Article
Biophysics
Liu Miao, Liu Daozhou, Cheng Ying, Mei Qibing, Zhou Siyuan
Summary: Preparation of RES-loaded nanostructured lipid carrier gel (RES-NLC-gel) improved RES stability and accumulation in the epidermis. The gel effectively scavenged free radicals, protected skin cells from UV radiation, decreased expression of apoptotic proteins, and increased expression of survival proteins. Pretreatment with RES-NLC-gel reduced erythema, wrinkles, and scabs on mouse skin, decreased epidermal thickness, and increased antioxidant enzyme activities in skin tissue. RES-NLC-gel demonstrated significant anti-UV irradiation and antioxidant activity in vivo, showing great potential in skin protection.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Review
Biochemistry & Molecular Biology
Jaeeun Lee, Min-Hyun Kim, Hyeyoung Kim
Summary: A moderate amount of ROS plays an important role in cell signaling and immune response, while excessive production can lead to inflammation and pathological conditions. The gastrointestinal mucosa is continuously exposed to ROS, increasing the risk of GI disorders. AST, a compound with antioxidant and anti-inflammatory properties, has shown protective effects against GI diseases through various mechanisms, including ROS neutralization, enhancement of antioxidant enzyme activity, and suppression of inflammation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Medicine, Research & Experimental
Acharya Balkrishna, Vivek Gohel, Nishit Pathak, Rani Singh, Meenu Tomer, Malini Rawat, Rishabh Dev, Anurag Varshney
Summary: Atherosclerosis is a major pathological process of cardiovascular diseases, which can begin early in life and remain silent before symptoms manifest. The formation of foamy macrophages due to dysregulated lipid metabolism is important in atherosclerotic plaque development. Current pharmacotherapy for atherosclerosis is limited, but "Lipidom" has shown potential with its antioxidant, lipid-lowering, and anti-inflammatory properties. This study aimed to characterize the pharmacological effects of "Lipidom" using experimental models.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Review
Medicine, Research & Experimental
Sepideh Bastani, Vahid Vahedian, Mohsen Rashidi, Amirabbas Mir, Sepideh Mirzaei, Iraj Alipourfard, Farhad Pouremamali, Hamidreza Nejabati, Jamileh Kadkhoda, Nazila Fathi Maroufi, Maryam Akbarzadeh
Summary: This review article provides a comprehensive overview of the antioxidant and anti-inflammatory effects of Crocin in various diseases and tissues. It highlights the potential of Crocin in the treatment of cardiovascular disease, cancer, diabetes, and kidney disease, as well as its role in the COVID-19 pandemic.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Food Science & Technology
Li-You Chen, Hsin-Lin Cheng, Chih-Kai Liao, Yu-Hsiang Kuan, Tang-Jun Liang, To-Jung Tseng, Hsing-Chun Lin
Summary: The aim of this study is to explore the potential anti-oxidant and anti-inflammatory mechanisms of luteolin in the treatment of diabetic nephropathy. Luteolin significantly reduced blood glucose and BUN levels in diabetic rats and increased serum sodium and chloride levels. Moreover, luteolin inhibited the activation of PI3K/Akt signaling pathway and the expressions of its downstream apoptosis-related proteins.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Article
Biochemistry & Molecular Biology
Weiling Lu, Changchang Kong, Shijunyin Cheng, Xiaodong Xu, Jianfa Zhang
Summary: The study shows that riclin can protect the skin from UVB-induced damage, with antioxidant and anti-inflammatory effects. Riclin increases collagen expression and inhibits oxidation and melanin synthesis. In vivo experiments on mice demonstrate that riclin effectively reduces UVB-induced skin damage and suppresses inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Jelica Grujic-Milanovic, Vesna Jacevic, Zoran Miloradovic, Djurdjica Jovovic, Ivica Milosavljevic, Sladjan D. Milanovic, Nevena Mihailovic-Stanojevic
Summary: Resveratrol significantly reduces blood pressure in hypertensive animals, improves cardiac tissue morphology, decreases the presence of TGF-beta and Bax in cardiac myocytes, and suppresses lipid peroxidation, indicating its potential in preventing hypertrophic and apoptotic consequences induced by high blood pressure, especially in malignant hypertension.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Oncology
Hossein Moutabian, Mehrsa Majdaeen, Ruhollah Ghahramani-Asl, Masoumeh Yadollahi, Esmaeil Gharepapagh, Gholamreza Ataei, Zahra Falahatpour, Hamed Bagheri, Bagher Farhood
Summary: This study aimed to review the potential therapeutic effects of resveratrol in combination with 5-fluorouracil (5-FU) against colorectal cancer. The results demonstrated that co-administration of resveratrol could sensitize the colorectal cancer cells to 5-FU treatment via various mechanisms.
CANCER CELL INTERNATIONAL
(2022)
Article
Engineering, Biomedical
Keke Wu, Meimei Fu, Yitao Zhao, Ethan Gerhard, Yue Li, Jian Yang, Jinshan Guo
Summary: This study developed a multifunctional bioadhesive made from the natural polyphenolic compound tannic acid, which possesses antioxidant, anti-inflammatory, and antimicrobial properties. The bioadhesive showed favorable biocompatibility and mechanical strength, and it promoted wound closure and scarless healing.
BIOACTIVE MATERIALS
(2023)
Article
Food Science & Technology
Florence Malongane, Lyndy Joy McGaw, Oyinlola Oluwunmi Olaokun, Fhatuwani Nixwell Mudau
Summary: South Africa is known for its various herbal teas with antioxidant, anti-inflammatory and anti-diabetic properties. This study investigated the antioxidant activity, anti-inflammatory effects, and anti-diabetic properties of selected tea blends. The results showed that special tea and its blend with bush tea exhibited potent antioxidant and anti-inflammatory activity, and blending increased the antioxidant activity. All the tea samples also showed anti-diabetic effects, although less potent than insulin. The findings support the use of blended herbal teas and suggest further research on the anti-inflammatory effects of special tea.
Review
Biochemistry & Molecular Biology
Anastasia V. Poznyak, Dwaipayan Bharadwaj, Gauri Prasad, Andrey V. Grechko, Margarita A. Sazonova, Alexander N. Orekhov
Summary: Atherosclerosis is a well-known global health problem with unclear pathogenesis. Inflammation is considered the preferred target for its treatment, with studies showing efficacy in animal models but inconclusive results in clinical studies. Anti-inflammatory therapy could be part of a complex treatment for atherosclerosis prevention.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Food Science & Technology
Shuai Zong, Helin Wang, Jinglei Li, Jun Liu, Changhai Jin
Summary: Zhuke-Hulu tea showed significant anti-oxidant activity by enhancing endogenous anti-oxidant defense system and Nrf2 nuclear translocation, and exhibited anti-inflammatory efficiency by down-regulating protein levels of iNOS and COX-2 as well as production of pro-inflammatory cytokines. Additionally, it alleviated intestinal inflammation by reducing pro-inflammatory cytokines levels, inhibiting inflammatory cell infiltration, and modulating gut microbiota.
Article
Biochemistry & Molecular Biology
Ming-Cheng Lin, Chien-Chi Liu, Yu-Chen Lin, Chin-Sheng Liao
Summary: Cerebral ischemia is associated with increased oxidative stress, which can be mitigated by resveratrol's anti-oxidant and anti-inflammatory properties. Overload of transition elements and toxic metals like iron, copper, aluminum, and arsenic are detrimental to brain function. Resveratrol protects against cerebral ischemic injury by reducing lipid peroxidation, transitioning elements, and toxic metals, while enhancing anti-oxidant activity.
Article
Food Science & Technology
Bo-sai He, Xiao Wang, Ying Zhang, Cheng Gao, Cheng-kai Wu, Si-rui Guo, Yan-ting Gu, Qing Li, Jia-hong Wang
Summary: The seeds of Moringa oleifera Lam have renal protective effects in diabetic nephropathy by modulating multiple signaling pathways, exerting anti-inflammatory, anti-fibrosis, and anti-oxidative effects.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Review
Biochemistry & Molecular Biology
Tiantian Meng, Dingfu Xiao, Arowolo Muhammed, Juying Deng, Liang Chen, Jianhua He
Summary: Resveratrol, a natural phytoalexin polyphenol, demonstrates antioxidant, anti-inflammatory, and anti-carcinogenic properties, with the ability to modulate inflammatory responses and exhibit immunomodulatory function both in vivo and in vitro.
Article
Nutrition & Dietetics
Nicholas R. Fuller, Ian D. Caterson, Amanda Sainsbury, Gareth Denyer, Mackenzie Fong, James Gerofi, Katherine Baqleh, Kathryn H. Williams, Namson S. Lau, Tania P. Markovic
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2015)
Review
Food Science & Technology
Youngjoo Kwon
FOOD REVIEWS INTERNATIONAL
(2016)
Article
Nutrition & Dietetics
Martha Nydia Ballesteros, Fabrizio Valenzuela, Alma E. Robles, Elizabeth Artalejo, David Aguilar, Catherine J. Andersen, Herlindo Valdez, Maria Luz Fernandez
Review
Cardiac & Cardiovascular Systems
Helena Gylling, Jogchum Plat, Stephen Turley, Henry N. Ginsberg, Lars Ellegard, Wendy Jessup, Peter J. Jones, Dieter Luetjohann, Winfried Maerz, Luis Masana, Guenther Silbernagel, Bart Staels, Jan Boren, Alberico L. Catapano, Guy De Backer, John Deanfield, Olivier S. Descamps, Petri T. Kovanen, Gabriele Riccardi, Lale Tokgozoglu, M. John Chapman
Review
Physiology
Marie O. Fosbol, Bo Zerahn
CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING
(2015)
Article
Endocrinology & Metabolism
[Anonymous]
Article
Biochemistry & Molecular Biology
Todd C. Rideout, Vanu Ramprasath, John D. Griffin, Richard W. Browne, Scott V. Harding, Peter J. H. Jones
LIPIDS IN HEALTH AND DISEASE
(2014)
Article
Food Science & Technology
Mandana Amir Shaghaghi, Scott V. Harding, Peter J. H. Jones
JOURNAL OF FUNCTIONAL FOODS
(2014)
Article
Nutrition & Dietetics
Rogelio Gonzalez-Arellanes, Rene Urquidez-Romero, Alejandra Rodriguez-Tadeo, Julian Esparza-Romero, Rosa Olivia Mendez-Estrada, Erik Ramirez-Lopez, Alma Elizabeth Robles-Sardin, Bertha Isabel Pacheco-Moreno, Heliodoro Aleman-Mateo
Summary: Densitometry, hydrometry, and DXA methods cannot be interchangeably applied with the 4C model for assessing fat mass in obese older Hispanic-American adults, and modifying the assumptions of densitometry and hydrometry equations can improve bias.
CLINICAL NUTRITION
(2021)
Article
Medicine, General & Internal
Mohammed T. Hudda, Jonathan C. K. Wells, Linda S. Adair, Jose R. A. Alvero-Cruz, Maxine N. Ashby-Thompson, Martha N. Ballesteros-Vasquez, Jesus Barrera-Exposito, Benjamin Caballero, Elvis A. Carnero, Geoff J. Cleghorn, Peter S. W. Davies, Malgorzata Desmond, Delan Devakumar, Dympna Gallagher, Elvia Guerrero-Alcocer, Ferdinand Haschke, Mary Horlick, Houda Ben Jemaa, Ashraful Khan, Amani Mankai, Makama A. Monyeki, Hilde L. Nashandi, Luis Ortiz-Hernandez, Guy Plasqui, Felipe F. Reichert, Alma E. Robles-Sardin, Elaine Rush, Roman J. Shypailo, Jakub G. Sobiecki, Gill A. ten Hoor, Jesus Valdes, V. Pujitha Wickramasinghe, William W. Wong, Richard D. Riley, Christopher G. Owen, Peter H. Whincup, Claire M. Nightingale
Summary: This study evaluated the performance of a UK based prediction model for estimating fat-free mass in children and adolescents in non-UK settings. The model showed good predictive ability in all countries, with high R2 values and good calibration. The model's performance was consistent across different genders, ages, ethnicities, and income groups.
BMJ-BRITISH MEDICAL JOURNAL
(2022)
Article
Agronomy
Alfonso A. Gardea-Bejar, Alberto Sanchez-Estrada, Jesus A. Orozco-Avitia, Martin E. Tiznado-Hernandez, Rosalba Troncoso-Rojas, Jorge N. Mercado-Ruiz, Angel J. Ojeda-Contreras, Judith Fortiz-Hernandez, Alma E. Robles-Sardin
Summary: In this experiment, isothermal microcalorimetry was used to objectively measure the quality loss of asparagus spears during postharvest storage. A regression analysis showed a determination coefficient of 0.79 and 0.87 between metabolic heat and respiration rate at 2 degrees C and 5 degrees C, respectively. Regression analysis also indicated a relationship between metabolic heat and fructose (0.5) and glucose (0.67) at 2 degrees C, as well as fructose (0.79) and glucose (0.76) at 5 degrees C. This method proved to be sensitive in detecting changes in postharvest parameters commonly used to evaluate asparagus spears quality.
NEW ZEALAND JOURNAL OF CROP AND HORTICULTURAL SCIENCE
(2023)
Article
Endocrinology & Metabolism
Rogelio Gonzalez-Arellanes, Rene Urquidez-Romero, Alejandra Rodriguez-Tadeo, Julian Esparza-Romero, Rosa Olivia Mendez-Estrada, Erik Ramirez-Lopez, Alma-Elizabeth Robles-Sardin, Bertha-Isabel Pacheco-Moreno, Heliodoro Aleman-Mateo
Summary: This study compared the fat-free mass component values of older Hispanic adults to cadaver reference values and found that certain factors can affect the density of fat-free mass and impact body composition estimations.
JOURNAL OF CLINICAL DENSITOMETRY
(2022)
Article
Endocrinology & Metabolism
Carine M. Lenders, Aaron J. Manders, Joanna E. Perdomo, Kathy A. Ireland, Sarah E. Barlow
CURRENT OBESITY REPORTS
(2016)
Article
Psychology, Clinical
Myra Altman, Denise E. Wilfley
JOURNAL OF CLINICAL CHILD AND ADOLESCENT PSYCHOLOGY
(2015)
Review
Psychology, Developmental
David M. Janicke, Ric G. Steele, Laurie A. Gayes, Crystal S. Lim, Lisa M. Clifford, Elizabeth M. Schneider, Julia K. Carmody, Sarah Westen
JOURNAL OF PEDIATRIC PSYCHOLOGY
(2014)