Blood-brain barrier dysfunction-induced inflammatory signaling in brain pathology and epileptogenesis

Macrophages prevent hemorrhagic infarct transformation in murine stroke models

(2012) Michael Gliem et al.   ANNALS OF NEUROLOGY

Seizure-induced brain-borne inflammation sustains seizure recurrence and blood-brain barrier damage

(2012) Laura Librizzi et al.   ANNALS OF NEUROLOGY

Hippocampal microRNA-132 mediates stress-inducible cognitive deficits through its acetylcholinesterase target

(2012) G. Shaltiel et al.   Brain Structure & Function

Inflammatory events at blood-brain barrier in neuroinflammatory and neurodegenerative disorders: Implications for clinical disease

(2012) Helga E. de Vries et al.   EPILEPSIA

Cliniconeuropathologic correlations show astroglial albumin storage as a common factor in epileptogenic vascular lesions

(2012) Anna Raabe et al.   EPILEPSIA

The evolutionary significance of depression in Pathogen Host Defense (PATHOS-D)

(2012) C L Raison et al.   MOLECULAR PSYCHIATRY

The role of inflammation in epileptogenesis

(2012) Annamaria Vezzani et al.   NEUROPHARMACOLOGY

Brain inflammation as a biomarker in epilepsy

(2011) Annamaria Vezzani et al.   Biomarkers in Medicine

Activation of toll-like receptor, RAGE and HMGB1 signalling in malformations of cortical development

(2011) E. Zurolo et al.   BRAIN

IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures

(2011) Annamaria Vezzani et al.   BRAIN BEHAVIOR AND IMMUNITY

Atorvastatin treatment during epileptogenesis in a rat model for temporal lobe epilepsy

(2011) Erwin A. van Vliet et al.   EPILEPSIA

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Adaptive Alternative Splicing Correlates with Less Environmental Risk of Parkinsonism

(2011) Liat BenMoyal-Segal et al.   Neurodegenerative Diseases

Interleukin-1β Biosynthesis Inhibition Reduces Acute Seizures and Drug Resistant Chronic Epileptic Activity in Mice

(2011) Mattia Maroso et al.   Neurotherapeutics

Efficacy of Anti-Inflammatory Therapy in a Model of Acute Seizures and in a Population of Pediatric Drug Resistant Epileptics

(2011) Nicola Marchi et al.   PLoS One

Anti-inflammatory effects of the anticonvulsant drug levetiracetam on electrophysiological properties of astroglia are mediated via TGFβ1 regulation

(2010) Martin N Stienen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inflammation induced by LPS enhances epileptogenesis in immature rat and may be partially reversed by IL1RA

(2010) Stéphane Auvin et al.   EPILEPSIA

TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke

(2010) Kristian P Doyle et al.   Journal of Neuroinflammation

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

(2010) Mattia Maroso et al.   NATURE MEDICINE

Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury

(2010) Dan Shlosberg et al.   Nature Reviews Neurology

The role of inflammation in epilepsy

(2010) Annamaria Vezzani et al.   Nature Reviews Neurology

Valproic acid induces microglial dysfunction, not apoptosis, in human glial cultures

(2010) Hannah M. Gibbons et al.   NEUROBIOLOGY OF DISEASE

The Science of Stroke: Mechanisms in Search of Treatments

(2010) Michael A. Moskowitz et al.   NEURON

Inhibitory role for GABA in autoimmune inflammation

(2010) R. Bhat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood–brain barrier breakdown-inducing astrocytic transformation: Novel targets for the prevention of epilepsy

(2009) Alon Friedman et al.   EPILEPSY RESEARCH

Transcriptome Profiling Reveals TGF-  Signaling Involvement in Epileptogenesis

(2009) L. P. Cacheaux et al.   JOURNAL OF NEUROSCIENCE

Astrocytic Dysfunction in Epileptogenesis: Consequence of Altered Potassium and Glutamate Homeostasis?

(2009) Y. David et al.   JOURNAL OF NEUROSCIENCE

Antagonism of peripheral inflammation reduces the severity of status epilepticus

(2008) Nicola Marchi et al.   NEUROBIOLOGY OF DISEASE

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Inflammation as a causative factor in the aetiology of Parkinson's disease

(2007) P S Whitton   BRITISH JOURNAL OF PHARMACOLOGY

Innate and adaptive immunity during epileptogenesis and spontaneous seizures: Evidence from experimental models and human temporal lobe epilepsy

(2007) Teresa Ravizza et al.   NEUROBIOLOGY OF DISEASE

The role of inflammation in CNS injury and disease

(2006) Sian-Marie Lucas et al.   BRITISH JOURNAL OF PHARMACOLOGY