Assembling pieces of the centromere epigenetics puzzle

Chromosomal Instability Confers Intrinsic Multidrug Resistance

(2011) A. J. X. Lee et al.   CANCER RESEARCH

Induced Ectopic Kinetochore Assembly Bypasses the Requirement for CENP-A Nucleosomes

(2011) Karen E. Gascoigne et al.   CELL

Mobilization and recruitment of HP1β: A bimodal response to DNA breakage

(2011) Nabieh Ayoub et al.   CELL CYCLE

Histone H3K4 methylation keeps centromeres open for business

(2011) Kaitlin M Stimpson et al.   EMBO JOURNAL

Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

(2011) Juan Sandoval et al.   Epigenetics

Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP

(2011) H. Hu et al.   GENES & DEVELOPMENT

Identification of Noncoding Transcripts from within CENP-A Chromatin at Fission Yeast Centromeres

(2011) Eun Shik Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of HP1α regulation in human breast cancer cells

(2011) Rune Thomsen et al.   MOLECULAR CARCINOGENESIS

Crystal structure of the human centromeric nucleosome containing CENP-A

(2011) Hiroaki Tachiwana et al.   NATURE

Increased methylation variation in epigenetic domains across cancer types

(2011) Kasper Daniel Hansen et al.   NATURE GENETICS

Heterochromatin establishment in the context of genome-wide epigenetic reprogramming

(2011) Aline V. Probst et al.   TRENDS IN GENETICS

Premitotic Assembly of Human CENPs -T and -W Switches Centromeric Chromatin to a Mitotic State

(2011) Lisa Prendergast et al.   PLOS BIOLOGY

The Polycomb Group Protein Bmi-1 Is Essential for the Growth of Multiple Myeloma Cells

(2010) Z. Jagani et al.   CANCER RESEARCH

The fate of metaphase kinetochores is weighed in the balance of SUMOylation during S phase

(2010) Debaditya Mukhopadhyay et al.   CELL CYCLE

Contrasting models for kinetochore microtubule attachment in mammalian cells

(2010) Bruce F. McEwen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Centromere inactivation and epigenetic modifications of a plant chromosome with three functional centromeres

(2010) Wenli Zhang et al.   CHROMOSOMA

Kinetochore assembly: if you build it, they will come

(2010) Karen E Gascoigne et al.   CURRENT OPINION IN CELL BIOLOGY

A Strand-Specific Burst in Transcription of Pericentric Satellites Is Required for Chromocenter Formation and Early Mouse Development

(2010) Aline.V. Probst et al.   DEVELOPMENTAL CELL

Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore

(2010) Jan H Bergmann et al.   EMBO JOURNAL

Centromeres: The wild west of the post-genomic age

(2010) Samantha G. Zeitlin   Epigenetics

The MIS12 complex is a protein interaction hub for outer kinetochore assembly

(2010) Arsen Petrovic et al.   JOURNAL OF CELL BIOLOGY

Dual recognition of CENP-A nucleosomes is required for centromere assembly

(2010) Christopher W. Carroll et al.   JOURNAL OF CELL BIOLOGY

Inner centromere formation requires hMis14, a trident kinetochore protein that specifically recruits HP1 to human chromosomes

(2010) Tomomi Kiyomitsu et al.   JOURNAL OF CELL BIOLOGY

The structure of (CENP-A–H4)2 reveals physical features that mark centromeres

(2010) Nikolina Sekulic et al.   NATURE

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

(2010) Sihem Cheloufi et al.   NATURE

Epigenetic modifications and human disease

(2010) Anna Portela et al.   NATURE BIOTECHNOLOGY

Epigenetic regulation of the human p53 gene promoter by the CTCF transcription factor in transformed cell lines

(2010) E Soto-Reyes et al.   ONCOGENE

Variability in the Incidence of miRNAs and Genes in Fragile Sites and the Role of Repeats and CpG Islands in the Distribution of Genetic Material

