Mitochondrial injury and dysfunction in hypertension-induced cardiac damage

Musical chairs during mitophagy

(2014) Jörn Dengjel et al.   Autophagy

Mitochondrial protection restores renal function in swine atherosclerotic renovascular disease

(2014) Alfonso Eirin et al.   CARDIOVASCULAR RESEARCH

Mitochondrial damage-associated molecular patterns and vascular function

(2014) C. F. Wenceslau et al.   EUROPEAN HEART JOURNAL

Valsartan Regulates Myocardial Autophagy and Mitochondrial Turnover in Experimental Hypertension

(2014) Xin Zhang et al.   HYPERTENSION

Rationale and design of the EMBRACE STEMI Study: A phase 2a, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability and efficacy of intravenous Bendavia on reperfusion injury in patients treated with standard therapy including primary percutaneous coronary intervention and stenting for ST-segment elevation myocardial infarction

(2013) Anjan K. Chakrabarti et al.   AMERICAN HEART JOURNAL

Nox2-Induced Production of Mitochondrial Superoxide in Angiotensin II-Mediated Endothelial Oxidative Stress and Hypertension

(2013) Sergey I. Dikalov et al.   ANTIOXIDANTS & REDOX SIGNALING

After the banquet

(2013) Jianhui Zhu et al.   Autophagy

First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics

(2013) Hazel H Szeto   BRITISH JOURNAL OF PHARMACOLOGY

Compromised mitochondrial remodeling in compensatory hypertrophied myocardium of spontaneously hypertensive rat

(2013) Ying Tang et al.   CARDIOVASCULAR PATHOLOGY

Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

(2013) Sara Cogliati et al.   CELL

Anti-apoptotic and pro-survival effect of protocatechuic acid on hypertensive hearts

(2013) Jeng-Shyan Deng et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Mitochondria and Endothelial Function

(2013) Matthew A. Kluge et al.   CIRCULATION RESEARCH

Potential Role of BNIP3 in Cardiac Remodeling, Myocardial Stiffness, and Endoplasmic Reticulum

(2013) Antoine H. Chaanine et al.   Circulation-Heart Failure

Arginase I enhances atherosclerotic plaque stabilization by inhibiting inflammation and promoting smooth muscle cell proliferation

(2013) Xu-Ping Wang et al.   EUROPEAN HEART JOURNAL

Mitochondrial targeted peptides attenuate residual myocardial damage after reversal of experimental renovascular hypertension

(2013) Alfonso Eirin et al.   JOURNAL OF HYPERTENSION

Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ10, and angiotensin receptor blocker, losartan, on cardiovascular function

(2013) Jennifer McLachlan et al.   JOURNAL OF HYPERTENSION

Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology

(2013) Ming Zhan et al.   KIDNEY INTERNATIONAL

Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases

(2013) Stephen L. Archer   NEW ENGLAND JOURNAL OF MEDICINE

Peroxisome Proliferator-Activated Receptor δ Agonist, HPP593, Prevents Renal Necrosis under Chronic Ischemia

(2013) Larisa V. Fedorova et al.   PLoS One

Arginine de novo and nitric oxide production in disease states

(2012) Yvette C. Luiking et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

New Insights on Molecular Mechanisms of Renal Aging

(2012) R. Schmitt et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Adverse Alterations in Mitochondrial Function Contribute to Type 2 Diabetes Mellitus–Related Endothelial Dysfunction in Humans

(2012) Tinoy J. Kizhakekuttu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

L-arginine, tetrahydrobiopterin, nitric oxide and diabetes

(2012) Hai H. Hoang et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

A Mitochondrial Permeability Transition Pore Inhibitor Improves Renal Outcomes After Revascularization in Experimental Atherosclerotic Renal Artery Stenosis

(2012) Alfonso Eirin et al.   HYPERTENSION

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

(2012) Kenichi Shimada et al.   IMMUNITY

Mitochondrial dysfunction causing cardiac sodium channel downregulation in cardiomyopathy

(2012) Man Liu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

(2012) Takafumi Oka et al.   NATURE

Mitochondrial proteomic analysis reveals deficiencies in oxygen utilization in medullary thick ascending limb of Henle in the Dahl salt-sensitive rat

(2012) Nadezhda N. Zheleznova et al.   PHYSIOLOGICAL GENOMICS

Mitochondrial Fusion is Essential for Organelle Function and Cardiac Homeostasis

(2011) Yun Chen et al.   CIRCULATION RESEARCH

PGC-1β Deficiency Accelerates the Transition to Heart Failure in Pressure Overload Hypertrophy

(2011) Christian Riehle et al.   CIRCULATION RESEARCH

Making heads or tails of phospholipids in mitochondria

(2011) Christof Osman et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial Targeted Antioxidant Peptide Ameliorates Hypertensive Cardiomyopathy

(2011) Dao-Fu Dai et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Mitochondrial Biogenesis in Kidney Disease

(2011) J. M. Weinberg   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis

(2011) Andrew Oberst et al.   NATURE

Resveratrol Improves Survival, Hemodynamics and Energetics in a Rat Model of Hypertension Leading to Heart Failure

(2011) Stéphanie Rimbaud et al.   PLoS One

Identification and characterization of a functional mitochondrial angiotensin system

(2011) P. M. Abadir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animal and human studies with the mitochondria-targeted antioxidant MitoQ

(2010) Robin A.J. Smith et al.   Annals of the New York Academy of Sciences

Losartan improved respiratory function and coenzyme Q content in brain mitochondria of young spontaneously hypertensive rats

(2010) Z. Sumbalová et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

TNF-α induces mitochondrial dysfunction in 3T3-L1 adipocytes

(2010) Xiao-Hui Chen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Impaired ATP turnover and ADP supply depress cardiac mitochondrial respiration and elevate superoxide in nonfailing spontaneously hypertensive rat hearts

(2009) Anthony J. R. Hickey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cardiovascular Inflammation and Lesion Cell Apoptosis

(2009) Zhaoqing Yang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cardiac mitochondrial function and tissue remodelling are improved by a non-antihypertensive dose of enalapril in spontaneously hypertensive rats

(2009) Barbara Piotrkowski et al.   FREE RADICAL RESEARCH

Mitochondria-Targeted Antioxidant MitoQ 10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy

(2009) Delyth Graham et al.   HYPERTENSION

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial Dysfunction in the Hypertensive Rat Brain

(2008) Ana Lopez-Campistrous et al.   HYPERTENSION

Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction

(2008) Christophe Piot et al.   NEW ENGLAND JOURNAL OF MEDICINE

Molecular Mechanisms of Angiotensin II–Mediated Mitochondrial Dysfunction

(2007) Abdulrahman K. Doughan et al.   CIRCULATION RESEARCH

The PPARα-PGC-1αAxis Controls Cardiac Energy Metabolism in Healthy and Diseased Myocardium

(2007) Jennifer G. Duncan et al.   PPAR Research