Tumor aerobic glycolysis: new insights into therapeutic strategies with targeted delivery
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Tumor aerobic glycolysis: new insights into therapeutic strategies with targeted delivery
Authors
Keywords
-
Journal
EXPERT OPINION ON BIOLOGICAL THERAPY
Volume 14, Issue 8, Pages 1145-1159
Publisher
Informa Healthcare
Online
2014-04-25
DOI
10.1517/14712598.2014.912270
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Nanoparticles of 2-deoxy-d-glucose functionalized poly(ethylene glycol)-co-poly(trimethylene carbonate) for dual-targeted drug delivery in glioma treatment
- (2013) Xinyi Jiang et al. BIOMATERIALS
- Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors
- (2013) Woondong Jeong et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Ascorbic Acid and a Cytostatic Inhibitor of Glycolysis Synergistically Induce Apoptosis in Non-Small Cell Lung Cancer Cells
- (2013) Saleha B. Vuyyuri et al. PLoS One
- Combination of siRNA-directed Gene Silencing With Cisplatin Reverses Drug Resistance in Human Non-small Cell Lung Cancer
- (2013) Shanthi Ganesh et al. Molecular Therapy-Nucleic Acids
- Small Molecule Activation of PKM2 in Cancer Cells Induces Serine Auxotrophy
- (2012) Charles Kung et al. CHEMISTRY & BIOLOGY
- The updated biology of hypoxia-inducible factor
- (2012) Samantha N Greer et al. EMBO JOURNAL
- Serum lactic dehydrogenase strongly predicts survival in metastatic nasopharyngeal carcinoma treated with palliative chemotherapy
- (2012) Y. Jin et al. EUROPEAN JOURNAL OF CANCER
- Serum Lactate Dehydrogenase Predicts for Overall Survival Benefit in Patients With Metastatic Renal Cell Carcinoma Treated With Inhibition of Mammalian Target of Rapamycin
- (2012) Andrew J. Armstrong et al. JOURNAL OF CLINICAL ONCOLOGY
- Pyruvate kinase M2-specific siRNA induces apoptosis and tumor regression
- (2012) Michael S. Goldberg et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Therapeutic Delivery of siRNA Silencing HIF-1 Alpha with Micellar Nanoparticles Inhibits Hypoxic Tumor Growth
- (2012) Xi-Qiu Liu et al. MOLECULAR PHARMACEUTICS
- Expression of GLUT1 and GLUT3 Glucose Transporters in Endometrial and Breast Cancers
- (2012) Anna Krzeslak et al. PATHOLOGY & ONCOLOGY RESEARCH
- M2 isoform of pyruvate kinase is dispensable for tumor maintenance and growth
- (2012) M. Cortes-Cros et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
- (2011) Sophia Y. Lunt et al. Annual Review of Cell and Developmental Biology
- Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
- (2011) Weibo Luo et al. CELL
- Evidence for a stromal-epithelial “lactate shuttle” in human tumors
- (2011) Diana Whitaker-Menezes et al. CELL CYCLE
- Lactate shuttles at a glance: from physiological paradigms to anti-cancer treatments
- (2011) N. Draoui et al. Disease Models & Mechanisms
- Discovery ofN-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells
- (2011) Carlotta Granchi et al. JOURNAL OF MEDICINAL CHEMISTRY
- Therapeutic Efficacy and Safety of Paclitaxel/Lonidamine Loaded EGFR-Targeted Nanoparticles for the Treatment of Multi-Drug Resistant Cancer
- (2011) Lara Milane et al. PLoS One
- Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth
- (2011) Q. Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anticancer Targets in the Glycolytic Metabolism of Tumors: A Comprehensive Review
- (2011) Paolo E. Porporato et al. Frontiers in Pharmacology
- Hypoxia inducible factors in cancer stem cells
- (2010) J M Heddleston et al. BRITISH JOURNAL OF CANCER
- MiR-199a-3p Regulates mTOR and c-Met to Influence the Doxorubicin Sensitivity of Human Hepatocarcinoma Cells
- (2010) Francesca Fornari et al. CANCER RESEARCH
- The Promise of MicroRNA Replacement Therapy
- (2010) A. G. Bader et al. CANCER RESEARCH
- Silencing of pkm2 increases the efficacy of docetaxel in human lung cancer xenografts in mice
- (2010) Hua-shan Shi et al. CANCER SCIENCE
- MicroRNA-223 regulates Glut4 expression and cardiomyocyte glucose metabolism
- (2010) Han Lu et al. CARDIOVASCULAR RESEARCH
- Pyruvate kinase type M2: A key regulator of the metabolic budget system in tumor cells
- (2010) Sybille Mazurek INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Efficacy of RNAi targeting of pyruvate kinase M2 combined with cisplatin in a lung cancer model
- (2010) Wenhao Guo et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- A Link between mir-100 and FRAP1/mTOR in Clear Cell Ovarian Cancer
- (2010) Ankur K. Nagaraja et al. MOLECULAR ENDOCRINOLOGY
- Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
- (2010) A. Le et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells
- (2010) M. G. Vander Heiden et al. SCIENCE
- Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism☆
- (2009) Divya Pathania et al. ADVANCED DRUG DELIVERY REVIEWS
- Identification of small molecule inhibitors of pyruvate kinase M2
- (2009) Matthew G. Vander Heiden et al. BIOCHEMICAL PHARMACOLOGY
- Tissue-Penetrating Delivery of Compounds and Nanoparticles into Tumors
- (2009) Kazuki N. Sugahara et al. CANCER CELL
- Differential expression profiling of microRNAs and their potential involvement in renal cell carcinoma pathogenesis
- (2009) Tsz-fung F. Chow et al. CLINICAL BIOCHEMISTRY
- Cancer’s craving for sugar: an opportunity for clinical exploitation
- (2009) S. Yeluri et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Development of HIF-1 inhibitors for cancer therapy
- (2009) Barbara Onnis et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Analyses of Resected Human Brain Metastases of Breast Cancer Reveal the Association between Up-Regulation of Hexokinase 2 and Poor Prognosis
- (2009) D. Palmieri et al. MOLECULAR CANCER RESEARCH
- PDK-1 regulates lactate production in hypoxia and is associated with poor prognosis in head and neck squamous cancer
- (2008) S M Wigfield et al. BRITISH JOURNAL OF CANCER
- Tumor Cell Metabolism: Cancer's Achilles' Heel
- (2008) Guido Kroemer et al. CANCER CELL
- The role of hypoxia-inducible factors in tumorigenesis
- (2008) E B Rankin et al. CELL DEATH AND DIFFERENTIATION
- Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer
- (2008) M. Ryder et al. ENDOCRINE-RELATED CANCER
- Tirapazamine: a novel agent targeting hypoxic tumor cells
- (2008) Srini B Reddy et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth
- (2008) B. Clem et al. MOLECULAR CANCER THERAPEUTICS
- The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
- (2008) Heather R. Christofk et al. NATURE
- 2,4-Dinitrophenol induces G1 phase arrest and apoptosis in human pulmonary adenocarcinoma Calu-6 cells
- (2007) Yong Hwan Han et al. TOXICOLOGY IN VITRO
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started