Blocking of plasma kallikrein ameliorates stroke by reducing thromboinflammation

Sex differences in stroke: The contribution of coagulation

(2014) Meaghan Roy-O'Reilly et al.   EXPERIMENTAL NEUROLOGY

CD28 Superagonist-Mediated Boost of Regulatory T Cells Increases Thrombo-Inflammation and Ischemic Neurodegeneration during the Acute Phase of Experimental Stroke

(2014) Michael K Schuhmann et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A Factor XIIa Inhibitory Antibody Provides Thromboprotection in Extracorporeal Circulation Without Increasing Bleeding Risk

(2014) M. Larsson et al.   Science Translational Medicine

Physiologic activities of the Contact Activation System

(2014) Alvin H. Schmaier   THROMBOSIS RESEARCH

17β-Estradiol administration promotes delayed cutaneous wound healing in 40-week ovariectomised female mice

(2014) Kanae Mukai et al.   International Wound Journal

Pharmacological Inhibition of Phospholipase D Protects Mice From Occlusive Thrombus Formation and Ischemic Stroke—Brief Report

(2013) David Stegner et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels

(2013) Michael A. Portelli et al.   FASEB JOURNAL

Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010

(2013) Valery L Feigin et al.   LANCET

Factors influencing haemorrhagic transformation in ischaemic stroke

(2013) José Álvarez-Sabín et al.   LANCET NEUROLOGY

FTY720 Ameliorates Acute Ischemic Stroke in Mice by Reducing Thrombo-Inflammation but Not by Direct Neuroprotection

(2013) Peter Kraft et al.   STROKE

Effects of plasma kallikrein deficiency on haemostasis and thrombosis in mice: Murine Ortholog of the Fletcher Trait

(2013) Patricia Smith et al.   THROMBOSIS AND HAEMOSTASIS

Plasma kallikrein: the bradykinin-producing enzyme

(2013) Jenny Björkqvist et al.   THROMBOSIS AND HAEMOSTASIS

Kininogen deficiency protects from ischemic neurodegeneration in mice by reducing thrombosis, blood-brain barrier damage, and inflammation

(2012) F. Langhauser et al.   BLOOD

Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

(2012) C. Kleinschnitz et al.   BLOOD

Immune mechanisms of stroke

(2012) Tim Magnus et al.   CURRENT OPINION IN NEUROLOGY

International, Multicenter Randomized Preclinical Trials in Translational Stroke Research: It's Time to Act

(2012) Ulrich Dirnagl et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Next-Generation Antithrombotics in Ischemic Stroke: Preclinical Perspective on ‘Bleeding-Free Antithrombosis’

(2012) Peter Kraft et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Ischemic stroke and traumatic brain injury: The role of the kallikrein–kinin system

(2012) Christiane Albert-Weißenberger et al.   PROGRESS IN NEUROBIOLOGY

C1-Inhibitor Protects From Brain Ischemia-Reperfusion Injury by Combined Antiinflammatory and Antithrombotic Mechanisms

(2012) Nadine Heydenreich et al.   STROKE

Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding

(2011) A. S. Revenko et al.   BLOOD

Estimation of Estradiol in Mouse Serum Samples: Evaluation of Commercial Estradiol Immunoassays

(2011) Daniel J. Haisenleder et al.   ENDOCRINOLOGY

α2-Adrenoceptors do not Mediate Neuroprotection in Acute Ischemic Stroke in Mice

(2011) Marc Brede et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Blood coagulation factor XII—a neglected player in stroke pathophysiology

(2011) Mirko Pham et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Ischaemic stroke: a thrombo-inflammatory disease?

(2011) Bernhard Nieswandt et al.   JOURNAL OF PHYSIOLOGY-LONDON

Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein

(2011) Jia Liu et al.   NATURE MEDICINE

Diabetes and Poor Outcomes Within 6 Months After Acute Ischemic Stroke

(2011) Qian Jia et al.   STROKE

Increased Risk of Hemorrhagic Transformation in Ischemic Stroke Occurring During Warfarin Anticoagulation

(2011) Waltraud Pfeilschifter et al.   STROKE

Factor XIIa Inhibitor Recombinant Human Albumin Infestin-4 Abolishes Occlusive Arterial Thrombus Formation Without Affecting Bleeding

(2010) Ina Hagedorn et al.   CIRCULATION

Intrinsic Coagulation Activation and the Risk of Arterial Thrombosis in Young Women

(2010) B. Siegerink et al.   CIRCULATION

Plasma Kallikrein Promotes Epidermal Growth Factor Receptor Transactivation and Signaling in Vascular Smooth Muscle through Direct Activation of Protease-activated Receptors

(2010) Rany T. Abdallah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complement Component C1q Mediates Mitochondria-Driven Oxidative Stress in Neonatal Hypoxic-Ischemic Brain Injury

(2010) V. S. Ten et al.   JOURNAL OF NEUROSCIENCE

Post-Stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration

(2010) Christoph Kleinschnitz et al.   PLOS BIOLOGY

Ecallantide: its pharmacology, pharmacokinetics, clinical efficacy and tolerability

(2009) Jonathan A Bernstein et al.   Expert Review of Clinical Immunology

Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system

(2009) Ulf Schulze-Topphoff et al.   NATURE MEDICINE

Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment

(2008) G. Stoll et al.   BLOOD