Transition-Metal-Catalyzed Hydroamination and Carboamination Reactions of Anthranilic Allenamides as a Route to 2-Vinyl- and 2-(α-Styryl)quinazolin-4-one Derivatives

PTEN/PI3K pathway as a therapeutic target for allergic airways inflammation

(2015) S.J. Park et al.   DRUGS OF THE FUTURE

Palladium(II)/Copper Halide/Solvent Combination for Selective Intramolecular Domino Reactions of Indolecarboxylic Acid Allylamides: An Unprecedented Arylation/Esterification Sequence

(2012) Gianluigi Broggini et al.   ADVANCED SYNTHESIS & CATALYSIS

Intramolecular Palladium-Catalyzed Aminocarboxylation of Olefins as a Direct Route to Bicyclic Oxazolidinones

(2011) Elena Borsini et al.   ADVANCED SYNTHESIS & CATALYSIS

Gold-Catalyzed Hydroamination of Alkynes and Allenes with Parent Hydrazine

(2011) Rei Kinjo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An efficient and practical entry to 2-amido-dienes and 3-amido-trienes from allenamides through stereoselective 1,3-hydrogen shifts

(2011) Ryuji Hayashi et al.   Beilstein Journal of Organic Chemistry

Gold-Catalyzed Nucleophilic Cyclization of Functionalized Allenes: A Powerful Access to Carbo- and Heterocycles

(2011) Norbert Krause et al.   CHEMICAL REVIEWS

Enantioselective Total Synthesis of (+)-Lysergic Acid, (+)-Lysergol, and (+)-Isolysergol by Palladium-Catalyzed Domino Cyclization of Allenes Bearing Amino and Bromoindolyl Groups

(2011) Shinsuke Inuki et al.   JOURNAL OF ORGANIC CHEMISTRY

Oppolzer-Type Intramolecular Diels–Alder Cycloadditions via Isomerizations of Allenamides

(2011) John B. Feltenberger et al.   ORGANIC LETTERS

Intramolecular Oxidative Pd(II)-Catalyzed Alkoxylation of 3-Aza-5-alkenols with O2 as Sole Oxidant: Mild Conditions for the Synthesis of 1,4-Oxazine Derivatives

(2011) Gianluigi Broggini et al.   SYNLETT

Cellulose-SO3H: an efficient and biodegradable solid acid for the synthesis of quinazolin-4(1H)-ones

(2011) B.V. Subba Reddy et al.   TETRAHEDRON LETTERS

Enantiopure 2-piperidylacetaldehyde as a useful building block in the diversity-oriented synthesis of polycyclic piperidine derivatives

(2011) Elena Borsini et al.   TETRAHEDRON-ASYMMETRY

Design, synthesis and evaluation of novel 2-thiophen-5-yl-3H-quinazolin-4-one analogues as inhibitors of transcription factors NF-кB and AP-1 mediated transcriptional activation: Their possible utilization as anti-inflammatory and anti-cancer agents

(2010) Rajan S. Giri et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Identification of novel quinazolin-4(3H)-ones as inhibitors of thermolysin, the prototype of the M4 family of proteinases

(2010) Mahmud Tareq Hassan Khan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

PI3K Inhibitors in Cardiovascular Disease

(2010) Andreas Eisenreich et al.   Cardiovascular Therapeutics

Platinum(ii)-catalyzed intermolecular hydroamination of monosubstituted allenes with secondary alkylamines

(2010) Kristina L. Toups et al.   CHEMICAL COMMUNICATIONS

Allenes as Three-Carbon Units in Catalytic Cycloadditions: New Opportunities with Transition-Metal Catalysts

(2010) Fernando López et al.   CHEMISTRY-A EUROPEAN JOURNAL

PI3K/Akt Signalling Pathway Specific Inhibitors: A Novel Strategy to Sensitize Cancer Cells to Anti-Cancer Drugs

(2010) Marco Falasca   CURRENT PHARMACEUTICAL DESIGN

Access to a Novel Class of Tetracyclic 1,4-Benzodiazepin-5-ones Starting from α-Amino Acids by Pd-Catalyzed Amination/1,3-Dipolar Cycloaddition as the Key Steps

(2010) Luca Basolo et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Potential role of PI3K inhibitors in the treatment of breast cancer

(2010) Sílvia Carvalho et al.   Future Oncology

Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-SelectiveN-Methyl-d-aspartate Receptor Antagonists

(2010) Cara A. Mosley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Tunable Pd-Catalyzed Cyclization of Indole-2-carboxylic Acid Allenamides: Carboamination vs Microwave-Assisted Hydroamination

(2010) Egle M. Beccalli et al.   JOURNAL OF ORGANIC CHEMISTRY

An Intermolecular Hydroamination of Allenamides with Arylamines Catalyzed by Cationic Au(I) Salts

(2010) Anthony W. Hill et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-catalyzed C–N bond formation via direct C–H bond functionalization. Recent developments in heterocyclic synthesis

