The human microbiome and bile acid metabolism: dysbiosis, dysmetabolism, disease and intervention

Correcting vitamin D insufficiency improves insulin sensitivity in obese adolescents: a randomized controlled trial

(2013) Anthony M Belenchia et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Pleiotropic Roles of Bile Acids in Metabolism

(2013) Thomas Q. de Aguiar Vallim et al.   Cell Metabolism

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Improvement of gastrointestinal health status in subjects consumingLactobacillus reuteriNCIMB 30242 capsules: apost-hocanalysis of a randomized controlled trial

(2013) Mitchell L Jones et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Roux-en-Y gastric bypass normalizes the blunted postprandial bile acid excursion associated with obesity

(2013) N N Ahmad et al.   INTERNATIONAL JOURNAL OF OBESITY

Probiotic use decreases intestinal inflammation and increases bone density in healthy male but not female mice

(2013) Laura R. McCabe et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Oral Supplementation With ProbioticL. reuteriNCIMB 30242 Increases Mean Circulating 25-Hydroxyvitamin D: A Post Hoc Analysis of a Randomized Controlled Trial

(2013) Mitchell L. Jones et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Diet, microbes, and host genetics: the perfect storm in inflammatory bowel diseases

(2013) Vanessa Leone et al.   JOURNAL OF GASTROENTEROLOGY

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Bacterial colonization factors control specificity and stability of the gut microbiota

(2013) S. Melanie Lee et al.   NATURE

Dietary intervention impact on gut microbial gene richness

(2013) Aurélie Cotillard et al.   NATURE

Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

(2013) W.H. Wilson Tang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association between bile acid turnover and osteoporosis in postmenopausal women

(2013) Ruth Hanly et al.   NUCLEAR MEDICINE COMMUNICATIONS

Effect of the mediterranean diet with and without weight loss on markers of inflammation in men with metabolic syndrome

(2013) Caroline Richard et al.   Obesity

Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota

(2013) P. C. Kashyap et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

Host Remodeling of the Gut Microbiome and Metabolic Changes during Pregnancy

(2012) Omry Koren et al.   CELL

The Impact of the Gut Microbiota on Human Health: An Integrative View

(2012) Jose C. Clemente et al.   CELL

Crosstalk between the gut microbiota and the endocannabinoid system: impact on the gut barrier function and the adipose tissue

(2012) P.D. Cani   CLINICAL MICROBIOLOGY AND INFECTION

Bacteria as vitamin suppliers to their host: a gut microbiota perspective

(2012) Jean Guy LeBlanc et al.   CURRENT OPINION IN BIOTECHNOLOGY

Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trial

(2012) M L Jones et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Enterobacteria-mediated deconjugation of taurocholic acid enhances ileal farnesoid X receptor signaling

(2012) Hideaki Kuribayashi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome

(2012) Anne Vrieze et al.   GASTROENTEROLOGY

Letter to the editor regarding the report of Dubocet al: connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel disease

(2012) Mitchell L Jones et al.   GUT

Dysbiosis modulates capacity for bile acid modification in the gut microbiomes of patients with inflammatory bowel disease: a mechanism and marker of disease?: Figure 1

(2012) Lesley A Ogilvie et al.   GUT

Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases

(2012) Henri Duboc et al.   GUT

Gut microbiota disturbance during antibiotic therapy: a multi-omic approach

(2012) Ana Elena Pérez-Cobas et al.   GUT

Lactobacillus reuteri CRL1098 soluble factors modulate tumor necrosis factor alpha production in peripheral blood mononuclear cells: Involvement of lipid rafts

(2012) Mónica A. Mechoud et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Increase in fecal primary bile acids and dysbiosis in patients with diarrhea-predominant irritable bowel syndrome

(2012) H. Duboc et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: correlation with inflammatory and metabolic parameters

(2012) J Graessler et al.   PHARMACOGENOMICS JOURNAL

Host–microbe interactions that facilitate gut colonization by commensal bifidobacteria

(2012) Marco Ventura et al.   TRENDS IN MICROBIOLOGY

Symptomatic atherosclerosis is associated with an altered gut metagenome

(2012) Fredrik H. Karlsson et al.   Nature Communications

Diet-Induced Dysbiosis of the Intestinal Microbiota and the Effects on Immunity and Disease

(2012) Kirsty Brown et al.   Nutrients

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Cholesterol-lowering efficacy of a microencapsulated bile salt hydrolase-active Lactobacillus reuteri NCIMB 30242 yoghurt formulation in hypercholesterolaemic adults

