The protective role of melatonin in chemotherapy‐induced nephrotoxicity: a systematic review of non-clinical studies

Reduction–oxidation (redox) system in radiation-induced normal tissue injury: molecular mechanisms and implications in radiation therapeutics

(2018) R. Yahyapour et al.   Clinical & Translational Oncology

Naringin protects against cyclophosphamide-induced hepatotoxicity and nephrotoxicity through modulation of oxidative stress, inflammation, apoptosis, autophagy, and DNA damage

(2018) Cuneyt Caglayan et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Acetyl- l -carnitine attenuates arsenic-induced liver injury by abrogation of mitochondrial dysfunction, inflammation, and apoptosis in rats

(2018) Vida Bodaghi-Namileh et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Assessment of accuracy of out-of-field dose calculations by TiGRT treatment planning system in radiotherapy

(2018) Bagher Farhood et al.   Journal of Cancer Research and Therapeutics

Gadolinium nanoparticles as diagnostic and therapeutic agents: Their delivery systems in magnetic resonance imaging and neutron capture therapy

(2018) Asghar Narmani et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Role of melatonin receptor 1A and pituitary homeobox-1 coexpression in protecting tubular epithelial cells in membranous nephropathy

(2018) Yen-Sung Huang et al.   JOURNAL OF PINEAL RESEARCH

A glance at the therapeutic potential of irisin against diseases involving inflammation, oxidative stress, and apoptosis: An introductory review

(2018) Hassan Askari et al.   PHARMACOLOGICAL RESEARCH

Redox Functions of Heme Oxygenase-1 and Biliverdin Reductase in Diabetes

(2018) Luc Rochette et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Diagnostic and Therapeutic Potential of Exosomes in Cancer: The Beginning of a New Tale?

(2017) Hamed Mirzaei et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The role of melatonin on chemotherapy-induced reproductive toxicity

(2017) Hamed Haghi-Aminjan et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Contribution of inducible and neuronal nitric oxide synthases to mitochondrial damage and melatonin rescue in LPS-treated mice

(2017) José Antonio García et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

A systematic review on potential mechanisms of minocycline in kidney diseases

(2017) Hamed Haghi-Aminjan et al.   Pharmacological Reports

Melatonin as an angiogenesis inhibitor to combat cancer: Mechanistic evidence

(2017) Nasser Hashemi Goradel et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress

(2017) Helmut Sies   Redox Biology

Myricitrin Alleviates Oxidative Stress-induced Inflammation and Apoptosis and Protects Mice against Diabetic Cardiomyopathy

(2017) Bin Zhang et al.   Scientific Reports

Normotension, hypertension and body fluid regulation: brain and kidney

(2016) P. Bie et al.   Acta Physiologica

Functional Improvement in Rats’ Pancreatic Islets Using Magnesium Oxide Nanoparticles Through Antiapoptotic and Antioxidant Pathways

(2016) Shermineh Moeini-Nodeh et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Biological Rhythms: Melatonin Shapes the Space–Time Continuum of Social Communication

(2016) Walter Wilczynski et al.   CURRENT BIOLOGY

An Updated Review of Natural Products Intended to Prevent or Treat Oral Mucositis in Patients Undergoing Radio-Chemotherapy

(2016) Yunes Panahi et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Pitfalls in the analysis of the physiological antioxidant glutathione (GSH) and its disulfide (GSSG) in biological samples: An elephant in the room

(2016) Daniela Giustarini et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Melatonin enhances mitochondrial ATP synthesis, reduces reactive oxygen species formation, and mediates translocation of the nuclear erythroid 2-related factor 2 resulting in activation of phase-2 antioxidant enzymes (γ-GCS, HO-1, NQO1) in ultraviolet rad

(2016) Konrad Kleszczyński et al.   JOURNAL OF PINEAL RESEARCH

Expression Profile of BCL-2, BCL-XL, and MCL-1 Predicts Pharmacological Response to the BCL-2 Selective Antagonist Venetoclax in Multiple Myeloma Models

(2016) E. A. Punnoose et al.   MOLECULAR CANCER THERAPEUTICS

Effects of Lycopene Alone or Combined with Melatonin on Methotrexate-Induced Nephrotoxicity in Rats

(2015) Elif Oguz et al.   Asian Pacific Journal of Cancer Prevention

Assessment of benzene induced oxidative impairment in rat isolated pancreatic islets and effect on insulin secretion

