Quantifying SV2A density and drug occupancy in the human brain using [11C]UCB-J PET imaging and subcortical white matter as reference tissue

Kinetic evaluation and test–retest reproducibility of [11C]UCB-J, a novel radioligand for positron emission tomography imaging of synaptic vesicle glycoprotein 2A in humans

(2017) Sjoerd J Finnema et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Pharmacokinetic modeling of [11C]flumazenil kinetics in the rat brain

(2017) Isadora Lopes Alves et al.   EJNMMI Research

Synthesis and Preclinical Evaluation of 11C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain

(2016) N. B. Nabulsi et al.   JOURNAL OF NUCLEAR MEDICINE

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

Imaging synaptic density in the living human brain

(2016) Sjoerd J. Finnema et al.   Science Translational Medicine

Biodistribution and Radiation Dosimetry for the Novel SV2A Radiotracer [18F]UCB-H: First-in-Human Study

(2015) F. Bretin et al.   MOLECULAR IMAGING AND BIOLOGY

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

(2014) Guomei Tang et al.   NEURON

Quantification of 18F-JNJ-42259152, a Novel Phosphodiesterase 10A PET Tracer: Kinetic Modeling and Test-Retest Study in Human Brain

(2013) K. Van Laere et al.   JOURNAL OF NUCLEAR MEDICINE

Expression pattern of synaptic vesicle protein 2 (SV2) isoforms in patients with temporal lobe epilepsy and hippocampal sclerosis

(2013) J. Crèvecœur et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Decreased expression of synapse-related genes and loss of synapses in major depressive disorder

(2012) Hyo Jung Kang et al.   NATURE MEDICINE

Quantitative analysis of [18F]FDDNP PET using subcortical white matter as reference region

(2009) Koon-Pong Wong et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Measuring Drug Occupancy in the Absence of a Reference Region: The Lassen Plot Re-Visited

(2009) Vincent J Cunningham et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Down-regulation Synaptic Vesicle Protein 2A in the Anterior Temporal Neocortex of Patients with Intractable Epilepsy

(2009) Guibo Feng et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Model selection for time-activity curves: The corrected Akaike information criterion and the F-test

(2009) Peter Kletting et al.   Zeitschrift fur Medizinische Physik