Kininogen deficiency protects from ischemic neurodegeneration in mice by reducing thrombosis, blood-brain barrier damage, and inflammation

Immune mechanisms of stroke

(2012) Tim Magnus et al.   CURRENT OPINION IN NEUROLOGY

Blockade of the kinin receptor B1 protects from autoimmune CNS disease by reducing leukocyte trafficking

(2011) Kerstin Göbel et al.   JOURNAL OF AUTOIMMUNITY

Blood coagulation factor XII—a neglected player in stroke pathophysiology

(2011) Mirko Pham et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Ischaemic stroke: a thrombo-inflammatory disease?

(2011) Bernhard Nieswandt et al.   JOURNAL OF PHYSIOLOGY-LONDON

Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein

(2011) Jia Liu et al.   NATURE MEDICINE

The Plasma Contact System 2.0

(2011) Coen Maas et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Increased Risk of Hemorrhagic Transformation in Ischemic Stroke Occurring During Warfarin Anticoagulation

(2011) Waltraud Pfeilschifter et al.   STROKE

Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation

(2010) C. Kleinschnitz et al.   BLOOD

Factor XIIa Inhibitor Recombinant Human Albumin Infestin-4 Abolishes Occlusive Arterial Thrombus Formation Without Affecting Bleeding

(2010) Ina Hagedorn et al.   CIRCULATION

Inhibition of Bradykinin Receptor B1 Protects Mice from Focal Brain Injury by Reducing Blood–Brain Barrier Leakage and Inflammation

(2010) Furat Raslan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Far from the Heart: Counteracting coagulation

(2010) Charles T Esmon   NATURE MEDICINE

Post-Stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration

(2010) Christoph Kleinschnitz et al.   PLOS BIOLOGY

Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo

(2009) Felicitas Müller et al.   CELL

Factor XI deficiency in animal models

(2009) T. RENNÉ et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Enhanced cortical reperfusion protects coagulation factor XII-deficient mice from ischemic stroke as revealed by high-field MRI

(2009) M. Pham et al.   NEUROIMAGE

When Recanalization Does Not Improve Clinical Outcomes

(2009) Shelagh B. Coutts et al.   STROKE

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

(2009) Marc Fisher et al.   STROKE

The blood-brain barrier in brain homeostasis and neurological diseases

(2008) Nicolas Weiss et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment

(2008) G. Stoll et al.   BLOOD

Bradykinin increases blood–tumor barrier permeability by down-regulating the expression levels of ZO-1, occludin, and claudin-5 and rearranging actin cytoskeleton

(2008) Li-bo Liu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Effect of a metabotropic glutamate receptor 5 antagonist, MPEP, on the nociceptive response induced by intrathecal injection of excitatory aminoacids, substance P, bradykinin or cytokines in mice

(2008) C JESSE et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

High Serum Levels of Endothelin-1 Predict Severe Cerebral Edema in Patients With Acute Ischemic Stroke Treated With t-PA

(2008) Octavio Moldes et al.   STROKE

Blockade of Bradykinin Receptor B1 but Not Bradykinin Receptor B2 Provides Protection From Cerebral Infarction and Brain Edema

(2008) Madeleine Austinat et al.   STROKE

The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak house?

(2007) N S Kirkby et al.   BRITISH JOURNAL OF PHARMACOLOGY