A novel sulfonyl chromen-4-ones (CHW09) preferentially kills oral cancer cells showing apoptosis, oxidative stress, and DNA damage

Recent Development of Sulfonyl or Sulfonamide Hybrids as Potential Anticancer Agents: A Key Review

(2018) K. P. Rakesh et al.   Anti-Cancer Agents in Medicinal Chemistry

Berberine impairs embryonic development in vitro and in vivo through oxidative stress-mediated apoptotic processes

(2017) Chien-Hsun Huang et al.   ENVIRONMENTAL TOXICOLOGY

4β-Hydroxywithanolide E selectively induces oxidative DNA damage for selective killing of oral cancer cells

(2017) Jen-Yang Tang et al.   ENVIRONMENTAL TOXICOLOGY

An Overview of 2-Styrylchromones: Natural Occurrence, Synthesis, Reactivity and Biological Properties

(2017) Clementina M. M. Santos et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

MitoTEMPO Prevents Oxalate Induced Injury in NRK-52E Cells via Inhibiting Mitochondrial Dysfunction and Modulating Oxidative Stress

(2017) Jiaqiao Zhang et al.   Oxidative Medicine and Cellular Longevity

Reactive oxygen species mediate soft corals-derived sinuleptolide-induced antiproliferation and DNA damage in oral cancer cells

(2017) Yung-Ting Chang et al.   OncoTargets and Therapy

Withaferin A Induces Oxidative Stress-Mediated Apoptosis and DNA Damage in Oral Cancer Cells

(2017) Hsueh-Wei Chang et al.   Frontiers in Physiology

Development of 1-Amino-4-(phenylamino)anthraquinone-2-sulfonate Sodium Derivatives as a New Class of Inhibitors of RANKL-Induced Osteoclastogenesis

(2016) Chia-Chung Lee et al.   ARCHIV DER PHARMAZIE

Sinuleptolide inhibits proliferation of oral cancer Ca9-22 cells involving apoptosis, oxidative stress, and DNA damage

(2016) Yung-Ting Chang et al.   ARCHIVES OF ORAL BIOLOGY

Novel chromone and xanthone derivatives: Synthesis and ROS/RNS scavenging activities

(2016) Carina Proença et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

One-Pot Synthesis of Benzopyran-4-ones with Cancer Preventive and Therapeutic Potential

(2016) Oualid Talhi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases

(2016) Pierpaola Davalli et al.   Oxidative Medicine and Cellular Longevity

Tenuifolide B from Cinnamomum tenuifolium Stem Selectively Inhibits Proliferation of Oral Cancer Cells via Apoptosis, ROS Generation, Mitochondrial Depolarization, and DNA Damage

(2016) Chung-Yi Chen et al.   Toxins

Reactive oxygen species mediate Terbufos-induced apoptosis in mouse testicular cell lines via the modulation of cell cycle and pro-apoptotic proteins

(2015) Jui-Hsiang Hung et al.   ENVIRONMENTAL TOXICOLOGY

Chromone: A Valid Scaffold in Medicinal Chemistry

(2014) Alexandra Gaspar et al.   CHEMICAL REVIEWS

Potential Use of Dietary Natural Products, Especially Polyphenols, for Improving Type-1 Allergic Symptoms

(2014) Yoshio Kumazawa et al.   CURRENT PHARMACEUTICAL DESIGN

Chromones as a privileged scaffold in drug discovery: A review

(2014) Rangappa S. Keri et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Studies on the antioxidant activities of some new chromone compounds

(2014) Aleksandra Kładna et al.   LUMINESCENCE

Cracking the Cytotoxicity Code: Apoptotic Induction of 10-Acetylirciformonin B is Mediated through ROS Generation and Mitochondrial Dysfunction

(2014) Huei-Chuan Shih et al.   Marine Drugs

Depolarization Controls TRAIL-Sensitization and Tumor-Selective Killing of Cancer Cells: Crosstalk with ROS

(2014) Yoshihiro Suzuki-Karasaki et al.   Frontiers in Oncology

Golden Berry-Derived 4β-hydroxywithanolide E for Selectively Killing Oral Cancer Cells by Generating ROS, DNA Damage, and Apoptotic Pathways

(2013) Chien-Chih Chiu et al.   PLoS One

Flow Cytometric Quantification of All Phases of the Cell Cycle and Apoptosis in a Two-Color Fluorescence Plot

(2013) Christine Vignon et al.   PLoS One

Anticancer Drug Design Using Scaffolds of β-Lactams, Sulfonamides, Quinoline, Quinoxaline and Natural Products. Drugs Advances in Clinical Trials

(2012) I. Balderas-Renteria et al.   CURRENT MEDICINAL CHEMISTRY

Advances in C-glycosylflavonoid Research

(2012) Oualid Oualid et al.   CURRENT ORGANIC CHEMISTRY

Antiproliferative effects of goniothalamin on Ca9-22 oral cancer cells through apoptosis, DNA damage and ROS induction

(2012) Ching-Yu Yen et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Recyclizations of 3-formylchromones with binucleophiles

(2012) Andrey S. Plaskon et al.   TETRAHEDRON

Antitumor agents 292. Design, synthesis and pharmacological study of S- and O-substituted 7-mercapto- or hydroxy-coumarins and chromones as potent cytotoxic agents

(2011) Ying Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Goniothalamin Inhibits Growth of Human Lung Cancer Cells through DNA Damage, Apoptosis, and Reduced Migration Ability

(2011) Chien-Chih Chiu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Substituted Chromones as Highly Potent Nontoxic Inhibitors, Specific for the Breast Cancer Resistance Protein

(2011) Glaucio Valdameri et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and anticancer activity of chromone-based analogs of lavendustin A

(2010) Dong Hyuk Nam et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthetic strategies in the construction of chromones

(2010) Nian-Guang Li et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Exogenous Antioxidants—Double-Edged Swords in Cellular Redox State: Health Beneficial Effects at Physiologic Doses versus Deleterious Effects at High Doses

(2010) Jaouad Bouayed et al.   Oxidative Medicine and Cellular Longevity

Anti-inflammatory potential of 2-styrylchromones regarding their interference with arachidonic acid metabolic pathways

(2009) Ana Gomes et al.   BIOCHEMICAL PHARMACOLOGY

Synthesis and antioxidant properties of new chromone derivatives

(2009) Ana Gomes et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of 2-styrylchromones as a novel class of antiproliferative agents targeting carcinoma cells

(2009) Arthur Y. Shaw et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

4′-Methoxy-2-styrylchromone a novel microtubule-stabilizing antimitotic agent

(2007) Joana Marinho et al.   BIOCHEMICAL PHARMACOLOGY

Flavonoids as RTK inhibitors and potential anticancer agents

(2007) Florence Teillet et al.   MEDICINAL RESEARCH REVIEWS