- Home
- Publications
- Publication Search
- Publication Details
Title
Regulation and Function of the FGF23/Klotho Endocrine Pathways
Authors
Keywords
-
Journal
PHYSIOLOGICAL REVIEWS
Volume 92, Issue 1, Pages 131-155
Publisher
American Physiological Society
Online
2012-02-01
DOI
10.1152/physrev.00002.2011
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Associations of Fibroblast Growth Factor 23 and Uncarboxylated Matrix Gla Protein With Mortality in Coronary Artery Disease: The Heart and Soul Study
- (2013) Benjamin D. Parker ANNALS OF INTERNAL MEDICINE
- Fibroblast Growth Factor 23 (FGF23) and Alpha-Klotho Stimulate Osteoblastic MC3T3.E1 Cell Proliferation and Inhibit Mineralization
- (2011) V. Shalhoub et al. CALCIFIED TISSUE INTERNATIONAL
- Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling
- (2011) Aline Martin et al. FASEB JOURNAL
- Airspace Enlargement With Airway Cell Apoptosis in Klotho Mice: A Model of Aging Lung
- (2011) M. Ishii et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- The secretory response of parathyroid hormone to acute hypocalcemia in vivo is independent of parathyroid glandular sodium/potassium-ATPase activity
- (2011) Giedre Martuseviciene et al. KIDNEY INTERNATIONAL
- Autosomal-Recessive Hypophosphatemic Rickets Is Associated with an Inactivation Mutation in the ENPP1 Gene
- (2010) Varda Levy-Litan et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Loss-of-Function ENPP1 Mutations Cause Both Generalized Arterial Calcification of Infancy and Autosomal-Recessive Hypophosphatemic Rickets
- (2010) Bettina Lorenz-Depiereux et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype
- (2010) Hua Li et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Circulating Fibroblast Growth Factor-23 Is Associated With Fat Mass and Dyslipidemia in Two Independent Cohorts of Elderly Individuals
- (2010) Majd A.I. Mirza et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Hormone-like (endocrine) Fgfs: their evolutionary history and roles in development, metabolism, and disease
- (2010) Nobuyuki Itoh CELL AND TISSUE RESEARCH
- Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule
- (2010) Ming Chang Hu et al. FASEB JOURNAL
- Failure to Process Dentin Matrix Protein 1 (DMP1) into Fragments Leads to Its Loss of Function in Osteogenesis
- (2010) Yao Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ASARM mineralization hypothesis: A bridge too far?
- (2010) Valentin David et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Leptin stimulates fibroblast growth factor 23 expression in bone and suppresses renal 1α,25-dihydroxyvitamin D3 synthesis in leptin-deficient ob/ob Mice
- (2010) Kiyomi Tsuji et al. JOURNAL OF BONE AND MINERAL RESEARCH
- The biological function of DMP-1 in osteocyte maturation is mediated by its 57-kDa c-terminal fragment
- (2010) Yongbo Lu et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Circulating Levels of Soluble Klotho and FGF23 in X-Linked Hypophosphatemia: Circadian Variance, Effects of Treatment, and Relationship to Parathyroid Status
- (2010) Thomas O. Carpenter et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Treatment of X-Linked Hypophosphatemia with Calcitriol and Phosphate Increases Circulating Fibroblast Growth Factor 23 Concentrations
- (2010) Erik A. Imel et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Vitamin D Status and Its Relation to Muscle Mass and Muscle Fat in Young Women
- (2010) Vicente Gilsanz et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Different Forms of DMP1 Play Distinct Roles in Mineralization
- (2010) A. Gericke et al. JOURNAL OF DENTAL RESEARCH
- FGF23 Fails to Inhibit Uremic Parathyroid Glands
- (2010) R. Canalejo et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Forging Forward with 10 Burning Questions on FGF23 in Kidney Disease
- (2010) M. Wolf JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Klotho Deficiency Causes Vascular Calcification in Chronic Kidney Disease
- (2010) M. C. Hu et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Direct evidence for a causative role of FGF23 in the abnormal renal phosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease
- (2010) Hisashi Hasegawa et al. KIDNEY INTERNATIONAL
- The role of FGF-23 in CKD-MBD and cardiovascular disease: friend or foe?
- (2010) T. E. Larsson NEPHROLOGY DIALYSIS TRANSPLANTATION
- Pilot study of dietary phosphorus restriction and phosphorus binders to target fibroblast growth factor 23 in patients with chronic kidney disease
- (2010) T. Isakova et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Relevant use of Klotho in FGF19 subfamily signaling system in vivo
- (2010) K.-i. Tomiyama et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fibroblast Growth Factor 23: A Possible Cause of Left Ventricular Hypertrophy in Hemodialysis Patients
- (2009) Heng Jung Hsu et al. AMERICAN JOURNAL OF THE MEDICAL SCIENCES
- Circulating fibroblast growth factor-23 is associated with vascular dysfunction in the community
- (2009) Majd A.I. Mirza et al. ATHEROSCLEROSIS
- Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population
- (2009) Majd A.I. Mirza et al. ATHEROSCLEROSIS
- Decreased expression of klotho gene in uremic atherosclerosis in apolipoprotein E-deficient mice
- (2009) Jie Yu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hypophosphatemia induced by intravenous administration of saccharated ferric oxide
- (2009) Yuichiro Shimizu et al. BONE
- Fibroblast Growth Factor 23 and Left Ventricular Hypertrophy in Chronic Kidney Disease
- (2009) Orlando M. Gutiérrez et al. CIRCULATION
- Early Control of PTH and FGF23 in Normophosphatemic CKD Patients: A New Target in CKD-MBD Therapy?
- (2009) R. B. Oliveira et al. Clinical Journal of the American Society of Nephrology
- Bone Formation Regulates Circulating Concentrations of Fibroblast Growth Factor 23
- (2009) Rana Samadfam et al. ENDOCRINOLOGY
- Klotho Gene Delivery Prevents the Progression of Spontaneous Hypertension and Renal Damage
- (2009) Yuhong Wang et al. HYPERTENSION
- Nuclear Isoforms of Fibroblast Growth Factor 2 Are Novel Inducers of Hypophosphatemia via Modulation of FGF23 and KLOTHO
- (2009) Liping Xiao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Defective O-Glycosylation due to a Novel Homozygous S129P Mutation Is Associated with Lack of Fibroblast Growth Factor 23 Secretion and Tumoral Calcinosis
- (2009) Clemens Bergwitz et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- FGF23 Elevation and Hypophosphatemia after Intravenous Iron Polymaltose: A Prospective Study
- (2009) Belinda J. Schouten et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The growth factor midkine regulates the renin-angiotensin system in mice
- (2009) Akinori Hobo et al. JOURNAL OF CLINICAL INVESTIGATION
- FGF23 is a putative marker for bone healing and regeneration
- (2009) Sascha Goebel et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Parathyroid Hormone Activates TRPV5 via PKA-Dependent Phosphorylation
- (2009) T. de Groot et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Indirect Regulation of PTH by Estrogens May Require FGF23
- (2009) N. Carrillo-Lopez et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Initial FGF23-Mediated Signaling Occurs in the Distal Convoluted Tubule
- (2009) E. G. Farrow et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Cholecalciferol Supplementation Alters Calcitriol-Responsive Monocyte Proteins and Decreases Inflammatory Cytokines in ESRD
- (2009) J. R. Stubbs et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease
- (2009) H. Galitzer et al. KIDNEY INTERNATIONAL
- FGF23–parathyroid interaction: implications in chronic kidney disease
- (2009) Hirotaka Komaba et al. KIDNEY INTERNATIONAL
- Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients
- (2009) Hirotaka Komaba et al. KIDNEY INTERNATIONAL
- Fibroblast Growth Factor Receptor-1 (FGFR1) Nuclear Dynamics Reveal a Novel Mechanism in Transcription Control
- (2009) Star M. Dunham-Ems et al. MOLECULAR BIOLOGY OF THE CELL
- Novel Regulators of Fgf23 Expression and Mineralization in Hyp Bone
- (2009) Shiguang Liu et al. MOLECULAR ENDOCRINOLOGY
- Relationship between circulating FGF23 and total body atherosclerosis in the community
- (2009) Majd A. I. Mirza et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Iron polymaltose-induced FGF23 elevation complicated by hypophosphataemic osteomalacia
- (2009) B. J Schouten et al. ANNALS OF CLINICAL BIOCHEMISTRY
- Matrix extracellular phosphoglycoprotein (MEPE) correlates with serum phosphorus prior to and during octreotide treatment and following excisional surgery in hypophosphatemic linear sebaceous nevus syndrome
