Genetic deletion of the adaptor protein p66Shc increases susceptibility to short-term ischaemic myocardial injury via intracellular salvage pathways

Diazoxide postconditioning induces mitochondrial protein S-Nitrosylation and a redox-sensitive mitochondrial phosphorylation/translocation of RISK elements: no role for SAFE

(2013) C. Penna et al.   BASIC RESEARCH IN CARDIOLOGY

Deletion of the Activated Protein-1 Transcription Factor JunD Induces Oxidative Stress and Accelerates Age-Related Endothelial Dysfunction

(2013) Francesco Paneni et al.   CIRCULATION

Myocardial reperfusion injury: looking beyond primary PCI

(2013) Georg M. Fröhlich et al.   EUROPEAN HEART JOURNAL

CXC chemokine KC fails to induce neutrophil infiltration and neoangiogenesis in a mouse model of myocardial infarction

(2013) Hasan Oral et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Treatment with the CC chemokine-binding protein Evasin-4 improves post-infarction myocardial injury and survival in mice

(2013) Vincent Braunersreuther et al.   THROMBOSIS AND HAEMOSTASIS

Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice

(2013) Rafaela da Silva et al.   THROMBOSIS AND HAEMOSTASIS

Repetitive Myocardial Ischemia Promotes Coronary Growth in the Adult Mammalian Heart

(2013) Kory J. Lavine et al.   Journal of the American Heart Association

Inhibition of Nicotinamide Phosphoribosyltransferase Reduces Neutrophil-Mediated Injury in Myocardial Infarction

(2012) Fabrizio Montecucco et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of the Inflammatory Response in Cardiac Repair

(2012) Nikolaos G. Frangogiannis   CIRCULATION RESEARCH

Gene Silencing of the Mitochondrial Adaptor p66 Shc Suppresses Vascular Hyperglycemic Memory in Diabetes

(2012) Francesco Paneni et al.   CIRCULATION RESEARCH

Impact of ESC/ACCF/AHA/WHF universal definition of myocardial infarction on mortality at 10 years

(2012) F. M. Costa et al.   EUROPEAN HEART JOURNAL

Deletion of the ageing gene p66Shc reduces early stroke size following ischaemia/reperfusion brain injury

(2012) Remo D. Spescha et al.   EUROPEAN HEART JOURNAL

Treatment with Evasin-3 Reduces Atherosclerotic Vulnerability for Ischemic Stroke, but Not Brain Injury in Mice

(2012) Jean-Christophe Copin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cardioprotection: chances and challenges of its translation to the clinic

(2012) Gerd Heusch   LANCET

The p66Shcknockout mice are short lived under natural condition

(2011) Marco Giorgio et al.   AGING CELL

Cyclosporin variably and inconsistently reduces infarct size in experimental models of reperfused myocardial infarction: a systematic review and meta-analysis

(2011) WY Lim et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mitochondrial STAT3 Activation and Cardioprotection by Ischemic Postconditioning in Pigs With Regional Myocardial Ischemia/Reperfusion

(2011) Gerd Heusch et al.   CIRCULATION RESEARCH

When are pro-inflammatory cytokines SAFE in heart failure?

(2011) S. Lecour et al.   EUROPEAN HEART JOURNAL

CC chemokine CCL5 plays a central role impacting infarct size and post-infarction heart failure in mice

(2011) Fabrizio Montecucco et al.   EUROPEAN HEART JOURNAL

Repair After Myocardial Infarction, Between Fantasy and Reality

(2011) Elisa A. Liehn et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Lifespan-Regulator p66Shc in Mitochondria: Redox Enzyme or Redox Sensor?

(2010) Melanie Gertz et al.   ANTIOXIDANTS & REDOX SIGNALING

Single Administration of the CXC Chemokine-Binding Protein Evasin-3 During Ischemia Prevents Myocardial Reperfusion Injury in Mice

(2010) Fabrizio Montecucco et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion

(2010) Kerstin Boengler et al.   BASIC RESEARCH IN CARDIOLOGY

Mitochondrial kinase signalling pathways in myocardial protection from ischaemia/reperfusion-induced necrosis

(2010) T. Miura et al.   CARDIOVASCULAR RESEARCH

Greater resistance to inflammation at adulthood could contribute to extended life span of p66Shc−/− mice

(2010) Alessandra Berry et al.   EXPERIMENTAL GERONTOLOGY

STAT3 and cardiac remodeling

(2010) Arash Haghikia et al.   HEART FAILURE REVIEWS

Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66Shc and monoamine oxidase

(2009) Fabio Di Lisa et al.   BASIC RESEARCH IN CARDIOLOGY

The cardioprotective effects elicited by p66Shc ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury

(2009) Andrea Carpi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

CB2 cannabinoid receptor activation is cardioprotective in a mouse model of ischemia/reperfusion

(2009) Fabrizio Montecucco et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Oxidative stress and left ventricular remodelling after myocardial infarction

(2008) M. Hori et al.   CARDIOVASCULAR RESEARCH

Cardioprotection

(2008) Gerd Heusch et al.   CIRCULATION

The role of p66Shc deletion in age-associated arterial dysfunction and disease states

(2008) Giovanni G. Camici et al.   JOURNAL OF APPLIED PHYSIOLOGY

Roles of Endothelial Oxidases in Endothelium-derived Hyperpolarizing Factor Responses in Mice

(2008) Aya Takaki et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Final Common Molecular Pathways of Aging and Cardiovascular Disease

(2007) Francesco Cosentino et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Protective Role of CXC Receptor 4/CXC Ligand 12 Unveils the Importance of Neutrophils in Atherosclerosis

(2007) Alma Zernecke et al.   CIRCULATION RESEARCH