(2010) Egle M. Beccalli et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Gold(I)-catalyzed enantioselective intramolecular hydroamination of allenes with ureas

(2010) Hao Li et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Torquoselective Ring Closures of Chiral Amido Trienes Derived from Allenamides. A Tandem Allene Isomerization−Pericyclic Ring-Closure−Intramolecular Diels−Alder Cycloaddition

(2010) Ryuji Hayashi et al.   ORGANIC LETTERS

A Facile and Mild Synthesis of Enamides using a Gold-Catalyzed Nucleophilic Addition to Allenamides

(2010) Marc C. Kimber   ORGANIC LETTERS

Synthesis and biological evaluation of febrifugine analogues as potential antimalarial agents

(2009) Shuren Zhu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Efficient synthesis of 2,3-dihydro-1H-pyrazoles via a highly selective Pd(0)-catalyzed coupling-cyclization reaction of terminal 2-substituted 2,3-allenyl hydrazines with aryl iodides

(2009) Xin Cheng et al.   CHEMICAL COMMUNICATIONS

Exploiting [2+2] cycloaddition chemistry: achievements with allenes

(2009) Benito Alcaide et al.   CHEMICAL SOCIETY REVIEWS

Phosphine-Free Palladium-Catalyzed Allene Carbopalladation/Allylic Alkylation Domino Sequence: A New Route to 4-(α-Styryl) γ-Lactams

(2009) Claire Kammerer et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed Intramolecular Hydroamination of Allenes Coupled to Aerobic Alcohol Oxidation

(2009) Shuifa Qiu et al.   CHEMISTRY-A EUROPEAN JOURNAL

σ-Alkylpalladium Intermediates in Intramolecular Heck Reactions:Isolation and Catalytic Activity

(2009) Egle M. Beccalli et al.   CHEMISTRY-A EUROPEAN JOURNAL

Allenes as Dipolarophiles and 1,3-Dipole Precursors: Synthesis of Carbocyclic and Heterocyclic Compounds

(2009) Teresa Pinho e Melo   CURRENT ORGANIC CHEMISTRY

Synthesis of Benzazepines by Gold-Catalysed Reactions ofN-Allenylamides

(2009) Álvaro González-Gómez et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Silver and Gold Catalysis for Cycloisomerization Reactions

(2009) Philippe Belmont et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Novel inhibitors of the PI3K family

(2009) Amancio Carnero   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Role of phosphoinositide 3-kinase p110δ in TLR4- and TLR9-mediated B cell cytokine production and differentiation

(2009) Nyla Dil et al.   MOLECULAR IMMUNOLOGY

A Novel Synthesis of 1,3-Oxazine-2,4-diones via a Simple and Efficient Reaction of CO2with 2,3-Allenamides

(2009) Guofei Chen et al.   ORGANIC LETTERS

Palladium-Catalyzed Domino Carbopalladation/5-exo-Allylic Amination of α-Amino Allenamides: An Efficient Entry to Enantiopure Imidazolidinones

(2009) Egle M. Beccalli et al.   ORGANIC LETTERS

Gold-Catalyzed Intermolecular Markovnikov Hydroamination of Allenes with Secondary Amines

(2009) Xiaoming Zeng et al.   ORGANIC LETTERS

Thermal Intramolecular [4 + 2] Cycloadditions of Allenamides: A Stereoselective Tandem Propargyl Amide Isomerization−Cycloaddition

(2009) Andrew G. Lohse et al.   ORGANIC LETTERS

Efficient palladium-catalyzed direct arylation of azines and diazines using ligand-free conditions

(2009) Luca Basolo et al.   TETRAHEDRON

Entry to nitrogen-containing heterocycles by based-promoted heterocyclization on allenylamides of l-α-aminoacids

(2009) Gianluigi Broggini et al.   TETRAHEDRON LETTERS

Gold-catalyzed intramolecular hydroamination of α-amino allenamides as a route to enantiopure 2-vinylimidazolidinones

(2009) Angelo M. Manzo et al.   TETRAHEDRON LETTERS

Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide–isozyme II adduct

(2008) Claudia Temperini et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Palladium-catalysed biscyclisation of allenic bromoalkenes through a zipper-mode cascade

(2008) Akinori Okano et al.   CHEMICAL COMMUNICATIONS

Transition metal-catalyzed three-component coupling of allenes and the related allylation reactions

(2008) Masilamani Jeganmohan et al.   CHEMICAL COMMUNICATIONS

Palladium-Catalyzed Coupling Reactions of Diarylvinylidenecyclopropanes with 2-Iodophenol andN-(2-Iodophenyl)-4-methylbenzenesulfonamide

(2008) Wei Li et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Carbonic anhydrase inhibitors. Sulfonamide diuretics revisited—old leads for new applications?

(2008) Claudia Temperini et al.   ORGANIC & BIOMOLECULAR CHEMISTRY