Recent Advances in Asymmetric Isocyanide-Based Multicomponent Reactions

A Bioinspired Ugi/Michael/Aza-Michael Cascade Reaction in Aqueous Media: Natural-Product-like Molecular Diversity

(2011) Soumava Santra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multicomponent Reaction Design in the Quest for Molecular Complexity and Diversity

(2011) Eelco Ruijter et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Strecker Reactions

(2011) Jun Wang et al.   CHEMICAL REVIEWS

A Microwave-Assisted Diastereoselective Multicomponent Reaction To Access Dibenzo[c,e]azepinones: Synthesis and Biological Evaluation

(2011) Vaibhav P. Mehta et al.   JOURNAL OF ORGANIC CHEMISTRY

The Multiple Multicomponent Approach to Natural Product Mimics: Tubugis, N-Substituted Anticancer Peptides with Picomolar Activity

(2011) Orlando Pando et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Introducing Multicomponent Reactions to Polymer Science: Passerini Reactions of Renewable Monomers

(2011) Oliver Kreye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploring isonitrile-based click chemistry for ligation with biomolecules

(2011) Henning Stöckmann et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Fast and efficient MCR-based synthesis of clickable rhodamine tags for protein profiling

(2011) Sebastian Brauch et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Diversity oriented and chemoenzymatic synthesis of densely functionalized pyrrolidines through a highly diastereoselective Ugi multicomponent reaction

(2011) Valentina Cerulli et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Recent application of isocyanides in synthesis of heterocycles

(2011) Samahe Sadjadi et al.   TETRAHEDRON

Synthesis of β-lactam peptidomimetics through Ugi MCR: first application of chiral Nβ-Fmoc amino alkyl isonitriles in MCRs

(2011) T.M. Vishwanatha et al.   TETRAHEDRON LETTERS

Seven-component reactions by sequential chemoselective Ugi–Mumm/Ugi–Smiles reactions

(2010) Sebastian Brauch et al.   CHEMICAL COMMUNICATIONS

A highly efficient synthesis of telaprevir by strategic use of biocatalysis and multicomponent reactions

(2010) Anass Znabet et al.   CHEMICAL COMMUNICATIONS

Asymmetric synthesis of synthetic alkaloids by a tandem biocatalysis/Ugi/Pictet–Spengler-type cyclization sequence

(2010) Anass Znabet et al.   CHEMICAL COMMUNICATIONS

Isocyanoacetate Derivatives: Synthesis, Reactivity, and Application

(2010) Anton V. Gulevich et al.   CHEMICAL REVIEWS

Recent advances in multicomponent reactions for diversity-oriented synthesis

(2010) James E. Biggs-Houck et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Chiral Isocyanoazides: Efficient Bifunctional Reagents for Bioconjugation

(2010) Valentine G. Nenajdenko et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A Marriage of Convenience: Combining the Power of Isocyanide-Based Multicomponent Reactions with the Versatility of (Hetero)norbornene Chemistry

(2010) Andrea Basso et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A Highly Convergent Synthesis of Tricyclic N-Heterocycles Coupling an Ugi Reaction with a Tandem SN2′-Heck Double Cyclization

(2010) Renata Riva et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Syntheses of (−)-Fructigenine A and (−)-5-N-Acetylardeemin

(2010) Satoshi Takiguchi et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Proteasome Inhibitor Omuralide Featuring Stereocontrolled Ugi Reaction and Novel Convertible Isocyanide

(2010) Cynthia B. Gilley et al.   JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN

Towards molecular diversity: dealkylation of tert-butyl amine in Ugi-type multicomponent reaction product establishes tert-butyl isocyanide as a useful convertible isonitrile

(2010) Sankar K. Guchhait et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Multicomponent reactions of isocyanides in the synthesis of heterocycles

(2010) Aleksandr V Ivachtchenko et al.   RUSSIAN CHEMICAL REVIEWS

Straightforward stereoselective synthesis of polyfunctionalised cyclohexenols using a multicomponent approach

(2010) Andrea Basso et al.   TETRAHEDRON

A practical and inexpensive ‘convertible’ isonitrile for use in multicomponent reactions

(2010) Hoang V. Le et al.   TETRAHEDRON LETTERS

Polycyclic indole alkaloid-type compounds by MCR

(2009) Wei Wang et al.   CHEMICAL COMMUNICATIONS

Natural Product Synthesis Using Multicomponent Reaction Strategies

(2009) Barry B. Touré et al.   CHEMICAL REVIEWS

Catalytic asymmetric direct Mannich reaction: a powerful tool for the synthesis of α,β-diamino acids

(2009) Ramón Gómez Arrayás et al.   CHEMICAL SOCIETY REVIEWS

Rapid Access to N-Substituted Diketopiperazines by One-Pot Ugi-4CR/Deprotection+Activation/Cyclization (UDAC)

(2009) Cristiano R. B. Rhoden et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Multicomponent Reactions of Convertible Isonitriles

(2009) Michael C. Pirrung et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Asymmetric Passerini-Type Reaction: Chiral Aluminum−Organophosphate-Catalyzed Enantioselective α-Addition of Isocyanides to Aldehydes

(2009) Tao Yue et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Organocatalytic Hantzsch Synthesis of Polyhydroquinolines

(2009) Christopher G. Evans et al.   ORGANIC LETTERS

New potential of the classical Biginelli reaction

(2009) S V Vdovina et al.   RUSSIAN CHEMICAL REVIEWS

Coupling Isocyanide-Based Multicomponent Reactions with Aliphatic or Acyl Nucleophilic Substitution Processes

(2009) Luca Banfi et al.   SYNLETT

Three-component Ugi–Smiles couplings of cyclic imines

(2009) Laurent El Kaïm et al.   TETRAHEDRON LETTERS

Isocyanide-based multicomponent reactions in drug discovery

(2008) Irini Akritopoulou-Zanze   CURRENT OPINION IN CHEMICAL BIOLOGY

Chemistry strategies in early drug discovery: an overview of recent trends

(2008) Matteo Colombo et al.   DRUG DISCOVERY TODAY

The Effect of Lewis Acids on the Stereochemistry in the Ugi Three-Component Reaction withD-lyxo-Pyrroline

(2008) Kimberly M. Bonger et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

2-Nitrophenyl Isocyanide as a Versatile Convertible Isocyanide: Rapid Access to a Fused γ-Lactam β-Lactone Bicycle

(2008) Cynthia B. Gilley et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Synthesis of SNAP-7941: Chiral Dihydropyrimidone Inhibitor of MCH1-R

(2008) Jennifer M. Goss et al.   JOURNAL OF ORGANIC CHEMISTRY

Nonracemizable Isocyanoacetates for Multicomponent Reactions

(2008) Alexander G. Zhdanko et al.   JOURNAL OF ORGANIC CHEMISTRY

ChiralN-Fmoc-β-Amino Alkyl Isonitriles Derived from Amino Acids: First Synthesis and Application in 1-Substituted Tetrazole Synthesis

(2008) Vommina V. Sureshbabu et al.   JOURNAL OF ORGANIC CHEMISTRY

Rapid generation of macrocycles with natural-product-like side chains by multiple multicomponent macrocyclizations (MiBs)

(2008) Daniel G. Rivera et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Total Synthesis of (±)-Dysibetaine

(2008) Jerry Isaacson et al.   ORGANIC LETTERS

α-Amino acids as acid components in the Passerini reaction: influence of N-protection on the yield and stereoselectivity

(2008) Stanisław Berłożecki et al.   TETRAHEDRON

Applications of the Ugi reaction with ketones

(2008) Suvi T.M. Simila et al.   TETRAHEDRON LETTERS

Organocatalysed asymmetric Mannich reactions

(2007) Jorge M. M. Verkade et al.   CHEMICAL SOCIETY REVIEWS