Recent advances in characterization of nonviral vectors for delivery of nucleic acids: impact on their biological performance
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Recent advances in characterization of nonviral vectors for delivery of nucleic acids: impact on their biological performance
Authors
Keywords
-
Journal
Expert Opinion on Drug Delivery
Volume 12, Issue 1, Pages 27-39
Publisher
Informa Healthcare
Online
2014-08-21
DOI
10.1517/17425247.2014.945421
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Novel serum-tolerant lipoplexes target the folate receptor efficiently
- (2014) Sridevi Gorle et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Prevention and reversal of severe mitochondrial cardiomyopathy by gene therapy in a mouse model of Friedreich's ataxia
- (2014) Morgane Perdomini et al. NATURE MEDICINE
- RNAi-mediated silencing of hepatic Alas1 effectively prevents and treats the induced acute attacks in acute intermittent porphyria mice
- (2014) M. Yasuda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Conjugation with Betaine: A Facile and Effective Approach to Significant Improvement of Gene Delivery Properties of PEI
- (2013) Jun Sun et al. BIOMACROMOLECULES
- Protein-resistant, reductively dissociable polyplexes for in vivo systemic delivery and tumor-targeting of siRNA
- (2013) Jee Seon Kim et al. BIOMATERIALS
- Effect of binding affinity for siRNA on the in vivo antitumor efficacy of polyplexes
- (2013) Lu Han et al. BIOMATERIALS
- The effect of serum in culture on RNAi efficacy through modulation of polyplexes size
- (2013) Weiqi Zhang et al. BIOMATERIALS
- Intracellular trafficking and cellular uptake mechanism of mPEG-PLGA-PLL and mPEG-PLGA-PLL-Gal nanoparticles for targeted delivery to hepatomas
- (2013) Peifeng Liu et al. BIOMATERIALS
- Shrinkage of pegylated and non-pegylated liposomes in serum
- (2013) Joy Wolfram et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Chemical modifications on siRNAs avoid Toll-like-receptor-mediated activation of the hepatic immune system in vivo and in vitro
- (2013) R. Broering et al. INTERNATIONAL IMMUNOLOGY
- Hematotoxicological analysis of surface-modified and -unmodified chitosan nanoparticles
- (2013) Ragima Nadesh et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Biomimetic mucin modified PLGA nanoparticles for enhanced blood compatibility
- (2013) Y.M. Thasneem et al. JOURNAL OF COLLOID AND INTERFACE SCIENCE
- Understanding the correlation between in vitro and in vivo immunotoxicity tests for nanomedicines
- (2013) Marina A. Dobrovolskaia et al. JOURNAL OF CONTROLLED RELEASE
- Protection Against Lethal Marburg Virus Infection Mediated by Lipid Encapsulated Small Interfering RNA
- (2013) Raul Ursic-Bedoya et al. JOURNAL OF INFECTIOUS DISEASES
- Water-soluble, biocompatible polyphosphazenes with controllable and pH-promoted degradation behavior
- (2013) Sandra Wilfert et al. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
- The Effect and Role of Carbon Atoms in Poly(β-amino ester)s for DNA Binding and Gene Delivery
- (2013) Corey J. Bishop et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Nanoparticle Adhesion to the Cell Membrane and Its Effect on Nanoparticle Uptake Efficiency
- (2013) Anna Lesniak et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial
- (2013) Kevin Fitzgerald et al. LANCET
- Preparation of Water-Soluble Hyperbranched Polyester Nanoparticles with Sulfonic Acid Functional Groups and Their Micelles Behavior, Anticoagulant Effect and Cytotoxicity
- (2013) Qiaorong Han et al. LANGMUIR
- Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics
- (2013) Martin A Maier et al. MOLECULAR THERAPY
- The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the lysosomes
- (2013) Fengjuan Wang et al. Nanomedicine-Nanotechnology Biology and Medicine
- Slight temperature changes affect protein affinity and cellular uptake/toxicity of nanoparticles
- (2013) Morteza Mahmoudi et al. Nanoscale
- Effect of polyethyleneglycol (PEG) chain length on the bio–nano-interactions between PEGylated lipid nanoparticles and biological fluids: from nanostructure to uptake in cancer cells
- (2013) Daniela Pozzi et al. Nanoscale
- Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape
- (2013) Jerome Gilleron et al. NATURE BIOTECHNOLOGY
- Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling
- (2013) Gaurav Sahay et al. NATURE BIOTECHNOLOGY
- Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface
- (2013) Anna Salvati et al. Nature Nanotechnology
- Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology
- (2013) Stefan Tenzer et al. Nature Nanotechnology
- Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis
- (2013) Teresa Coelho et al. NEW ENGLAND JOURNAL OF MEDICINE
- Altered characteristics of silica nanoparticles in bovine and human serum: the importance of nanomaterial characterization prior to its toxicological evaluation
- (2013) Emilia Izak-Nau et al. Particle and Fibre Toxicology
- Insight into Polycation Chain Length Affecting Transfection Efficiency by O-Methyl-Free N,N,N-Trimethyl Chitosans as Gene Carriers
- (2013) Tao Xu et al. PHARMACEUTICAL RESEARCH
- Gene Transfection in High Serum Levels: Case Studies with New Cholesterol Based Cationic Gemini Lipids
- (2013) Santosh K. Misra et al. PLoS One
- Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery
- (2013) C. A. Alabi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- First-in-Humans Trial of an RNA Interference Therapeutic Targeting VEGF and KSP in Cancer Patients with Liver Involvement
