Gene expression and regulation in systemic lupus erythematosus

SAT0006 Microrna analysis of human lupus nephritis: Evidence for modulation of kallikrein 4 by MIR-422A

(2014) E. Krasoudaki et al.   ANNALS OF THE RHEUMATIC DISEASES

Circulating MicroRNA Expression Profiles Associated With Systemic Lupus Erythematosus

(2013) Anting Liu Carlsen et al.   ARTHRITIS AND RHEUMATISM

RNA-Seq for Enrichment and Analysis of IRF5 Transcript Expression in SLE

(2013) Rivka C. Stone et al.   PLoS One

Genome-wide profiling of target genes for the systemic lupus erythematosus-associated transcription factors IRF5 and STAT4

(2012) Chuan Wang et al.   ANNALS OF THE RHEUMATIC DISEASES

Identification of microRNA-31 as a novel regulator contributing to impaired interleukin-2 production in T cells from patients with systemic lupus erythematosus

(2012) Wei Fan et al.   ARTHRITIS AND RHEUMATISM

Decreased microRNA-142-3p/5p expression causes CD4+ T cell activation and B cell hyperstimulation in systemic lupus erythematosus

(2012) Shu Ding et al.   ARTHRITIS AND RHEUMATISM

RNA-Seq and human complex diseases: recent accomplishments and future perspectives

(2012) Valerio Costa et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genome, epigenome and transcriptome analyses of a pair of monozygotic twins discordant for systemic lupus erythematosus

(2012) Hiroshi Furukawa et al.   HUMAN IMMUNOLOGY

Genetic and epigenetic contribution to complex traits

(2012) H. Kilpinen et al.   HUMAN MOLECULAR GENETICS

Cross-Species Transcriptional Network Analysis Defines Shared Inflammatory Responses in Murine and Human Lupus Nephritis

(2012) C. C. Berthier et al.   JOURNAL OF IMMUNOLOGY

Taming lupus—a new understanding of pathogenesis is leading to clinical advances

(2012) Zheng Liu et al.   NATURE MEDICINE

Glomerular and tubulointerstitial miR-638, miR-198 and miR-146a expression in lupus nephritis

(2012) JIANXIN LU et al.   NEPHROLOGY

Associations between the Expression of Epigenetically Regulated Genes and the Expression of DNMTs and MBDs in Systemic Lupus Erythematosus

(2012) Eva Balada et al.   PLoS One

Molecular Characterization of Circulating Plasma Cells in Patients with Active Systemic Lupus Erythematosus

(2012) Patricia L. Lugar et al.   PLoS One

The genetics of lupus: a functional perspective

(2012) Sandra G Guerra et al.   ARTHRITIS RESEARCH & THERAPY

Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression

(2011) E. Stagakis et al.   ANNALS OF THE RHEUMATIC DISEASES

Meta-analysis of microarray data using a pathway-based approach identifies a 37-gene expression signature for systemic lupus erythematosus in human peripheral blood mononuclear cells

(2011) Dhivya Arasappan et al.   BMC Medicine

Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus

(2011) Matlock Jeffries et al.   Epigenetics

A whole genome methylation analysis of systemic lupus erythematosus: hypomethylation of the IL10 and IL1R2 promoters is associated with disease activity

(2011) S-Y Lin et al.   GENES AND IMMUNITY

cAMP-responsive Element Modulator α (CREMα) Suppresses IL-17F Protein Expression in T Lymphocytes from Patients with Systemic Lupus Erythematosus (SLE)

(2011) Christian M. Hedrich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

cAMP-responsive Element Modulator (CREM)α Protein Signaling Mediates Epigenetic Remodeling of the Human Interleukin-2 Gene

(2011) Christian M. Hedrich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Promoter Hypomethylation Results in Increased Expression of Protein Phosphatase 2A in T Cells from Patients with Systemic Lupus Erythematosus

(2011) Katsue Sunahori et al.   JOURNAL OF IMMUNOLOGY

Inflammasome Activation of IL-18 Results in Endothelial Progenitor Cell Dysfunction in Systemic Lupus Erythematosus

(2011) J. M. Kahlenberg et al.   JOURNAL OF IMMUNOLOGY

Mapping and analysis of chromatin state dynamics in nine human cell types

(2011) Jason Ernst et al.   NATURE

B Cell Signature during Inactive Systemic Lupus Is Heterogeneous: Toward a Biological Dissection of Lupus

(2011) Jean-Claude Garaud et al.   PLoS One

Underexpression of mitochondrial-DNA encoded ATP synthesis-related genes and DNA repair genes in systemic lupus erythematosus

(2011) Hooi-Ming Lee et al.   ARTHRITIS RESEARCH & THERAPY

Therapeutic opportunities in systemic lupus erythematosus: state of the art and prospects for the new decade

(2010) G. K. Bertsias et al.   ANNALS OF THE RHEUMATIC DISEASES

MicroRNA-125a contributes to elevated inflammatory chemokine RANTES levels via targeting KLF13 in systemic lupus erythematosus

(2010) Xia Zhao et al.   ARTHRITIS AND RHEUMATISM

Overexpression of the growth arrest and DNA damage-induced 45α gene contributes to autoimmunity by promoting DNA demethylation in lupus T cells

(2010) Yaping Li et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1

(2010) Sha Zhao et al.   ARTHRITIS AND RHEUMATISM

Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: up-regulation of the type I interferon system is strongly associated with vascular disease

(2010) C. Lood et al.   BLOOD

Hypomethylation ofIL10andIL13Promoters in CD4+T Cells of Patients with Systemic Lupus Erythematosus

(2010) Ming Zhao et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1

(2010) W. Pan et al.   JOURNAL OF IMMUNOLOGY

A CD8+ T cell transcription signature predicts prognosis in autoimmune disease

(2010) Eoin F McKinney et al.   NATURE MEDICINE

Genetic susceptibility to systemic lupus erythematosus in the genomic era

(2010) Yun Deng et al.   Nature Reviews Rheumatology

Identification of Unique MicroRNA Signature Associated with Lupus Nephritis

(2010) Jeannie L. Te et al.   PLoS One

Gene Network Analysis of Bone Marrow Mononuclear Cells Reveals Activation of Multiple Kinase Pathways in Human Systemic Lupus Erythematosus

(2010) Magdalene Nakou et al.   PLoS One

Novel expression signatures identified by transcriptional analysis of separated leucocyte subsets in systemic lupus erythematosus and vasculitis

(2009) P. A. Lyons et al.   ANNALS OF THE RHEUMATIC DISEASES

Interleukin-6 and type I interferon-regulated genes and chemokines mark disease activity in dermatomyositis

(2009) Hatice Bilgic et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

(2009) Yuanjia Tang et al.   ARTHRITIS AND RHEUMATISM

Interferon signature gene expression is correlated with autoantibody profiles in patients with incomplete lupus syndromes

(2009) Q.-Z. Li et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Global H4 acetylation analysis by ChIP-chip in systemic lupus erythematosus monocytes

(2009) Z Zhang et al.   GENES AND IMMUNITY

Recent insights into the genetic basis of systemic lupus erythematosus

(2009) K L Moser et al.   GENES AND IMMUNITY

Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

(2009) B. M. Javierre et al.   GENOME RESEARCH

Gene expression in systemic lupus erythematosus: Bone marrow analysis differentiates active from inactive disease and reveals apoptosis and granulopoiesis signatures

(2008) Magdalene Nakou et al.   ARTHRITIS AND RHEUMATISM

DNA methylation inhibition increases T cell KIR expression through effects on both promoter methylation and transcription factors

(2008) Ying Liu et al.   CLINICAL IMMUNOLOGY

Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients

(2008) A H Sawalha et al.   GENES AND IMMUNITY

Microarray Analysis of Glomerular Gene Expression in Murine Lupus Nephritis

(2008) Kae Teramoto et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Comprehensive analysis of microRNA expression patterns in renal biopsies of lupus nephritis patients

(2008) Yong Dai et al.   RHEUMATOLOGY INTERNATIONAL