- (2008) William H. Hoffman et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Pathogenic role of Fgf23 in Dmp1-null mice
- (2008) Shiguang Liu et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Do osteocytes contribute to bone mineral homeostasis? Osteocytic osteolysis revisited
- (2008) Anna Teti et al. BONE
- Studies of the DMP1 57-kDa Functional Domain both in vivo and in vitro
- (2008) Yongbo Lu et al. CELLS TISSUES ORGANS
- Calcimimetics as an Adjuvant Treatment for Familial Hypophosphatemic Rickets
- (2008) U. S. Alon et al. Clinical Journal of the American Society of Nephrology
- Actions and Mode of Actions of FGF19 Subfamily Members
- (2008) Seiji FUKUMOTO ENDOCRINE JOURNAL
- In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis
- (2008) Teruyo Nakatani et al. FASEB JOURNAL
- Direct Binding of Integrin αvβ3 to FGF1 Plays a Role in FGF1 Signaling
- (2008) Seiji Mori et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Exported 18-kDa Isoform of Fibroblast Growth Factor-2 Is a Critical Determinant of Bone Mass in Mice
- (2008) Liping Xiao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MEPE-ASARM Peptides Control Extracellular Matrix Mineralization by Binding to Hydroxyapatite: An Inhibition Regulated by PHEX Cleavage of ASARM
- (2008) William N Addison et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Overexpression of Fibroblast Growth Factor 23 Suppresses Osteoblast Differentiation and Matrix Mineralization In Vitro
- (2008) Hua Wang et al. JOURNAL OF BONE AND MINERAL RESEARCH
- FGFR4 and its novel splice form in myogenic cells: Interplay of glycosylation and tyrosine phosphorylation
- (2008) Boguslaw A. Kwiatkowski et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Hypophosphatemia with Elevations in Serum Fibroblast Growth Factor 23 in a Child with Jansen’s Metaphyseal Chondrodysplasia
- (2008) Whitney W. Brown et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Vitamin D Status and Its Relationship to Body Fat, Final Height, and Peak Bone Mass in Young Women
- (2008) Richard Kremer et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Endocrine functions of bone in mineral metabolism regulation
- (2008) L. Darryl Quarles JOURNAL OF CLINICAL INVESTIGATION
- Amelioration of the premature ageing-like features ofFgf-23knockout mice by genetically restoring the systemic actions of FGF-23
- (2008) S DeLuca et al. JOURNAL OF PATHOLOGY
- FGFR3 and FGFR4 Do not Mediate Renal Effects of FGF23
- (2008) S. Liu et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Estrogen downregulates the proximal tubule type IIa sodium phosphate cotransporter causing phosphate wasting and hypophosphatemia
- (2008) S. Faroqui et al. KIDNEY INTERNATIONAL
- The -glucuronidase klotho exclusively activates the epithelial Ca2+ channels TRPV5 and TRPV6
- (2008) P. Lu et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Peripheral vascular calcification in long-haemodialysis patients: associated factors and survival consequences
- (2008) G. Jean et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Fibroblast Growth Factor 23 and Mortality among Patients Undergoing Hemodialysis
- (2008) Orlando M. Gutiérrez et al. NEW ENGLAND JOURNAL OF MEDICINE
- Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer
- (2008) I Wolf et al. ONCOGENE
- Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1
- (2008) S.-K. Cha et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A translocation causing increased -Klotho level results in hypophosphatemic rickets and hyperparathyroidism
- (2008) C. A. Brownstein et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Calcimimetics or vitamin D analogs for suppressing parathyroid hormone in end-stage renal disease: time for a paradigm shift?
- (2008) James B Wetmore et al. Nature clinical practice. Nephrology
- Genetic Evidence of Serum Phosphate-Independent Functions of FGF-23 on Bone
- (2008) Despina Sitara et al. PLoS Genetics
- FGF23 is elevated in Gambian children with rickets
- (2007) Ann Prentice et al. BONE
- Degradation of MEPE, DMP1, and Release of SIBLING ASARM-Peptides (Minhibins): ASARM-Peptide(s) Are Directly Responsible for Defective Mineralization in HYP
- (2007) Aline Martin et al. ENDOCRINOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started