Mechanism-based Inhibition Profiles of Erythromycin and Clarithromycin with Cytochrome P450 3A4 Genetic Variants

Comparison of the Inhibitory Profiles of Itraconazole and Cimetidine in Cytochrome P450 3A4 Genetic Variants

(2011) T. Akiyoshi et al.   DRUG METABOLISM AND DISPOSITION

Peripheral Ligand-binding Site in Cytochrome P450 3A4 Located with Fluorescence Resonance Energy Transfer (FRET)

(2011) Dmitri R. Davydov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prediction of Drug-Drug Interactions based on Time-Dependent Inhibition from High Throughput Screening of Cytochrome P450 3A4 Inhibition

(2010) Nobuo Sekiguchi et al.   Drug Metabolism and Pharmacokinetics

Inhibitory Effects of Phyllanthus amarus and Its Major Lignans on Human Microsomal Cytochrome P450 Activities: Evidence for CYP3A4 Mechanism-Based Inhibition

(2010) Theerada Taesotikul et al.   Drug Metabolism and Pharmacokinetics

A Framework for Assessing Inter-individual Variability in Pharmacokinetics Using Virtual Human Populations and Integrating General Knowledge of Physical Chemistry, Biology, Anatomy, Physiology and Genetics: A Tale of ‘Bottom-Up’ vs ‘Top-Down’ Recognition of Covariates

(2009) Masoud Jamei et al.   Drug Metabolism and Pharmacokinetics

Application of mechanism-based CYP inhibition for predicting drug–drug interactions

(2009) Zhi-Wei Zhou et al.   Expert Opinion on Drug Metabolism & Toxicology

Defective Activity of Recombinant Cytochromes P450 3A4.2 and 3A4.16 in Oxidation of Midazolam, Nifedipine, and Testosterone

(2008) M. Miyazaki et al.   DRUG METABOLISM AND DISPOSITION

Cytochrome P450 and Chemical Toxicology

(2007) F. Peter Guengerich   CHEMICAL RESEARCH IN TOXICOLOGY