Resveratrol and cancer: focus on in vivo evidence

Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer

(2016) Randall F Holcombe et al.   Cancer Management and Research

Resveratrol-based combinatorial strategies for cancer management

(2013) Chandra K. Singh et al.   Annals of the New York Academy of Sciences

Dietary grape polyphenol resveratrol increases mammary tumor growth and metastasis in immunocompromised mice

(2013) Linette Castillo-Pichardo et al.   BMC Complementary and Alternative Medicine

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Resveratrol and Clinical Trials: The Crossroad from In Vitro Studies to Human Evidence

(2013) Joao Tomé-Carneiro et al.   CURRENT PHARMACEUTICAL DESIGN

Trimethoxy-Resveratrol and Piceatannol Administered Orally Suppress and Inhibit Tumor Formation and Growth in Prostate Cancer Xenografts

(2013) Steven J. Dias et al.   PROSTATE

One-Year Consumption of a Grape Nutraceutical Containing Resveratrol Improves the Inflammatory and Fibrinolytic Status of Patients in Primary Prevention of Cardiovascular Disease

(2012) João Tomé-Carneiro et al.   AMERICAN JOURNAL OF CARDIOLOGY

A phase 2 study of SRT501 (resveratrol) with bortezomib for patients with relapsed and or refractory multiple myeloma

(2012) Rakesh Popat et al.   BRITISH JOURNAL OF HAEMATOLOGY

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Resveratrol Helps Recovery from Fatty Liver and Protects against Hepatocellular Carcinoma Induced by Hepatitis B Virus X Protein in a Mouse Model

(2012) H.-C. Lin et al.   Cancer Prevention Research

Resveratrol Supplementation Does Not Improve Metabolic Function in Nonobese Women with Normal Glucose Tolerance

(2012) Jun Yoshino et al.   Cell Metabolism

High-Dose Resveratrol Supplementation in Obese Men: An Investigator-Initiated, Randomized, Placebo-Controlled Clinical Trial of Substrate Metabolism, Insulin Sensitivity, and Body Composition

(2012) M. M. Poulsen et al.   DIABETES

Pilot Study of Resveratrol in Older Adults With Impaired Glucose Tolerance

(2012) Jill P. Crandall et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus

(2012) Jayesh Kumar Bhatt et al.   NUTRITION RESEARCH

Resveratrol and cellular mechanisms of cancer prevention

(2011) Yogeshwer Shukla et al.   Annals of the New York Academy of Sciences

Chemopreventive effects of resveratrol and resveratrol derivatives

(2011) Thomas Szekeres et al.   Annals of the New York Academy of Sciences

Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients

(2011) Pál Brasnyó et al.   BRITISH JOURNAL OF NUTRITION

Breast cancer statistics, 2011

(2011) Carol DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Breast Cancer Incidence Rates in U.S. Women Are No Longer Declining

(2011) C. DeSantis et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Phase I Randomized, Double-Blind Pilot Study of Micronized Resveratrol (SRT501) in Patients with Hepatic Metastases--Safety, Pharmacokinetics, and Pharmacodynamics

(2011) L. M. Howells et al.   Cancer Prevention Research

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

(2011) Silvie Timmers et al.   Cell Metabolism

Role of 5-lipoxygenase in resveratrol mediated suppression of 7,12-dimethylbenz(α)anthracene-induced mammary carcinogenesis in rats

(2011) Mary Chatterjee et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Resveratrol prevents inflammation-dependent hepatic melanoma metastasis by inhibiting the secretion and effects of interleukin-18

(2011) Clarisa Salado et al.   Journal of Translational Medicine

Resveratrol improves insulin signaling in a tissue-specific manner under insulin-resistant conditions only: in vitro and in vivo experiments in rodents

(2011) Wonyoung Kang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Enhancing the bioavailability of resveratrol by combining it with piperine

(2011) Jeremy J. Johnson et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Resveratrol Inhibits Pancreatic Cancer Stem Cell Characteristics in Human and KrasG12D Transgenic Mice by Inhibiting Pluripotency Maintaining Factors and Epithelial-Mesenchymal Transition

(2011) Sharmila Shankar et al.   PLoS One

Resveratrol Inhibits Growth of Orthotopic Pancreatic Tumors through Activation of FOXO Transcription Factors