- (2013) Josep Tabernero et al. Cancer Discovery
- Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry
- (2013) Ron B. Shmueli et al. Jove-Journal of Visualized Experiments
- Lipid Nanoparticle Delivery of siRNA to Silence Neuronal Gene Expression in the Brain
- (2013) Ravi L Rungta et al. Molecular Therapy-Nucleic Acids
- In Vitro–In Vivo Translation of Lipid Nanoparticles for Hepatocellular siRNA Delivery
- (2012) Kathryn A. Whitehead et al. ACS Nano
- Safety profile of RNAi nanomedicines
- (2012) Scott A. Barros et al. ADVANCED DRUG DELIVERY REVIEWS
- Poly(ethylene oxide) Grafted with Short Polyethylenimine Gives DNA Polyplexes with Superior Colloidal Stability, Low Cytotoxicity, and Potent In Vitro Gene Transfection under Serum Conditions
- (2012) Meng Zheng et al. BIOMACROMOLECULES
- Impact of the nature, size and chain topologies of carbohydrate–phosphorylcholine polymeric gene delivery systems
- (2012) Marya Ahmed et al. BIOMATERIALS
- A mesoporous silica nanoparticle – PEI – Fusogenic peptide system for siRNA delivery in cancer therapy
- (2012) Xu Li et al. BIOMATERIALS
- siRNA Delivery with Lipid-based Systems: Promises and Pitfalls
- (2012) Camilla Foged CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Efficient serum-resistant lipopolyplexes targeted to the folate receptor
- (2012) Koldo Urbiola et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Comparison of four different particle sizing methods for siRNA polyplex characterization
- (2012) Christina Troiber et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Dextran–protamine–solid lipid nanoparticles as a non-viral vector for gene therapy: In vitro characterization and in vivo transfection after intravenous administration to mice
- (2012) Diego Delgado et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Controlled shielding and deshielding of gene delivery polyplexes using hydroxyethyl starch (HES) and alpha-amylase
- (2012) Matthäus Noga et al. JOURNAL OF CONTROLLED RELEASE
- Reduced in vitro and in vivo toxicity of siRNA-lipoplexes with addition of polyglutamate
- (2012) Anne Schlegel et al. JOURNAL OF CONTROLLED RELEASE
- Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA
- (2012) Paulo J.C. Lin et al. Nanomedicine-Nanotechnology Biology and Medicine
- Characterization of Ku702–NLS as Bipartite Nuclear Localization Sequence for Non-Viral Gene Delivery
- (2012) Johannes Matschke et al. PLoS One
- Poly(β-Amino Ester)-Nanoparticle Mediated Transfection of Retinal Pigment Epithelial Cells In Vitro and In Vivo
- (2012) Joel C. Sunshine et al. PLoS One
- Subtle Changes to Polymer Structure and Degradation Mechanism Enable Highly Effective Nanoparticles for siRNA and DNA Delivery to Human Brain Cancer
- (2012) Stephany Y. Tzeng et al. Advanced Healthcare Materials
- In Vivo Delivery of RNAi with Lipid-Based Nanoparticles
- (2011) Leaf Huang et al. Annual Review of Biomedical Engineering
- Systemic delivery of therapeutic small interfering RNA using a pH-triggered amphiphilic poly-l-lysine nanocarrier to suppress prostate cancer growth in mice
- (2011) Jianfeng Guo et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Chitosan-based therapeutic nanoparticles for combination gene therapy and gene silencing of in vitro cell lines relevant to type 2 diabetes
- (2011) Myriam Jean et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Reducible HPMA-co-oligolysine copolymers for nucleic acid delivery
- (2011) Julie Shi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Hyaluronan-coated nanoparticles: The influence of the molecular weight on CD44-hyaluronan interactions and on the immune response
- (2011) Shoshy Mizrahy et al. JOURNAL OF CONTROLLED RELEASE
- Altering the immune response with lipid-based nanoparticles
- (2011) Dalit Landesman-Milo et al. JOURNAL OF CONTROLLED RELEASE
- Physical−Chemical Aspects of Protein Corona: Relevance toin Vitroandin VivoBiological Impacts of Nanoparticles
- (2011) Marco P. Monopoli et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Polycationic amphiphilic cyclodextrin-based nanoparticles for therapeutic gene delivery
- (2011) Alejandro Méndez-Ardoy et al. Nanomedicine
- Dendrimer-induced leukocyte procoagulant activity depends on particle size and surface charge
- (2011) Marina A Dobrovolskaia et al. Nanomedicine
- Time Evolution of the Nanoparticle Protein Corona
- (2010) Eudald Casals et al. ACS Nano
- Gene delivery by lipoplexes and polyplexes
- (2010) Conchita Tros de Ilarduya et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study
- (2010) Thomas W Geisbert et al. LANCET
- Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms
- (2010) Akin Akinc et al. MOLECULAR THERAPY
- Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
- (2010) Mark E. Davis et al. NATURE
- Rational design of cationic lipids for siRNA delivery
- (2010) Sean C Semple et al. NATURE BIOTECHNOLOGY
- A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus
- (2010) J. DeVincenzo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- New Insights into Chitosan−DNA Interactions Using Isothermal Titration Microcalorimetry
- (2009) Pei Lian Ma et al. BIOMACROMOLECULES
- A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
- (2008) Akin Akinc et al. NATURE BIOTECHNOLOGY
- Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts
- (2008) M. Lundqvist et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systemic Leukocyte-Directed siRNA Delivery Revealing Cyclin D1 as an Anti-Inflammatory Target
- (2008) D. Peer et al. SCIENCE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now