(2011) Mitchell L. Jones et al.   BRITISH JOURNAL OF NUTRITION

Role of the Commensal Microbiota in Normal and Pathogenic Host Immune Responses

(2011) Dan R. Littman et al.   Cell Host & Microbe

Bile Acids Regulate Cardiovascular Function

(2011) Sandeep Khurana et al.   CTS-Clinical and Translational Science

Bile Acid Metabolism and the Pathogenesis of Type 2 Diabetes

(2011) Janne Prawitt et al.   Current Diabetes Reports

Effect of bile acid sequestrants on glucose metabolism, hepatic de novo lipogenesis, and cholesterol and bile acid kinetics in type 2 diabetes: a randomised controlled study

(2011) C. Beysen et al.   DIABETOLOGIA

Twin Study Indicates Loss of Interaction Between Microbiota and Mucosa of Patients With Ulcerative Colitis

(2011) Patricia Lepage et al.   GASTROENTEROLOGY

Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

(2011) R. M. Gadaleta et al.   GUT

Gut microbiota, probiotics, and vitamin D: Interrelated exposures influencing allergy, asthma, and obesity?

(2011) Ngoc P. Ly et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Association of bile acid receptor TGR5 variation and transit in health and lower functional gastrointestinal disorders

(2011) M. Camilleri et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Enteric Microbiome Metabolites Correlate with Response to Simvastatin Treatment

(2011) Rima Kaddurah-Daouk et al.   PLoS One

Bile Acid Metabolites in Serum: Intraindividual Variation and Associations with Coronary Heart Disease, Metabolic Syndrome and Diabetes Mellitus

(2011) Carine Steiner et al.   PLoS One

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Probiotics, Nuclear Receptor Signaling, and Anti-Inflammatory Pathways

(2011) Sonia S. Yoon et al.   Gastroenterology Research and Practice

The relationship between postprandial bile acid concentration, GLP-1, PYY and ghrelin

(2010) R. E. Roberts et al.   CLINICAL ENDOCRINOLOGY

Differential Adaptation of Human Gut Microbiota to Bariatric Surgery-Induced Weight Loss: Links With Metabolic and Low-Grade Inflammation Markers

(2010) J.-P. Furet et al.   DIABETES

Functional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 Agonist

(2010) G. Rizzo et al.   MOLECULAR PHARMACOLOGY

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults

(2010) Nadja Larsen et al.   PLoS One

Composition, variability, and temporal stability of the intestinal microbiota of the elderly

(2010) M. J. Claesson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organismal, genetic, and transcriptional variation in the deeply sequenced gut microbiomes of identical twins

(2010) P. J. Turnbaugh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human oral, gut, and plaque microbiota in patients with atherosclerosis

(2010) O. Koren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Succession of microbial consortia in the developing infant gut microbiome

(2010) J. E. Koenig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

(2010) M. Vijay-Kumar et al.   SCIENCE

The association of bile acid excretion and atherosclerotic coronary artery disease

(2010) Gideon Charach et al.   Therapeutic Advances in Gastroenterology

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

The Role of the Gut Microbiota in Energy Metabolism and Metabolic Disease

(2009) Patrice Cani et al.   CURRENT PHARMACEUTICAL DESIGN

Increased Short- and Long-Term Risk of Inflammatory Bowel Disease After Salmonella or Campylobacter Gastroenteritis

(2009) Kim O. Gradel et al.   GASTROENTEROLOGY

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

The Bile Acid Receptor FXR Is a Modulator of Intestinal Innate Immunity

(2009) P. Vavassori et al.   JOURNAL OF IMMUNOLOGY

Administration of Ampicillin Elevates Hepatic Primary Bile Acid Synthesis through Suppression of Ileal Fibroblast Growth Factor 15 Expression

(2009) M. Miyata et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Effects of probiotics and commensals on intestinal epithelial physiology: implications for nutrient handling

(2009) Silvia C. Resta   JOURNAL OF PHYSIOLOGY-LONDON

Serum Bile Acids Are Higher in Humans With Prior Gastric Bypass: Potential Contribution to Improved Glucose and Lipid Metabolism

(2009) Mary-Elizabeth Patti et al.   Obesity

Short-term effect of chewing gums containing probioticLactobacillus reuterion the levels of inflammatory mediators in gingival crevicular fluid

(2008) Svante Twetman et al.   ACTA ODONTOLOGICA SCANDINAVICA

Novel Potent and Selective Bile Acid Derivatives as TGR5 Agonists: Biological Screening, Structure−Activity Relationships, and Molecular Modeling Studies

(2008) Hiroyuki Sato et al.   JOURNAL OF MEDICINAL CHEMISTRY

Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity

(2008) Oded Shaham et al.   Molecular Systems Biology

Targeting bile-acid signalling for metabolic diseases

(2008) Charles Thomas et al.   NATURE REVIEWS DRUG DISCOVERY

Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis

(2008) Harry J. Flint et al.   NATURE REVIEWS MICROBIOLOGY

Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome

(2008) B. V. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pervasive Effects of an Antibiotic on the Human Gut Microbiota, as Revealed by Deep 16S rRNA Sequencing

(2008) Les Dethlefsen et al.   PLOS BIOLOGY