New Insights on Molecular Mechanisms of Renal Aging

Donor Age-Specific Injury and Immune Responses

(2011) R. Oberhuber et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Infiltrating cellular pattern in kidney graft biopsies translates into forkhead box protein 3 up-regulation and p16INK4α senescence protein down-regulation in patients treated with belatacept compared to cyclosporin A

(2011) J. Furuzawa-Carballeda et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Aging and the kidney

(2011) Norberto Perico et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Telomeres and Telomerase in Renal Health

(2011) L. P. Wills et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Ageing theories unified

(2011) Daniel P. Kelly   NATURE

Telomere dysfunction induces metabolic and mitochondrial compromise

(2011) Ergün Sahin et al.   NATURE

Bardoxolone Methyl and Kidney Function in CKD with Type 2 Diabetes

(2011) Pablo E. Pergola et al.   NEW ENGLAND JOURNAL OF MEDICINE

Is cellular senescence important in pediatric kidney disease?

(2011) Christoph Jacobi et al.   PEDIATRIC NEPHROLOGY

Repair of injured proximal tubule does not involve specialized progenitors

(2011) B. D. Humphreys et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and characterization of a functional mitochondrial angiotensin system

(2011) P. M. Abadir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intravital Two-Photon Microscopy Assessment of Renal Protection Efficacy of siRNA for p53 in Experimental Rat Kidney Transplantation Models

(2010) Ryoichi Imamura et al.   CELL TRANSPLANTATION

Sirt1 activation protects the mouse renal medulla from oxidative injury

(2010) Wenjuan He et al.   JOURNAL OF CLINICAL INVESTIGATION

Senescent mesenchymal cells accumulate in human fibrosis by a telomere-independent mechanism and ameliorate fibrosis through matrix metalloproteinases

(2010) Gayani Nadika Pitiyage et al.   JOURNAL OF PATHOLOGY

Cell Senescence in the Aging Kidney

(2010) H. Yang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

2009 Nobel Prize in Physiology or Medicine: telomeres and telomerase

(2010) E Varela et al.   ONCOGENE

Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer

(2010) Daniel Herranz et al.   Nature Communications

Disruption of the Ang II type 1 receptor promotes longevity in mice

(2009) Ariela Benigni et al.   JOURNAL OF CLINICAL INVESTIGATION

PPAR control: it's SIRTainly as easy as PGC

(2009) Mary C Sugden et al.   JOURNAL OF ENDOCRINOLOGY

Telomere Shortening Reduces Regenerative Capacity after Acute Kidney Injury

(2009) J. H. Westhoff et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

siRNA Targeted to p53 Attenuates Ischemic and Cisplatin-Induced Acute Kidney Injury

(2009) B. A. Molitoris et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The PPAR  Agonist Pioglitazone Ameliorates Aging-Related Progressive Renal Injury

(2009) H.-C. Yang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Donor Age and Renal P-Glycoprotein Expression Associate with Chronic Histological Damage in Renal Allografts

(2009) M. Naesens et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Prediction, Progression, and Outcomes of Chronic Kidney Disease in Older Adults

(2009) S. Anderson et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Angiotensin receptors as determinants of life span

(2009) Paola Cassis et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

An old virtue to improve senior programs

(2009) Johan W. de Fijter   TRANSPLANT INTERNATIONAL

Markers of cellular senescence in zero hour biopsies predict outcome in renal transplantation

(2008) Christian Koppelstaetter et al.   AGING CELL

Cellular senescence in pretransplant renal biopsies predicts postoperative organ function

(2008) Liane M. McGlynn et al.   AGING CELL

Sustained Tubulo-interstitial Protection in SHRs by Transient Losartan Treatment: An Effect of Decelerated Aging?

(2008) M. Baumann et al.   AMERICAN JOURNAL OF HYPERTENSION

Recovery of Kidney Function After Acute Kidney Injury in the Elderly: A Systematic Review and Meta-analysis

(2008) Roland Schmitt et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Effects of Donor Age and Cell Senescence on Kidney Allograft Survival

(2008) A. Melk et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Senescence of Activated Stellate Cells Limits Liver Fibrosis

(2008) Valery Krizhanovsky et al.   CELL

Kidney in Hypertension

(2008) Thomas M. Coffman et al.   HYPERTENSION

Hypertension Induces Somatic Cellular Senescence in Rats and Humans by Induction of Cell Cycle Inhibitor p16 INK4a

(2008) Jens H. Westhoff et al.   HYPERTENSION

Zag Expression during Aging Suppresses Proliferation after Kidney Injury

(2008) R. Schmitt et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Acute Kidney Injury Increases Risk of ESRD among Elderly

(2008) A. Ishani et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The aging kidney

(2008) Xin J. Zhou et al.   KIDNEY INTERNATIONAL

Patient and Graft Outcomes from Deceased Kidney Donors Age 70 Years and Older: An Analysis of the Organ Procurement Transplant Network/United Network of Organ Sharing Database

(2008) Disaya Chavalitdhamrong et al.   TRANSPLANTATION

Angiotensin II–Mediated Oxidative DNA Damage Accelerates Cellular Senescence in Cultured Human Vascular Smooth Muscle Cells via Telomere-Dependent and Independent Pathways

(2007) Karl E. Herbert et al.   CIRCULATION RESEARCH