(2011) Sanjit K. Roy et al.   PLoS One

Resveratrol modulates adipokine expression and improves insulin sensitivity in adipocytes: Relative to inhibition of inflammatory responses

(2010) Liu Kang et al.   BIOCHIMIE

Resveratrol Suppresses Oxidative Stress and Inflammatory Response in Diethylnitrosamine-Initiated Rat Hepatocarcinogenesis

(2010) A. Bishayee et al.   Cancer Prevention Research

Resveratrol Modulates Drug- and Carcinogen-Metabolizing Enzymes in a Healthy Volunteer Study

(2010) H.-H. S. Chow et al.   Cancer Prevention Research

Resveratrol, a Red Wine Polyphenol, Suppresses Pancreatic Cancer by Inhibiting Leukotriene A4 Hydrolase

(2010) N. Oi et al.   CANCER RESEARCH

Repeat Dose Study of the Cancer Chemopreventive Agent Resveratrol in Healthy Volunteers: Safety, Pharmacokinetics, and Effect on the Insulin-like Growth Factor Axis

(2010) V. A. Brown et al.   CANCER RESEARCH

Clinical Pharmacology of Resveratrol and Its Metabolites in Colorectal Cancer Patients

(2010) K. R. Patel et al.   CANCER RESEARCH

trans-Resveratrol Reduces Precancerous Colonic Lesions in Dimethylhydrazine-Treated Rats

(2010) Irene Alfaras et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Suppression of the Inflammatory Cascade is Implicated in Resveratrol Chemoprevention of Experimental Hepatocarcinogenesis

(2010) Anupam Bishayee et al.   PHARMACEUTICAL RESEARCH

Resveratrol enhances ultraviolet B-induced cell death through nuclear factor-κB pathway in human epidermoid carcinoma A431 cells

(2009) Preeti Roy et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Central Administration of Resveratrol Improves Diet-Induced Diabetes

(2009) Giorgio Ramadori et al.   ENDOCRINOLOGY

Resveratrol treatment protects against doxorubicin-induced cardiotoxicity by alleviating oxidative damage

(2009) Elif Tatlidede et al.   FREE RADICAL RESEARCH

Chemopreventive doses of resveratrol do not produce cardiotoxicity in a rodent model of hepatocellular carcinoma

(2009) Daniel J. Luther et al.   INVESTIGATIONAL NEW DRUGS

Influence of dietary resveratrol on early and late molecular markers of 1,2-dimethylhydrazine–induced colon carcinogenesis

(2009) Murugan Sengottuvelan et al.   NUTRITION

Natural Products for Chemopreventive and Adjunctive Therapy in Oncologic Disease

(2009) Tiffany Dennis et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Curcumin Synergizes With Resveratrol to Inhibit Colon Cancer

(2009) Adhip P. N. Majumdar et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Regulation of cell survival by resveratrol involves inhibition of NFκB-regulated gene expression in prostate cancer cells

(2009) Dixan A. Benitez et al.   PROSTATE

Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1β-induced NF-κB-mediated inflammation and apoptosis

(2009) Constanze Csaki et al.   ARTHRITIS RESEARCH & THERAPY

Cancer chemopreventive and therapeutic potential of resveratrol: Mechanistic perspectives

(2008) Joydeb Kumar Kundu et al.   CANCER LETTERS

Interaction of Muc2 and Apc on Wnt Signaling and in Intestinal Tumorigenesis: Potential Role of Chronic Inflammation

(2008) K. Yang et al.   CANCER RESEARCH

Differential effects of resveratrol on androgen-responsive LNCaP human prostate cancer cells in vitro and in vivo

(2008) T. T.Y. Wang et al.   CARCINOGENESIS

Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span

(2008) Kevin J. Pearson et al.   Cell Metabolism

Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: Inhibition of cell proliferation and induction of apoptosis

(2008) Anupam Bishayee et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Cancer Chemoprevention Through Dietary Antioxidants: Progress and Promise

(2007) Naghma Khan et al.   ANTIOXIDANTS & REDOX SIGNALING

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL

Resveratrol induces apoptosis involving mitochondrial pathways in mouse skin tumorigenesis

(2007) Neetu Kalra et al.   LIFE SCIENCES