Melatonin nephroprotective action in Zucker diabetic fatty rats involves its inhibitory effect on NADPH oxidase

Therapeutic strategies of diabetic nephropathy: recent progress and future perspectives

(2015) Meng Lv et al.   DRUG DISCOVERY TODAY

ERK1/2 pathway is involved in renal gluconeogenesis inhibition under conditions of lowered NADPH oxidase activity

(2015) Katarzyna Winiarska et al.   FREE RADICAL BIOLOGY AND MEDICINE

Experimental and clinical aspects of melatonin and clock genes in diabetes

(2015) Elmar Peschke et al.   JOURNAL OF PINEAL RESEARCH

Diabetic nephropathy: landmark clinical trials and tribulations

(2015) Gary C.W. Chan et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

NADPH oxidase inhibitor, apocynin, improves renal glutathione status in Zucker diabetic fatty rats: A comparison with melatonin

(2014) Katarzyna Winiarska et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Melatonin and Renal Protection: Novel Perspectives from Animal Experiments and Human Studies (Review)

(2014) Jaroslav Hrenak et al.   CURRENT PHARMACEUTICAL DESIGN

Molecular Insights of p47phoxPhosphorylation Dynamics in the Regulation of NADPH Oxidase Activation and Superoxide Production

(2014) Daniel N. Meijles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardioprotective effects of melatonin against myocardial injuries induced by chronic intermittent hypoxia in rats

(2014) Hang-Mee Yeung et al.   JOURNAL OF PINEAL RESEARCH

Melatonin: a well-documented antioxidant with conditional pro-oxidant actions

(2014) Hong-Mei Zhang et al.   JOURNAL OF PINEAL RESEARCH

Vaspin attenuates high glucose-induced vascular smooth muscle cells proliferation and chemokinesis by inhibiting the MAPK, PI3K/Akt, and NF-κB signaling pathways

(2013) Hailing Li et al.   ATHEROSCLEROSIS

Insulin increases glomerular filtration barrier permeability through dimerization of protein kinase G type Iα subunits

(2013) Agnieszka Piwkowska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Nox as a target for diabetic complications

(2013) Yves Gorin et al.   CLINICAL SCIENCE

Valsartan slows the progression of diabetic nephropathy indb/dbmice via a reduction in podocyte injury, and renal oxidative stress and inflammation

(2013) Guangyu Zhou et al.   CLINICAL SCIENCE

Influence of melatonin receptor signalling on parameters involved in blood glucose regulation

(2013) Ivonne Bazwinsky-Wutschke et al.   JOURNAL OF PINEAL RESEARCH

Melatonin ameliorates Angiotensin II-induced vascular endothelial damage via its antioxidative properties

(2013) Tomoko Nakao et al.   JOURNAL OF PINEAL RESEARCH

Melatonin ameliorates endothelial dysfunction, vascular inflammation, and systemic hypertension in rats with chronic intermittent hypoxia

(2013) Ming-Wai Hung et al.   JOURNAL OF PINEAL RESEARCH

Advanced Glycation End Products Induce Human Corneal Epithelial Cells Apoptosis through Generation of Reactive Oxygen Species and Activation of JNK and p38 MAPK Pathways

(2013) Long Shi et al.   PLoS One

The NOX toolbox: validating the role of NADPH oxidases in physiology and disease

(2012) Sebastian Altenhöfer et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Oxidative Stress, Nox Isoforms and Complications of Diabetes—Potential Targets for Novel Therapies

(2012) Mona Sedeek et al.   Journal of Cardiovascular Translational Research

Increased Phagocyte-Like NADPH Oxidase and ROS Generation in Type 2 Diabetic ZDF Rat and Human Islets

(2011) Ismail Syed et al.   DIABETES

Telmisartan attenuates oxidative stress and renal fibrosis in streptozotocin induced diabetic mice with the alteration of angiotensin-(1–7)masreceptor expression associated with its PPAR-γ agonist action

(2011) Arun Prasath Lakshmanan et al.   FREE RADICAL RESEARCH

Melatonin improves glucose homeostasis in young Zucker diabetic fatty rats

(2011) Ahmad Agil et al.   JOURNAL OF PINEAL RESEARCH

Glucose: A vital toxin and potential utility of melatonin in protecting against the diabetic state

(2011) Ahmet Korkmaz et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Preservation of Kidney Function with Combined Inhibition of NADPH Oxidase and Angiotensin-Converting Enzyme in Diabetic Nephropathy

(2010) Vicki Thallas-Bonke et al.   AMERICAN JOURNAL OF NEPHROLOGY

Glycated albumin activates NADPH oxidase in rat mesangial cells through up-regulation of p47phox

(2010) Yanzhang Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Melatonin signaling and cell protection function

(2010) Francesca Luchetti et al.   FASEB JOURNAL

Effects of an oral adsorbent on oxidative stress and fibronectin expression in experimental diabetic nephropathy

(2010) S. H. Lee et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Puerarin attenuates high-glucose-and diabetes-induced vascular smooth muscle cell proliferation by blocking PKCβ2/Rac1-dependent signaling

(2009) Li-Hua Zhu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Diet-induced Renal Changes in Zucker Rats Are Ameliorated by the Superoxide Dismutase Mimetic TEMPOL

(2009) Philip J. Ebenezer et al.   Obesity

Effects of NADPH oxidase inhibitor on diabetic nephropathy in OLETF rats: The role of reducing oxidative stress in its protective property

(2008) Soo Min Nam et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Melatonin impairs NADPH oxidase assembly and decreases superoxide anion production in microglia exposed to amyloid-β1-42

(2008) Juefei Zhou et al.   JOURNAL OF PINEAL RESEARCH