Worms need microbes too: microbiota, health and aging inCaenorhabditis elegans

Mechanism underlying prolongevity induced by bifidobacteria in Caenorhabditis elegans

(2013) Tomomi Komura et al.   BIOGERONTOLOGY

Diet-Induced Developmental Acceleration Independent of TOR and Insulin in C. elegans

(2013) Lesley T. MacNeil et al.   CELL

Bacterial Nitric Oxide Extends the Lifespan of C. elegans

(2013) Ivan Gusarov et al.   CELL

Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome

(2013) Corinne Ferrier Maurice et al.   CELL

Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism

(2013) Filipe Cabreiro et al.   CELL

System-wide Rewiring Underlies Behavioral Differences in Predatory and Bacterial-Feeding Nematodes

(2013) Daniel J. Bumbarger et al.   CELL

Laboratory adaptedEscherichia coliK-12 becomes a pathogen ofCaenorhabditis elegansupon restoration of O antigen biosynthesis

(2013) Douglas F. Browning et al.   MOLECULAR MICROBIOLOGY

Organ-specific mediation of lifespan extension: More than a gut feeling?

(2012) Michael Rera et al.   AGEING RESEARCH REVIEWS

Population dynamics and habitat sharing of natural populations of Caenorhabditis elegans and C. briggsae

(2012) Marie-Anne Félix et al.   BMC BIOLOGY

Excessive folate synthesis limits lifespan in the C. elegans: E. coli aging model

(2012) Bhupinder Virk et al.   BMC BIOLOGY

Delayed accumulation of intestinal coliform bacteria enhances life span and stress resistance in Caenorhabditis elegans fed respiratory deficient E. coli

(2012) Fernando Gomez et al.   BMC MICROBIOLOGY

Control of intestinal bacterial proliferation in regulation of lifespan in Caenorhabditis elegans

(2012) Cynthia Portal-Celhay et al.   BMC MICROBIOLOGY

Data mining the human gut microbiota for therapeutic targets

(2012) M. Collison et al.   BRIEFINGS IN BIOINFORMATICS

The Impact of the Gut Microbiota on Human Health: An Integrative View

(2012) Jose C. Clemente et al.   CELL

Immune defense mechanisms in the Caenorhabditis elegans intestinal epithelium

(2012) Read Pukkila-Worley et al.   CURRENT OPINION IN IMMUNOLOGY

Effect of Caenorhabditis elegans age and genotype on horizontal gene transfer in intestinal bacteria

(2012) Cynthia Portal-Celhay et al.   FASEB JOURNAL

Caenorhabditis elegans Immune Conditioning with the Probiotic Bacterium Lactobacillus acidophilus Strain NCFM Enhances Gram-Positive Immune Responses

(2012) Younghoon Kim et al.   INFECTION AND IMMUNITY

The importance of being regular: Caenorhabditis elegans and Pristionchus pacificus defecation mutants are hypersusceptible to bacterial pathogens

(2012) Robbie Rae et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Prebiotic Fiber Increases Hepatic Acetyl CoA Carboxylase Phosphorylation and Suppresses Glucose-Dependent Insulinotropic Polypeptide Secretion More Effectively When Used with Metformin in Obese Rats

(2012) Kim A. Pyra et al.   JOURNAL OF NUTRITION

Gut microbiota composition correlates with diet and health in the elderly

(2012) Marcus J. Claesson et al.   NATURE

Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effects

(2012) M A Pierotti et al.   ONCOGENE

Is It Time for a Metagenomic Basis of Therapeutics?

(2012) H. J. Haiser et al.   SCIENCE

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

Antibiotics, microbiota, and immune defense

(2012) Carles Ubeda et al.   TRENDS IN IMMUNOLOGY

Escherichia coli noncoding RNAs can affect gene expression and physiology of Caenorhabditis elegans

(2012) Huijie Liu et al.   Nature Communications

The Evolution of Mutualism in Gut Microbiota Via Host Epithelial Selection

(2012) Jonas Schluter et al.   PLOS BIOLOGY

Loss of intestinal nuclei and intestinal integrity in aging C. elegans

(2011) Matthew D. McGee et al.   AGING CELL

Nutritional influences on the gut microbiota and the consequences for gastrointestinal health

(2011) Karen P. Scott et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Gut microbiota as a candidate for lifespan extension: an ecological/evolutionary perspective targeted on living organisms as metaorganisms

(2011) E. Ottaviani et al.   BIOGERONTOLOGY

Symbiosis and development: The hologenome concept

(2011) Eugene Rosenberg et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Understanding the benefit of metformin use in cancer treatment

(2011) Ryan JO Dowling et al.   BMC Medicine

A Conserved SREBP-1/Phosphatidylcholine Feedback Circuit Regulates Lipogenesis in Metazoans

