The methylation hypothesis of pharmacoresistance in epilepsy

Defining Clinico-Neuropathological Subtypes of Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis

(2012) Ingmar Blümcke et al.   BRAIN PATHOLOGY

Molecular Pathways: Regulation and Therapeutic Implications of Multidrug Resistance

(2012) K. G. Chen et al.   CLINICAL CANCER RESEARCH

The emerging role of DNA methylation in epileptogenesis

(2012) Katja Kobow et al.   EPILEPSIA

Finding a better drug for epilepsy: Antiepileptogenesis targets

(2012) Katja Kobow et al.   EPILEPSIA

Differential DNA Methylation Patterns Define Status Epilepticus and Epileptic Tolerance

(2012) S. F. C. Miller-Delaney et al.   JOURNAL OF NEUROSCIENCE

Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects

(2012) Eva M Jimenez-Mateos et al.   NATURE MEDICINE

Cerebral expression of drug transporters in epilepsy

(2011) Eleonora Aronica et al.   ADVANCED DRUG DELIVERY REVIEWS

Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy

(2011) Shawn McClelland et al.   ANNALS OF NEUROLOGY

Molecular biomarkers of epileptogenesis

(2011) Asla Pitkänen et al.   Biomarkers in Medicine

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

The methylation hypothesis: Do epigenetic chromatin modifications play a role in epileptogenesis?

(2011) Katja Kobow et al.   EPILEPSIA

Modern antiepileptic drug development has failed to deliver: Ways out of the current dilemma

(2011) Wolfgang Löscher et al.   EPILEPSIA

Epigenetic regulation on GABRB2 isoforms expression: Developmental variations and disruptions in psychotic disorders

(2011) Cunyou Zhao et al.   SCHIZOPHRENIA RESEARCH

Expression pattern of miR-146a, an inflammation-associated microRNA, in experimental and human temporal lobe epilepsy

(2010) E. Aronica et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy

(2010) Markus Riessland et al.   HUMAN MOLECULAR GENETICS

Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice

(2010) S. Peleg et al.   SCIENCE

RNA regulation of epigenetic processes

(2009) John S. Mattick et al.   BIOESSAYS

Hijacking the Chromatin Remodeling Machinery: Impact of SWI/SNF Perturbations in Cancer

(2009) B. Weissman et al.   CANCER RESEARCH

Epigenetic Therapy: Histone Acetylation, DNA Methylation and Anti-Cancer Drug Discovery

(2009) A. Ganesan et al.   CURRENT CANCER DRUG TARGETS

MicroRNAs: Predictors and modifiers of chemo- and radiotherapy in different tumour types

(2009) Richard Hummel et al.   EUROPEAN JOURNAL OF CANCER

Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment

(2009) Cristina Rodriguez-Antona et al.   HUMAN GENETICS

LBH589 induces up to 10-fold SMN protein levels by several independent mechanisms and is effective even in cells from SMA patients non-responsive to valproate

(2009) Lutz Garbes et al.   HUMAN MOLECULAR GENETICS

Increased Reelin Promoter Methylation Is Associated With Granule Cell Dispersion in Human Temporal Lobe Epilepsy

(2009) Katja Kobow et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Long non-coding RNAs: insights into functions

(2009) Tim R. Mercer et al.   NATURE REVIEWS GENETICS

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SWI/SNF Associates with Nascent Pre-mRNPs and Regulates Alternative Pre-mRNA Processing

(2009) Anu Tyagi et al.   PLoS Genetics

A set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortex

(2008) Nikolaos Mellios et al.   HUMAN MOLECULAR GENETICS

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

Specific expression of long noncoding RNAs in the mouse brain

(2008) T. R. Mercer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-373 induces expression of genes with complementary promoter sequences

(2008) R. F. Place et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrinsic Severity as a Determinant of Antiepileptic Drug Refractoriness

(2008) Michael A. Rogawski et al.   Epilepsy Currents