In vitro cell transformation assays for an integrated, alternative assessment of carcinogenicity: a data-based analysis

Alternatives to the carcinogenicity bioassay for toxicity prediction: are we there yet?

(2012) Romualdo Benigni   Expert Opinion on Drug Metabolism & Toxicology

Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics

(2012) Philippe Vanparys et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The tissue organization field theory of cancer: A testable replacement for the somatic mutation theory

(2011) Ana M. Soto et al.   BIOESSAYS

Mechanisms of Chemical Carcinogenicity and Mutagenicity: A Review with Implications for Predictive Toxicology

(2011) Romualdo Benigni et al.   CHEMICAL REVIEWS

Cell transformation assays for prediction of carcinogenic potential: state of the science and future research needs

(2011) S. Creton et al.   MUTAGENESIS

Alternative strategies for carcinogenicity assessment: an efficient and simplified approach based on in vitro mutagenicity and cell transformation assays

(2011) R. Benigni et al.   MUTAGENESIS

The new ISSMIC database on in vivo micronucleus and its role in assessing genotoxicity testing strategies

(2011) R. Benigni et al.   MUTAGENESIS

OECD Detailed Review Paper (DRP) number 31 on “Cell Transformation Assays for Detection of Chemical Carcinogens”: main results and conclusions

(2011) Paule Vasseur et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

ECVAM prevalidation study on in vitro cell transformation assays: General outline and conclusions of the study

(2011) Raffaella Corvi et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Primary Prevention of Cancer

(2011) J. Huff   SCIENCE

Historical perspective on the development of the genetic toxicity test battery in the United States

(2010) Errol Zeiger   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Alternatives to the carcinogenicity bioassay:in silicomethods, and thein vitroandin vivomutagenicity assays

(2010) Romualdo Benigni et al.   Expert Opinion on Drug Metabolism & Toxicology

Research on Early-Stage Carcinogenesis: Are We Approaching Paradigm Instability?

(2010) Stuart G. Baker et al.   JOURNAL OF CLINICAL ONCOLOGY

Exploring In Vitro/In Vivo Correlation: Lessons Learned from Analyzing Phase I Results of the US EPA's ToxCast Project

(2010) ROMUALDO BENIGNI et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

A Bhas 42 cell transformation assay on 98 chemicals: The characteristics and performance for the prediction of chemical carcinogenicity

(2010) Ayako Sakai et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach

(2009) Lya G. Hernández et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Using chemical categories to fill data gaps in hazard assessment

(2009) K. van Leeuwen et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Current and Future Application of Genetic Toxicity Assays: The Role and Value of In Vitro Mammalian Assays

(2009) Rosalie K. Elespuru et al.   TOXICOLOGICAL SCIENCES

Toxicity Testing in the 21st Century: A View from the Pharmaceutical Industry

(2009) James S. MacDonald et al.   TOXICOLOGICAL SCIENCES

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens

(2008) David Kirkland et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Structure alerts for carcinogenicity, and the Salmonella assay system: A novel insight through the chemical relational databases technology

(2008) R BENIGNI et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment

(2008) Robert J. Kavlock et al.   RISK ANALYSIS

More Toxin Tests Needed

(2008) J. Huff   SCIENCE