(2010) Alessandro Laganà et al.   PLoS One

HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeres

(2010) M. Shuaib et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A super-resolution map of the vertebrate kinetochore

(2010) S. A. Ribeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity

(2010) D. Cifuentes et al.   SCIENCE

Continuous Requirement for the Clr4 Complex But Not RNAi for Centromeric Heterochromatin Assembly in Fission Yeast Harboring a Disrupted RITS Complex

(2010) Sreenath Shanker et al.   PLoS Genetics

Efficient yeast ChIP-Seq using multiplex short-read DNA sequencing

(2009) Philippe Lefrançois et al.   BMC GENOMICS

Genome-wide DNA methylation profiles in precancerous conditions and cancers

(2009) Yae Kanai   CANCER SCIENCE

Enhanced genomic instabilities caused by deregulated microtubule dynamics and chromosome segregation: a perspective from genetic studies in mice

(2009) C. V. Rao et al.   CARCINOGENESIS

Protein Architecture of the Human Kinetochore Microtubule Attachment Site

(2009) Xiaohu Wan et al.   CELL

Hierarchical Inactivation of a Synthetic Human Kinetochore by a Chromatin Modifier

(2009) Stefano Cardinale et al.   MOLECULAR BIOLOGY OF THE CELL

CENP-H–containing Complex Facilitates Centromere Deposition of CENP-A in Cooperation with FACT and CHD1

(2009) Masahiro Okada et al.   MOLECULAR BIOLOGY OF THE CELL

CENPA overexpression promotes genome instability in pRb-depleted human cells

(2009) Angela Amato et al.   Molecular Cancer

Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

(2009) Akiko Doi et al.   NATURE GENETICS

H3.3/H2A.Z double variant–containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions

(2009) Chunyuan Jin et al.   NATURE GENETICS

Small silencing RNAs: an expanding universe

(2009) Megha Ghildiyal et al.   NATURE REVIEWS GENETICS

Neocentromeres Form Efficiently at Multiple Possible Loci in Candida albicans

(2009) Carrie Ketel et al.   PLoS Genetics

CCAN Makes Multiple Contacts with Centromeric DNA to Provide Distinct Pathways to the Outer Kinetochore

(2008) Tetsuya Hori et al.   CELL

A new class of retroviral and satellite encoded small RNAs emanates from mammalian centromeres

(2008) Dawn M. Carone et al.   CHROMOSOMA

Histone modifications associated with both A and B chromosomes of maize

(2008) Weiwei Jin et al.   CHROMOSOME RESEARCH

Colon Cancer: It's CIN or CIMP

(2008) J.-P. Issa   CLINICAL CANCER RESEARCH

Inactivation of a Human Kinetochore by Specific Targeting of Chromatin Modifiers

(2008) Megumi Nakano et al.   DEVELOPMENTAL CELL

Roles of the EZH2 histone methyltransferase in cancer epigenetics

(2008) Jeffrey A. Simon et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Epigenetic drivers and genetic passengers on the road to cancer

(2008) Carla Sawan et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Perturbation of HP1 localization and chromatin binding ability causes defects in sister-chromatid cohesion

(2008) Akira Inoue et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Cell cycle control of centromeric repeat transcription and heterochromatin assembly

(2008) Ee Sin Chen et al.   NATURE

Heterochromatin and RNAi Are Required to Establish CENP-A Chromatin at Centromeres

(2008) H. D. Folco et al.   SCIENCE

Role of non-coding RNA and heterochromatin in aneuploidy and cancer

(2008) Željka Pezer et al.   SEMINARS IN CANCER BIOLOGY

KNL1 and the CENP-H/I/K Complex Coordinately Direct Kinetochore Assembly in Vertebrates

(2007) Iain M. Cheeseman et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular architecture of the kinetochore–microtubule interface

(2007) Iain M. Cheeseman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY