Autophagy in Hepatic Fibrosis

Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome

(2014) Wen-Xing Ding et al.   Autophagy

Functions of autophagy in normal and diseased liver

(2013) Mark J. Czaja et al.   Autophagy

Nilotinib induces apoptosis and autophagic cell death of activated hepatic stellate cells via inhibition of histone deacetylases

(2013) Mohamed E. Shaker et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagy promotes hepatocellular carcinoma cell invasion through activation of epithelial–mesenchymal transition

(2013) Jun Li et al.   CARCINOGENESIS

Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha-1-anti-trypsin deficiency

(2013) Nunzia Pastore et al.   EMBO Molecular Medicine

Liver autophagy: much more than just taking out the trash

(2013) Jaime L. Schneider et al.   Nature Reviews Gastroenterology & Hepatology

DEDD, a novel tumor repressor, reverses epithelial-mesenchymal transition by activating selective autophagy

(2012) Qi Lv et al.   Autophagy

Autophagy fuels tissue fibrogenesis

(2012) Virginia Hernández-Gea et al.   Autophagy

DEDD Interacts with PI3KC3 to Activate Autophagy and Attenuate Epithelial-Mesenchymal Transition in Human Breast Cancer

(2012) Q. Lv et al.   CANCER RESEARCH

Autophagy Releases Lipid That Promotes Fibrogenesis by Activated Hepatic Stellate Cells in Mice and in Human Tissues

(2012) Virginia Hernández–Gea et al.   GASTROENTEROLOGY

Interplay between bone marrow and liver in the pathogenesis of hepatic fibrosis

(2012) Yutaka Inagaki et al.   HEPATOLOGY RESEARCH

Autophagy as a macrophage response to bacterial infection

(2012) Lan Gong et al.   IUBMB LIFE

Role of Autophagy in Aging

(2012) Osamu Yamaguchi et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Hepatitis C virus related hepatocellular carcinoma: A case control study from India

(2012) Manash Pratim Sarma et al.   JOURNAL OF MEDICAL VIROLOGY

Replacement of Retinyl Esters by Polyunsaturated Triacylglycerol Species in Lipid Droplets of Hepatic Stellate Cells during Activation

(2012) Nicole Testerink et al.   PLoS One

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Autophagy stimulation by rapamycin suppresses lung inflammation and infection byBurkholderia cenocepaciain a model of cystic fibrosis

(2011) Basant A. Abdulrahman et al.   Autophagy

The Beclin 1 network regulates autophagy and apoptosis

(2011) R Kang et al.   CELL DEATH AND DIFFERENTIATION

Autophagy May Precede Cellular Senescence of Bile Ductular Cells in Ductular Reaction in Primary Biliary Cirrhosis

(2011) Motoko Sasaki et al.   DIGESTIVE DISEASES AND SCIENCES

The emerging role of autophagy in alcoholic liver disease

(2011) Wen-Xing Ding et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection

(2011) Maurizio Renna et al.   JOURNAL OF CLINICAL INVESTIGATION

A role for autophagy during hepatic stellate cell activation

(2011) Lien F.R. Thoen et al.   JOURNAL OF HEPATOLOGY

Subversion of Cellular Autophagy Machinery by Hepatitis B Virus for Viral Envelopment

(2011) J. Li et al.   JOURNAL OF VIROLOGY

The role of autophagy in unilateral ureteral obstruction rat model

(2011) WAN-YOUNG KIM et al.   NEPHROLOGY

Autophagy in the control and pathogenesis of viral infection

(2011) Brian Yordy et al.   Current Opinion in Virology

Autophagy Is a Component of Epithelial Cell Fate in Obstructive Uropathy

(2010) Ling Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Tubular Overexpression of Transforming Growth Factor-β1 Induces Autophagy and Fibrosis but Not Mesenchymal Transition of Renal Epithelial Cells

(2010) Robert Koesters et al.   AMERICAN JOURNAL OF PATHOLOGY

Autophagy in health and disease. 2. Regulation of lipid metabolism and storage by autophagy: pathophysiological implications

(2010) Mark J. Czaja   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cystic fibrosis: A disorder with defective autophagy

(2010) Alessandro Luciani et al.   Autophagy

Hepatic stellate cell (vitamin A-storing cell) and its relative – past, present and future

(2010) Haruki Senoo et al.   CELL BIOLOGY INTERNATIONAL

Rapamycin reduces intrahepatic alpha-1-antitrypsin mutant Z protein polymers and liver injury in a mouse model

(2010) Shalesh Kaushal et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice

(2010) Wen–Xing Ding et al.   GASTROENTEROLOGY

Autophagy is involved in the elimination of intracellular inclusions, Mallory-Denk bodies, in hepatocytes

(2010) Masaru Harada   Medical Molecular Morphology

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

An Autophagy-Enhancing Drug Promotes Degradation of Mutant  1-Antitrypsin Z and Reduces Hepatic Fibrosis

(2010) T. Hidvegi et al.   SCIENCE

Matrix metalloproteinases and their inhibitors as markers of inflammation and fibrosis in chronic liver disease (Review)

(2009) Mazzarino   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

The autophagy machinery is required to initiate hepatitis C virus replication

(2009) M. Dreux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagic disposal of the aggregation-prone protein that causes liver inflammation and carcinogenesis in α-1-antitrypsin deficiency

(2008) D H Perlmutter   CELL DEATH AND DIFFERENTIATION

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Autophagy in the liver

(2008) Xiao-Ming Yin et al.   HEPATOLOGY

Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression

(2008) Hong Tang et al.   HEPATOLOGY

Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response

(2008) Donna Sir et al.   HEPATOLOGY

Lipid droplets: a classic organelle with new outfits

(2008) Toyoshi Fujimoto et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Regulation of autophagy by cytoplasmic p53

(2008) Ezgi Tasdemir et al.   NATURE CELL BIOLOGY

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS