Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells

Th1, Th2, and Th17 Effector T Cell-Induced Autoimmune Gastritis Differs in Pathological Pattern and in Susceptibility to Suppression by Regulatory T Cells

(2014) G. H. Stummvoll et al.   JOURNAL OF IMMUNOLOGY

The Effector T Cells of Diabetic Subjects Are Resistant to Regulation via CD4+FOXP3+ Regulatory T Cells

(2014) A. Schneider et al.   JOURNAL OF IMMUNOLOGY

Autoimmunity in Dry Eye Is Due to Resistance of Th17 to Treg Suppression

(2014) S. K. Chauhan et al.   JOURNAL OF IMMUNOLOGY

Juvenile idiopathic arthritis

(2011) Berent Prakken et al.   LANCET

Regulatory T cells overturned: the effectors fight back

(2009) Lucy S. K. Walker   IMMUNOLOGY

Protein Kinase B/Akt Signals Impair Th17 Differentiation and Support Natural Regulatory T Cell Function and Induced Regulatory T Cell Formation

(2009) M. Pierau et al.   JOURNAL OF IMMUNOLOGY

Reduced CD4+,CD25− T cell sensitivity to the suppressive function of CD4+,CD25high,CD127−/lowregulatory T cells in patients with active systemic lupus erythematosus

(2008) Ram Kumar Chowdary Venigalla et al.   ARTHRITIS AND RHEUMATISM

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

(2008) H. J. P. M. Koenen et al.   BLOOD

Human regulatory T cells: role in autoimmune disease and therapeutic opportunities

(2008) Todd M. Brusko et al.   IMMUNOLOGICAL REVIEWS

The AKT–mTOR axis regulates de novo differentiation of CD4+Foxp3+cells

(2008) Sokol Haxhinasto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors

(2008) A. M. D'Alise et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR

(2008) S. Sauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distribution and clinical significance of blood dendritic cells in children with juvenile idiopathic arthritis

(2007) E Smolewska et al.   ANNALS OF THE RHEUMATIC DISEASES