(2011) Amy K. Walker et al.   CELL

Metformin slows down aging and extends life span of female SHR mice

(2011) Vladimir N. Anisimov et al.   CELL CYCLE

The potential for probiotic manipulation of the gastrointestinal microbiome

(2011) M Rauch et al.   CURRENT OPINION IN BIOTECHNOLOGY

The therapeutic potential of manipulating gut microbiota in obesity and type 2 diabetes mellitus

(2011) R. S. Kootte et al.   DIABETES OBESITY & METABOLISM

Worms, flies and four-legged friends: the applicability of biological models to the understanding of intestinal inflammatory diseases

(2011) J. Lin et al.   Disease Models & Mechanisms

C. elegans: model host and tool for antimicrobial drug discovery

(2011) J. J. Ewbank et al.   Disease Models & Mechanisms

Competition and Resilience between Founder and Introduced Bacteria in the Caenorhabditis elegans Gut

(2011) Cynthia Portal-Celhay et al.   INFECTION AND IMMUNITY

Evaluation of probiotic characteristics of newly isolated Lactobacillus spp.: Immune modulation and longevity

(2011) Jin Lee et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Use of Caenorhabditis elegans for Preselecting Lactobacillus Isolates To Control Salmonella Typhimurium

(2011) CHUNYANG WANG et al.   JOURNAL OF FOOD PROTECTION

Dietary Restriction of Caenorhabditis elegans by Axenic Culture Reflects Nutritional Requirement for Constituents Provided by Metabolically Active Microbes

(2011) I. Lenaerts et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Human nutrition, the gut microbiome and the immune system

(2011) Andrew L. Kau et al.   NATURE

Nictation, a dispersal behavior of the nematode Caenorhabditis elegans, is regulated by IL2 neurons

(2011) Harksun Lee et al.   NATURE NEUROSCIENCE

Enteric Microbiome Metabolites Correlate with Response to Simvastatin Treatment

(2011) Rima Kaddurah-Daouk et al.   PLoS One

Diet Drives Convergence in Gut Microbiome Functions Across Mammalian Phylogeny and Within Humans

(2011) B. D. Muegge et al.   SCIENCE

Drosophila Microbiome Modulates Host Developmental and Metabolic Homeostasis via Insulin Signaling

(2011) S. C. Shin et al.   SCIENCE

Effects of the gut microbiota on obesity and glucose homeostasis

(2011) Thomas Greiner et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A Decline in p38 MAPK Signaling Underlies Immunosenescence in Caenorhabditis elegans

(2011) Matthew J. Youngman et al.   PLoS Genetics

Why bacteria matter in animal development and evolution

(2010) Sebastian Fraune et al.   BIOESSAYS

Caenorhabditis elegans diet significantly affects metabolic profile, mitochondrial DNA levels, lifespan and brood size

(2010) S.N. Reinke et al.   MOLECULAR GENETICS AND METABOLISM

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

A Neuromedin U Receptor Acts with the Sensory System to Modulate Food Type-Dependent Effects on C. elegans Lifespan

(2010) Wolfgang Maier et al.   PLOS BIOLOGY

Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways inC. elegans

(2009) Eric L. Greer et al.   AGING CELL

Modulation of aging profiles in isogenic populations of Caenorhabditis elegans by bacteria causing different extrinsic mortality rates

(2009) Simon Baeriswyl et al.   BIOGERONTOLOGY

The Role of the Gut Microbiota in Energy Metabolism and Metabolic Disease

(2009) Patrice Cani et al.   CURRENT PHARMACEUTICAL DESIGN

Caenorhabditis elegans as an emerging model for studying the basic biology of obesity

(2009) K. T. Jones et al.   Disease Models & Mechanisms

Optimizing Dietary Restriction for Genetic Epistasis Analysis and Gene Discovery in C. elegans

(2009) William Mair et al.   PLoS One

The Influence of Bacterial Diet on Fat Storage in C. elegans

(2009) Kyleann K. Brooks et al.   PLoS One

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered bacterial metabolism, not coenzyme Q content, is responsible for the lifespan extension in Caenorhabditis elegans fed an Escherichia coli diet lacking coenzyme Q

(2008) Ryoichi Saiki et al.   AGING CELL

Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans

(2008) Erica D Smith et al.   BMC DEVELOPMENTAL BIOLOGY

Metformin and the intestine

(2008) C. J. Bailey et al.   DIABETOLOGIA

Mechanisms Underlying Saturable Intestinal Absorption of Metformin

(2008) W. R. Proctor et al.   DRUG METABOLISM AND DISPOSITION

Role of Spore Coat Proteins in the Resistance of Bacillus subtilis Spores to Caenorhabditis elegans Predation

(2008) M.-H. Laaberki et al.   JOURNAL OF BACTERIOLOGY

Microsporidia Are Natural Intracellular Parasites of the Nematode Caenorhabditis elegans

(2008) Emily R Troemel et al.   PLOS BIOLOGY