FGF23 promotes renal calcium reabsorption through the TRPV5 channel

FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2–SGK1 signaling pathway

(2012) Olena Andrukhova et al.   BONE

Long-TermFgf23Deficiency Does Not Influence Aging, Glucose Homeostasis, or Fat Metabolism in Mice with a Nonfunctioning Vitamin D Receptor

(2012) Carmen Streicher et al.   ENDOCRINOLOGY

Regulation and Function of the FGF23/Klotho Endocrine Pathways

(2012) Aline Martin et al.   PHYSIOLOGICAL REVIEWS

Klotho Lacks a Vitamin D Independent Physiological Role in Glucose Homeostasis, Bone Turnover, and Steady-State PTH Secretion In Vivo

(2012) René Anour et al.   PLoS One

Fibroblast Growth Factor-23-mediated Inhibition of Renal Phosphate Transport in Mice Requires Sodium-Hydrogen Exchanger Regulatory Factor-1 (NHERF-1) and Synergizes with Parathyroid Hormone

(2011) Edward J. Weinman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype

(2010) Hua Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule

(2010) Ming Chang Hu et al.   FASEB JOURNAL

WNK4 Kinase Stimulates Caveola-mediated Endocytosis of TRPV5 Amplifying the Dynamic Range of Regulation of the Channel by Protein Kinase C

(2010) Seung-Kuy Cha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FGF-23: More than a regulator of renal phosphate handling?

(2010) Harald Jüppner et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Altered renal FGF23-mediated activity involving MAPK and Wnt: effects of the Hyp mutation

(2010) Emily G Farrow et al.   JOURNAL OF ENDOCRINOLOGY

Parathyroid Hormone Activates TRPV5 via PKA-Dependent Phosphorylation

(2009) T. de Groot et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Klotho Prevents Renal Calcium Loss

(2009) R. T. Alexander et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Initial FGF23-Mediated Signaling Occurs in the Distal Convoluted Tubule

(2009) E. G. Farrow et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The role of transient receptor potential channels in kidney disease

(2009) Titia E. Woudenberg-Vrenken et al.   Nature Reviews Nephrology

WNK4 regulates the secretory pathway via which TRPV5 is targeted to the plasma membrane

(2008) Yi Jiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis

(2008) Teruyo Nakatani et al.   FASEB JOURNAL

WNK Kinases and Renal Sodium Transport in Health and Disease

(2008) James A. McCormick et al.   HYPERTENSION

Activation of cell migration with fibroblast growth factor-2 requires calcium-sensitive potassium channels

(2008) Wolfram Kessler et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1

(2008) S.-K. Cha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA