RNA-Seq for Enrichment and Analysis of IRF5 Transcript Expression in SLE

Interferon regulatory factor 5 is critical for the development of lupus in MRL/lpr mice

(2011) Yoshifumi Tada et al.   ARTHRITIS AND RHEUMATISM

Interferon regulatory factor 5 activation in monocytes of systemic lupus erythematosus patients is triggered by circulating autoantigens independent of type I interferons

(2011) Rivka C. Stone et al.   ARTHRITIS AND RHEUMATISM

Identification of novel transcripts in annotated genomes using RNA-Seq

(2011) A. Roberts et al.   BIOINFORMATICS

Recent advances in the genetics of systemic lupus erythematosus

(2011) Donna L Thibault Flesher et al.   Expert Review of Clinical Immunology

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

Replication of GWAS-identified systemic lupus erythematosus susceptibility genes affirms B-cell receptor pathway signalling and strengthens the role of IRF5 in disease susceptibility in a Northern European population

(2011) T. M. Jarvinen et al.   RHEUMATOLOGY

Cis-regulation of IRF5 expression is unable to fully account for systemic lupus erythematosus association: analysis of multiple experiments with lymphoblastoid cell lines

(2011) Elisa Alonso-Perez et al.   ARTHRITIS RESEARCH & THERAPY

Haplotype and isoform specific expression estimation using multi-mapping RNA-seq reads

(2011) Ernest Turro et al.   GENOME BIOLOGY

Exon 6 variants carried on systemic lupus erythematosus (SLE) risk haplotypes modulate IRF5 function

(2010) Feng Wen et al.   AUTOIMMUNITY

Differential Requirement of Histone Acetylase and Deacetylase Activities for IRF5-Mediated Proinflammatory Cytokine Expression

(2010) D. Feng et al.   JOURNAL OF IMMUNOLOGY

Alternative expression analysis by RNA sequencing

(2010) Malachi Griffith et al.   NATURE METHODS

Genetic susceptibility to systemic lupus erythematosus in the genomic era

(2010) Yun Deng et al.   Nature Reviews Rheumatology

Apparent Non-Canonical Trans-Splicing Is Generated by Reverse Transcriptase In Vitro

(2010) Jonathan Houseley et al.   PLoS One

Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus

(2010) D. A. Savitsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gender-dependent Expression of Murine Irf5 Gene: Implications for Sex Bias in Autoimmunity

(2010) H. Shen et al.   Journal of Molecular Cell Biology

Association of IRF5 polymorphisms with activation of the interferon   pathway

(2009) O. J. Rullo et al.   ANNALS OF THE RHEUMATIC DISEASES

Statistical inferences for isoform expression in RNA-Seq

(2009) Hui Jiang et al.   BIOINFORMATICS

RNA-Seq gene expression estimation with read mapping uncertainty

(2009) Bo Li et al.   BIOINFORMATICS

Identifiability of isoform deconvolution from junction arrays and RNA-Seq

(2009) David Hiller et al.   BIOINFORMATICS

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

IFN Regulatory Factor 5 Is Required for Disease Development in the Fc RIIB-/-Yaa and Fc RIIB-/- Mouse Models of Systemic Lupus Erythematosus

(2009) C. Richez et al.   JOURNAL OF IMMUNOLOGY

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Association of the IRF5 risk haplotype with high serum interferon-α activity in systemic lupus erythematosus patients

(2008) Timothy B. Niewold et al.   ARTHRITIS AND RHEUMATISM

IRF-5 Is a Mediator of the Death Receptor-induced Apoptotic Signaling Pathway

(2008) Guodong Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Characterization of Murine Interferon Regulatory Factor 5 (IRF-5) and Its Role in the Innate Antiviral Response

(2008) Andrea Paun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Systemic Lupus Erythematosus

(2008) Anisur Rahman et al.   NEW ENGLAND JOURNAL OF MEDICINE

A cell-type-specific requirement for IFN regulatory factor 5 (IRF5) in Fas-induced apoptosis

(2008) A. Couzinet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA