Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors

Title
Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors
Authors
Keywords
Synthetic locked nucleic acid (LNA) oligodeoxynucleotide, Pharmacodynamics-driven trials, Antiangiogenesis, HIF mRNA
Journal
CANCER CHEMOTHERAPY AND PHARMACOLOGY
Volume 73, Issue 2, Pages 343-348
Publisher
Springer Nature
Online
2013-11-29
DOI
10.1007/s00280-013-2362-z

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