(2015) Haji Bahadar et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Effects of pentoxifylline and alpha lipoic acid on methotrexate-induced damage in liver and kidney of rats

(2015) Ilkay Armagan et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Cisplatin-induced renal toxicity via tumor necrosis factor-α, interleukin 6, tumor suppressor P53, DNA damage, xanthine oxidase, histological changes, oxidative stress and nitric oxide in rats: Protective effect of ginseng

(2015) Mokhtar I. Yousef et al.   FOOD AND CHEMICAL TOXICOLOGY

Gallic Acid-g-Chitosan Modulates Inflammatory Responses in LPS-Stimulated RAW264.7 Cells Via NF-κB, AP-1, and MAPK Pathways

(2015) Chang-Bum Ahn et al.   INFLAMMATION

The neuroprotective and anti-apoptotic effects of melatonin on hemolytic hyperbilirubinemia-induced oxidative brain damage

(2015) Asilay Pazar et al.   JOURNAL OF PINEAL RESEARCH

PET-adapted sequential salvage therapy with brentuximab vedotin followed by augmented ifosamide, carboplatin, and etoposide for patients with relapsed and refractory Hodgkin's lymphoma: a non-randomised, open-label, single-centre, phase 2 study

(2015) Alison J Moskowitz et al.   LANCET ONCOLOGY

The Keap1-Nrf2-antioxidant response element pathway: A review of its regulation by melatonin and the proteasome

(2015) Jerry Vriend et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Oxidative stress and cancer; the role of hesperidin, a citrus natural bioflavonoid, as a cancer chemoprotective agent

(2015) Amirhossein Ahmadi et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

An integrated view of cisplatin-induced nephrotoxicity and ototoxicity

(2015) Takatoshi Karasawa et al.   TOXICOLOGY LETTERS

Melatonin increased vitamin C and antioxidant enzyme values in the plasma,heart, liver, and kidney of Adriamycin-treated rats

(2015) Ali Ziya KARAKILÇIK et al.   TURKISH JOURNAL OF BIOLOGY

Melatonin inhibits AP-2β/hTERT, NF-κB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells

(2015) Jian-Jun Lu et al.   Oncotarget

NF-kappaB Signaling Pathways in Neurological Inflammation: A Mini Review

(2015) Ruey-Horng Shih et al.   Frontiers in Molecular Neuroscience

An overview of doxorubicin formulations in cancer therapy

(2015) Sangeeta Rivankar   Journal of Cancer Research and Therapeutics

Monosodium urate crystals trigger Nrf2- and heme oxygenase-1-dependent inflammation in THP-1 cells

(2014) Jhih-Jia Jhang et al.   Cellular & Molecular Immunology

Melatonin use for neuroprotection in perinatal asphyxia: a randomized controlled pilot study

(2014) H Aly et al.   Journal of Perinatology

Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: a physicochemical analysis

(2014) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Melatonin: a well-documented antioxidant with conditional pro-oxidant actions

(2014) Hong-Mei Zhang et al.   JOURNAL OF PINEAL RESEARCH

6-Thioguanine: A Drug With Unrealized Potential for Cancer Therapy

(2014) Pashna N. Munshi et al.   ONCOLOGIST

An ethanol extract ofOriganum vulgareattenuates cyclophosphamide-induced pulmonary injury and oxidative lung damage in mice

(2014) Mohammad Shokrzadeh et al.   PHARMACEUTICAL BIOLOGY

Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases

(2014) Asima Bhattacharyya et al.   PHYSIOLOGICAL REVIEWS

Protective effects of thymol against nephrotoxicity induced by cisplatin with using99mTc-DMSA in mice

(2014) Seyed Jalal Hosseinimehr et al.   RENAL FAILURE

Melatonin modulates microsomal PGE synthase 1 and NF-E2-related factor-2-regulated antioxidant enzyme expression in LPS-induced murine peritoneal macrophages

(2013) M Aparicio-Soto et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Highly Specific Fluorescent Probe for Hypochlorous Acid and Its Application in Imaging Microbe-Induced HOCl Production

(2013) Qingling Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Melatonin and its atheroprotective effects: A review

(2013) Gaia Favero et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Renoprotective effects of montelukast, a cysteinyl leukotriene receptor antagonist, against methotrexate-induced kidney damage in rats

