Control of tissue-localized immune responses by human regulatory T cells

Surface expression of CD39 identifies an enriched Treg-cell subset in the rheumatic joint, which does not suppress IL-17A secretion

(2014) Jessica Herrath et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulatory T cells in systemic lupus erythematosus

(2014) Kim Ohl et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Memory regulatory T cells reside in human skin

(2014) Robert Sanchez Rodriguez et al.   JOURNAL OF CLINICAL INVESTIGATION

Isoform-Specific Inhibition of ROR -Mediated Transcriptional Activation by Human FOXP3

(2014) J. Du et al.   JOURNAL OF IMMUNOLOGY

Hypomethylation at the Regulatory T Cell–Specific Demethylated Region in CD25hiT Cells Is Decoupled from FOXP3 Expression at the Inflamed Site in Childhood Arthritis

(2014) David Bending et al.   JOURNAL OF IMMUNOLOGY

Comparative analysis of FoxP3+ regulatory T cells in the target tissues and blood in chronic graft versus host disease

(2014) M M Imanguli et al.   LEUKEMIA

Single Cell Tracking of Gadolinium Labeled CD4+ T Cells by Laser Ablation Inductively Coupled Plasma Mass Spectrometry

(2013) Amy J. Managh et al.   ANALYTICAL CHEMISTRY

CD161 defines the subset of FoxP3+ T cells capable of producing proinflammatory cytokines

(2013) A. M. Pesenacker et al.   BLOOD

Multiparameter single-cell profiling of human CD4+FOXP3+ regulatory T-cell populations in homeostatic conditions and during graft-versus-host disease

(2013) S. Dong et al.   BLOOD

A Special Population of Regulatory T Cells Potentiates Muscle Repair

(2013) Dalia Burzyn et al.   CELL

Single-cell mass cytometry for analysis of immune system functional states

(2013) Zach B Bjornson et al.   CURRENT OPINION IN IMMUNOLOGY

CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner

(2013) Behdad Afzali et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T regulatory cells in childhood arthritis – novel insights

(2013) Anne M. Pesenacker et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Canonical Wnt Signaling Negatively Modulates Regulatory T Cell Function

(2013) Jorg van Loosdregt et al.   IMMUNITY

Immunohistochemical analysis of FOXP3+ regulatory T cells in healthy human skin and autoimmune dermatoses

(2013) Sarah Terras et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Increased plasmacytoid dendritic cells and RORγt-expressing immune effectors in cutaneous acute graft-versus-host disease

(2013) Florent Malard et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Regulatory T cells in nonlymphoid tissues

(2013) Dalia Burzyn et al.   NATURE IMMUNOLOGY

Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis

(2013) Hong Nie et al.   NATURE MEDICINE

Bronchiolitis Obliterans Syndrome: The Achilles' Heel of Lung Transplantation

(2013) Ariss DerHovanessian et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

FOXP3+T Regulatory Cell Modifications in Inflammatory Bowel Disease Patients Treated with Anti-TNFαAgents

(2013) Luisa Guidi et al.   Biomed Research International

A novel function for FOXP3 in humans: intrinsic regulation of conventional T cells

(2012) A. N. McMurchy et al.   BLOOD

Targeting IL-17 in psoriasis: From cutaneous immunobiology to clinical application

(2012) Maria-Eugenia Ariza et al.   CLINICAL IMMUNOLOGY

T cell tolerance and immunity to commensal bacteria

(2012) Katherine M Nutsch et al.   CURRENT OPINION IN IMMUNOLOGY

Paradoxically Increased FOXP3+ T Cells in IBD Do Not Preferentially Express the Isoform of FOXP3 Lacking Exon 2

(2012) James D. Lord et al.   DIGESTIVE DISEASES AND SCIENCES

Regulatory T-cell therapy for inflammatory bowel disease: more questions than answers

(2012) Megan E. Himmel et al.   IMMUNOLOGY

TH17, TH22 and TReg Cells Are Enriched in the Healthy Human Cecum

(2012) Martin J. Wolff et al.   PLoS One

A Model for Personalized in Vivo Analysis of Human Immune Responsiveness

(2012) H. Kalscheuer et al.   Science Translational Medicine

Regulatory T Cells Inhibit CD8+ T-Cell Tissue Invasion in Human Skin Graft-Versus-Host Reactions

(2012) Emily Mavin et al.   TRANSPLANTATION

Regulation of epithelial immunity by IL-17 family cytokines

(2012) Rajita Pappu et al.   TRENDS IN IMMUNOLOGY

Regulatory T cell migration during an immune response

(2012) Yaozhong Ding et al.   TRENDS IN IMMUNOLOGY

TH17 Cells in Autoimmunity and Immunodeficiency: Protective or Pathogenic?

(2012) Ashish K. Marwaha et al.   Frontiers in Immunology

Impaired suppression of synovial fluid CD4+CD25− T cells from patients with juvenile idiopathic arthritis by CD4+CD25+ Treg cells

(2011) Susanne Haufe et al.   ARTHRITIS AND RHEUMATISM

Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells

(2011) E. J. Wehrens et al.   BLOOD

Human tumor-infiltrating Th17 cells have the capacity to differentiate into IFN-γ+ and FOXP3+ T cells with potent suppressive function

(2011) Jian Ye et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Suppression assays with human T regulatory cells: A technical guide

(2011) Alicia N. McMurchy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The effects of commensal microbiota on immune cell subsets and inflammatory responses

(2011) Takatoshi Chinen et al.   IMMUNOLOGICAL REVIEWS

Restoring the regulatory regime in IBD: Do anti-TNF agents rescue treg?

(2011) Zaid Heetun et al.   INFLAMMATORY BOWEL DISEASES

Cutting Edge: Immunological Consequences and Trafficking of Human Regulatory Macrophages Administered to Renal Transplant Recipients

(2011) J. A. Hutchinson et al.   JOURNAL OF IMMUNOLOGY

IL-17 + Regulatory T Cells in the Microenvironments of Chronic Inflammation and Cancer

(2011) Ilona Kryczek et al.   JOURNAL OF IMMUNOLOGY

CD4+FOXP3+ T Regulatory Cells in Human Autoimmunity: More Than a Numbers Game

(2011) S. A. Long et al.   JOURNAL OF IMMUNOLOGY

Foxp3+ Regulatory T Cells of Psoriasis Patients Easily Differentiate into IL-17A-Producing Cells and Are Found in Lesional Skin

(2011) H. Jorn Bovenschen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Control of TH17 cells occurs in the small intestine

(2011) Enric Esplugues et al.   NATURE

Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease

(2011) Margarita Dominguez-Villar et al.   NATURE MEDICINE

Resident Memory T Cells (TRM) Are Abundant in Human Lung: Diversity, Function, and Antigen Specificity

(2011) Rahul Purwar et al.   PLoS One

Biologic predictors of extension of oligoarticular juvenile idiopathic arthritis as determined from synovial fluid cellular composition and gene expression

(2010) Patricia J. Hunter et al.   ARTHRITIS AND RHEUMATISM

Cutaneous GVHD is associated with the expansion of tissue-localized Th1 and not Th17 cells

(2010) R. Broady et al.   BLOOD

Increased Airway T Regulatory Cells in Asthmatic Subjects

(2010) Lucy J.C. Smyth et al.   CHEST

Isolation of intact genomic DNA from FOXP3-sorted human regulatory T cells for epigenetic analyses

(2010) Leo Hansmann et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Impaired function of regulatory T-cells in hypersensitivity pneumonitis

(2010) M. Girard et al.   EUROPEAN RESPIRATORY JOURNAL

Characterization of Interleukin-17–Producing Regulatory T Cells in Inflamed Intestinal Mucosa From Patients With Inflammatory Bowel Diseases

(2010) Zaruhi Hovhannisyan et al.   GASTROENTEROLOGY

Protection against Bronchiolitis Obliterans Syndrome Is Associated with Allograft CCR7+CD45RA− T Regulatory Cells

(2010) Aric L. Gregson et al.   PLoS One

Elevated mRNA levels of CTLA-4, FoxP3, and Granzyme B in BAL, but not in blood, during acute rejection of lung allografts

(2010) Caroline B. Madsen et al.   TRANSPLANT IMMUNOLOGY

Decreased Percentage of CD4+FoxP3+ Cells in Bronchoalveolar Lavage From Lung Transplant Recipients Correlates With Development of Bronchiolitis Obliterans Syndrome

(2010) Sangeeta M. Bhorade et al.   TRANSPLANTATION

Increase in FOXP3+ Regulatory T Cells in GVHD Skin Biopsies Is Associated with Lower Disease Severity and Treatment Response

(2009) Cristina Fondi et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

IL-17-producing human peripheral regulatory T cells retain suppressive function

(2009) G. Beriou et al.   BLOOD

Quantitative DNA Methylation Analysis of FOXP3 as a New Method for Counting Regulatory T Cells in Peripheral Blood and Solid Tissue

(2009) G. Wieczorek et al.   CANCER RESEARCH

Increased Th17 cells are accompanied by FoxP3+ Treg cell accumulation and correlated with psoriasis disease severity

(2009) Li Zhang et al.   CLINICAL IMMUNOLOGY

A Dual Action of Rheumatoid Arthritis Synovial Fibroblast IL-15 Expression on the Equilibrium between CD4+CD25+ Regulatory T Cells and CD4+CD25- Responder T Cells

(2009) M. Benito-Miguel et al.   JOURNAL OF IMMUNOLOGY

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

(2009) Meghan A Koch et al.   NATURE IMMUNOLOGY

Dynamics of Human Regulatory T Cells in Lung Lavages of Lung Transplant Recipients

(2009) David C. Neujahr et al.   TRANSPLANTATION

Interleukin-17–producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers

(2008) Kiran Nistala et al.   ARTHRITIS AND RHEUMATISM

The kinetics of CD4+Foxp3+ T cell accumulation during a human cutaneous antigen-specific memory response in vivo

(2008) Milica Vukmanovic-Stejic et al.   JOURNAL OF CLINICAL INVESTIGATION