucku Varghese et al.   PLoS One

Curcumin Prevents Dopaminergic Neuronal Death Through Inhibition of the c-Jun N-Terminal Kinase Pathway

(2010) Song Yu et al.   REJUVENATION RESEARCH

The Role of Polyphenolic Antioxidants in Health, Disease, and Aging

(2010) Mark E. Obrenovich et al.   REJUVENATION RESEARCH

Curcuminoids rescue long-term potentiation impaired by amyloid peptide in rat hippocampal slices

(2010) Touqeer Ahmed et al.   SYNAPSE

Anti-inflammatory activity of natural dietary flavonoids

(2010) Min-Hsiung Pan et al.   Food & Function

2009 Alzheimer's disease facts and figures

(2009)   Alzheimers & Dementia

Phenolic Compounds Prevent Alzheimer’s Pathology through Different Effects on the Amyloid-β Aggregation Pathway

(2009) Tsuyoshi Hamaguchi et al.   AMERICAN JOURNAL OF PATHOLOGY

The effect of curcumin (turmeric) onAlzheimer′s disease: An overview

(2009) Shrikant Mishra et al.   Annals of Indian Academy of Neurology

Curcumin attenuates 6-hydroxydopamine-induced cytotoxicity by anti-oxidation and nuclear factor-kappaB modulation in MES23.5 cells

(2009) Jun Wang et al.   BIOCHEMICAL PHARMACOLOGY

Cancer Prevention and Treatment with Resveratrol: From Rodent Studies to Clinical Trials

(2009) A. Bishayee   Cancer Prevention Research

Optimized Turmeric Extracts have Potent Anti-Amyloidogenic Effects

(2009) R. Shytle et al.   Current Alzheimer Research

Neuroinflammation in Alzheimer's disease: different molecular targets and potential therapeutic agents including curcumin

(2009) Balmiki Ray et al.   CURRENT OPINION IN PHARMACOLOGY

Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer

(2009) J. Shaikh et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Turmeric: The Intriguing Yellow Spice With Medicinal Properties

(2009) Neena E. Thomas-Eapen   Explore-The Journal of Science and Healing

Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases

(2009) Vittorio Calabrese   Frontiers in Bioscience-Landmark

Improving the oral bioavailability of beneficial polyphenols through designed synergies

(2009) Arjan Scheepens et al.   Genes and Nutrition

Six-Month Randomized, Placebo-Controlled, Double-Blind, Pilot Clinical Trial of Curcumin in Patients With Alzheimer Disease

(2009) Larry Baum et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Naturally occurring phytochemicals for the prevention of Alzheimer’s disease

(2009) Jiyoung Kim et al.   JOURNAL OF NEUROCHEMISTRY

Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention

(2009) Malú G. Tansey et al.   NEUROBIOLOGY OF DISEASE

Natural Antioxidants Protect Neurons in Alzheimer’s Disease and Parkinson’s Disease

(2009) Baolu Zhao   NEUROCHEMICAL RESEARCH

Curcumin exposure induces expression of the Parkinson's disease-associated leucine-rich repeat kinase 2 (LRRK2) in rat mesencephalic cells

(2009) Miguel A. Ortiz-Ortiz et al.   NEUROSCIENCE LETTERS

Consumption of Grape Seed Extract Prevents Amyloid-β Deposition and Attenuates Inflammation in Brain of an Alzheimer’s Disease Mouse

(2009) Yan-Jiang Wang et al.   NEUROTOXICITY RESEARCH

Bioavailability of Phenolic Antioxidants Associated with Dietary Fiber: Plasma Antioxidant Capacity After Acute and Long-Term Intake in Humans

(2009) Jara Pérez-Jiménez et al.   PLANT FOODS FOR HUMAN NUTRITION

Curcumin in clinical practice: myth or reality?

(2009) Cesare Mancuso et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Curcumin inhibits aggregation of α-synuclein

(2008) Neeraj Pandey et al.   ACTA NEUROPATHOLOGICA

Antioxidant and radical scavenging properties of curcumin

(2008) Tuba Ak et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Mechanisms of combined action of different chemopreventive dietary compounds

(2008) Theo M. de Kok et al.   EUROPEAN JOURNAL OF NUTRITION

Nuclear Factor-κB Activation: From Bench to Bedside

(2008) Gautam Sethi et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Curcumin protected PC12 cells against beta-amyloid-induced toxicity through the inhibition of oxidative damage and tau hyperphosphorylation

(2008) So-Young Park et al.   FOOD AND CHEMICAL TOXICOLOGY

Current and future therapy in Alzheimer’s disease

(2008) Robert J. van Marum   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases

(2008) Bharat B. Aggarwal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Parkinson's disease: clinical features and diagnosis

(2008) J Jankovic   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease

(2008) A. N. Begum et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Grape seed polyphenols and curcumin reduce genomic instability events in a transgenic mouse model for Alzheimer's disease

(2008) Philip Thomas et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Benefits from Dietary Polyphenols for Brain Aging and Alzheimer’s Disease

(2008) L. Rossi et al.   NEUROCHEMICAL RESEARCH

Botanical Phenolics and Brain Health

(2008) Albert Y. Sun et al.   NEUROMOLECULAR MEDICINE

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

(2008) P. Hemachandra Reddy et al.   TRENDS IN MOLECULAR MEDICINE

Oxidative stress hypothesis in Alzheimer’s disease: a reappraisal

(2008) Domenico Praticò   TRENDS IN PHARMACOLOGICAL SCIENCES

Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets

(2008) Bharat B. Aggarwal et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Inhibition of monoamine oxidase-B by the polyphenolic compound, curcumin and its metabolite tetrahydrocurcumin, in a model of Parkinson’s disease induced by MPTP neurodegeneration in mice

(2008) A. Rajeswari et al.   INFLAMMOPHARMACOLOGY

Curcumin as “Curecumin”: From kitchen to clinic

(2007) Ajay Goel et al.   BIOCHEMICAL PHARMACOLOGY

Protective effect of Curcumin, the active principle of turmeric (Curcuma longa) in haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes in rat brain

(2007) M BISHNOI et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR