Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis

Unconventional secretion of Acb1 is mediated by autophagosomes

(2010) Juan M. Duran et al.   JOURNAL OF CELL BIOLOGY

Atheroembolic renal disease

(2010) Francesco Scolari et al.   LANCET

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One

Inflammation, oxidative stress and lipids: the risk triad for atherosclerosis in gout

(2010) E. Krishnan   RHEUMATOLOGY

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

Generation and Biological Activities of Oxidized Phospholipids

(2009) Valery N. Bochkov et al.   ANTIOXIDANTS & REDOX SIGNALING

Activation of Nrf2 in Endothelial Cells Protects Arteries From Exhibiting a Proinflammatory State

(2009) Mustafa Zakkar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inflammasome-dependent Caspase-1 Activation in Cervical Epithelial Cells Stimulates Growth of the Intracellular PathogenChlamydia trachomatis

(2009) Ali A. Abdul-Sater et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Role of Inflammation in Atherosclerosis Associated with Rheumatoid Arthritis

(2008) Peter Libby   AMERICAN JOURNAL OF MEDICINE

Active Caspase-1 Is a Regulator of Unconventional Protein Secretion

(2008) Martin Keller et al.   CELL

Critical Role of Bone Marrow Apoptosis-Associated Speck-Like Protein, an Inflammasome Adaptor Molecule, in Neointimal Formation After Vascular Injury in Mice

(2008) Noriyuki Yajima et al.   CIRCULATION

Peroxiredoxin1 Prevents Excessive Endothelial Activation and Early Atherosclerosis

(2008) Janka Kisucka et al.   CIRCULATION RESEARCH

Nrf2 Regulates Antioxidant Gene Expression Evoked by Oxidized Phospholipids in Endothelial Cells and Murine Arteries In Vivo

(2008) Henna-Kaisa Jyrkkänen et al.   CIRCULATION RESEARCH

Active immunization with IL-1 displayed on virus-like particles protects from autoimmune arthritis

(2008) Gunther Spohn et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Hemoxygenase-1 in Cardiovascular Disease

(2008) Naglaa K. Idriss et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Translating molecular discoveries into new therapies for atherosclerosis

(2008) Daniel J. Rader et al.   NATURE

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Disruption of Nrf2, a Key Inducer of Antioxidant Defenses, Attenuates ApoE-Mediated Atherosclerosis in Mice

(2008) Thomas E. Sussan et al.   PLoS One