(2013) Ihab T. Abdel-Raheem et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway

(2013) Ulkan Kilic et al.   Nutrition & Metabolism

Toxicological and pharmacological concerns on oxidative stress and related diseases

(2013) Soodabeh Saeidnia et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Antioxidants: Friends or foe in prevention or treatment of cancer: The debate of the century

(2013) Soodabeh Saeidnia et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The ameliorative effect of various antioxidants on Adriamycin-induced fetal renal abnormalities

(2013) Abdol-Mohammad Kajbafzadeh et al.   Journal of Pediatric Urology

Melatonin, a Promising Supplement in Inflammatory Bowel Disease: A Comprehensive Review of Evidences

(2012) Shilan Mozaffari et al.   CURRENT PHARMACEUTICAL DESIGN

Melatonin inhibits IL1β-induced MMP9 expression and activity in human umbilical vein endothelial cells by suppressing NF-κB activation

(2012) Weiwei Qin et al.   JOURNAL OF ENDOCRINOLOGY

Protection of cisplatin-induced spermatotoxicity, DNA damage and chromatin abnormality by selenium nano-particles

(2012) Mohammad Amin Rezvanfar et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mitochondrial targeting liposomes incorporating daunorubicin and quinacrine for treatment of relapsed breast cancer arising from cancer stem cells

(2011) Liang Zhang et al.   BIOMATERIALS

Rutin attenuates cisplatin induced renal inflammation and apoptosis by reducing NFκB, TNF-α and caspase-3 expression in wistar rats

(2011) Wani Arjumand et al.   FOOD AND CHEMICAL TOXICOLOGY

Melatonin ameliorates bisphenol A-induced biochemical toxicity in testicular mitochondria of mouse

(2011) Sameya Anjum et al.   FOOD AND CHEMICAL TOXICOLOGY

Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide

(2011) C.-C. Wu et al.   SCIENCE

Oxidative stress, inflammation and carcinogenesis are controlled through the pentose phosphate pathway by transaldolase

(2011) Andras Perl et al.   TRENDS IN MOLECULAR MEDICINE

Biochemical Study of Oxidative Stress Markers in the Liver, Kidney and Heart of High Fat Diet Induced Obesity in Rats

(2011) Saad A Noeman et al.   Diabetology & Metabolic Syndrome

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

Global Patterns of Cancer Incidence and Mortality Rates and Trends

(2010) A. Jemal et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Melatonin attenuates methotrexate-induced oxidative stress and renal damage in rats

(2010) Premila Abraham et al.   CELL BIOCHEMISTRY AND FUNCTION

Implications of Melatonin Therapy in Irritable Bowel Syndrome: A Systematic Review

(2010) Shilan Mozaffari et al.   CURRENT PHARMACEUTICAL DESIGN

Protective effect of melatonin on oxaliplatin-induced apoptosis through sustained Mcl-1 expression and anti-oxidant action in renal carcinoma Caki cells

(2010) Hee Jung Um et al.   JOURNAL OF PINEAL RESEARCH

Limitations in doxorubicin production from Streptomyces peucetius

(2010) Sailesh Malla et al.   MICROBIOLOGICAL RESEARCH

Doxorubicin pathways

(2010) Caroline F. Thorn et al.   Pharmacogenetics and Genomics

Treatment of Acute Renal Failure Secondary to Multiple Myeloma with Chemotherapy and Extended High Cut-Off Hemodialysis

(2009) C. A. Hutchison et al.   Clinical Journal of the American Society of Nephrology

Protection of cyclophosphamide-induced toxicity in reproductive tract histology, sperm characteristics, and DNA damage by an herbal source; evidence for role of free-radical toxic stress

(2009) MA Rezvanfar et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Tip-enhanced Raman scattering (TERS) of oxidised glutathione on an ultraflat gold nanoplate

(2009) Tanja Deckert-Gaudig et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis

(2008) Wenge Li et al.   BIOCHEMICAL PHARMACOLOGY

Mcl-1 is a potential therapeutic target in multiple types of cancer

(2008) C. Akgul   CELLULAR AND MOLECULAR LIFE SCIENCES

Synergistic cytotoxic effect of different sized ZnO nanoparticles and daunorubicin against leukemia cancer cells under UV irradiation

(2008) Dadong Guo et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells

(2008) S Gobessi et al.   LEUKEMIA