Subtle Changes to Polymer Structure and Degradation Mechanism Enable Highly Effective Nanoparticles for siRNA and DNA Delivery to Human Brain Cancer

2011 Rita Schaffer Lecture: Nanoparticles for Intracellular Nucleic Acid Delivery

(2012) Jordan J. Green   ANNALS OF BIOMEDICAL ENGINEERING

Effect of molecular weight of amine end-modified poly(β-amino ester)s on gene delivery efficiency and toxicity

(2012) Ahmed A. Eltoukhy et al.   BIOMATERIALS

Non-viral gene delivery nanoparticles based on Poly(β-amino esters) for treatment of glioblastoma

(2011) Stephany Y. Tzeng et al.   BIOMATERIALS

Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors

(2011) Jiangbing Zhou et al.   BIOMATERIALS

Biophysical properties of chitosan/siRNA polyplexes: Profiling the polymer/siRNA interactions and bioactivity

(2011) Pascale Holzerny et al.   JOURNAL OF CONTROLLED RELEASE

News & Views in ... Nanomedicine

(2011)   Nanomedicine

A Novel Assay for Quantifying the Number of Plasmids Encapsulated by Polymer Nanoparticles

(2011) Nupura S. Bhise et al.   Small

Nanoparticulate Alternatives for Drug Delivery

(2010) James H. Adair et al.   ACS Nano

The relationship between terminal functionalization and molecular weight of a gene delivery polymer and transfection efficacy in mammary epithelial 2-D cultures and 3-D organotypic cultures

(2010) Nupura S. Bhise et al.   BIOMATERIALS

Effect of Nanoparticle Conjugation on Gene Silencing by RNA Interference

(2010) Neetu Singh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gene Regulation with Polyvalent siRNA−Nanoparticle Conjugates

(2009) David A. Giljohann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gold, Poly(β-amino ester) Nanoparticles for Small Interfering RNA Delivery

(2009) Jae-Seung Lee et al.   NANO LETTERS

Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences

(2009) J. Yu et al.   SCIENCE

A Combinatorial Polymer Library Approach Yields Insight into Nonviral Gene Delivery

(2008) Jordan J. Green et al.   ACCOUNTS OF CHEMICAL RESEARCH

Application of an HIV gp41-Derived Peptide for Enhanced Intracellular Trafficking of Synthetic Gene and siRNA Delivery Vehicles

(2008) Ester J. Kwon et al.   BIOCONJUGATE CHEMISTRY

Polymer-Based Gene Delivery: A Current Review on the Uptake and Intracellular Trafficking of Polyplexes

(2008) Patrick Midoux et al.   CURRENT GENE THERAPY