Enhancing and Extending Biological Performance and Resilience

Intermittent metabolic switching, neuroplasticity and brain health

(2018) Mark P. Mattson et al.   NATURE REVIEWS NEUROSCIENCE

Remembering Pathogen Dose: Long-Term Adaptation in Innate Immunity

(2018) Michael Bauer et al.   TRENDS IN IMMUNOLOGY

Total sulfane sulfur bioavailability reflects ethnic and gender disparities in cardiovascular disease

(2018) Saurabh Rajpal et al.   Redox Biology

Compensatory mechanisms in Parkinson's disease: Circuits adaptations and role in disease modification

(2017) Javier Blesa et al.   EXPERIMENTAL NEUROLOGY

Adaptive responses of neuronal mitochondria to bioenergetic challenges: Roles in neuroplasticity and disease resistance

(2017) Sophia M. Raefsky et al.   FREE RADICAL BIOLOGY AND MEDICINE

Impact of remote ischaemic preconditioning on major clinical outcomes in patients undergoing cardiovascular surgery: A meta-analysis with trial sequential analysis of 32 randomised controlled trials

(2017) Shifei Wang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Remote Ischemic Conditioning for Patients With STEMI

(2017) Michael Rahbek Schmidt et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Repetitive Intermittent Hypoxia and Locomotor Training Enhances Walking Function in Incomplete Spinal Cord Injury Subjects: A Randomized, Triple-Blind, Placebo-Controlled Clinical Trial

(2017) Angela Navarrete-Opazo et al.   JOURNAL OF NEUROTRAUMA

Cis and trans determinants of epigenetic silencing by Polycomb repressive complex 2 in Arabidopsis

(2017) Jun Xiao et al.   NATURE GENETICS

Effects of acute intermittent hypoxia on hand use after spinal cord trauma

(2017) Randy D. Trumbower et al.   NEUROLOGY

The jasmonic acid-signalling and abscisic acid-signalling pathways cross talk during one, but not repeated, dehydration stress: a non-specific ‘panicky’ or a meaningful response?

(2017) Zoya Avramova   PLANT CELL AND ENVIRONMENT

Health consequences of electric lighting practices in the modern world: A report on the National Toxicology Program's workshop on shift work at night, artificial light at night, and circadian disruption

(2017) Ruth M. Lunn et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Remote Ischemic Conditioning May Improve Outcomes of Patients With Cerebral Small-Vessel Disease

(2017) Yuan Wang et al.   STROKE

Silver nanoparticles induce hormesis in A549 human epithelial cells

(2017) Mireille M.J.P.E. Sthijns et al.   TOXICOLOGY IN VITRO

Plant Hormesis Management with Biostimulants of Biotic Origin in Agriculture

(2017) Marcela Vargas-Hernandez et al.   Frontiers in Plant Science

Exercise, oxidants, and antioxidants change the shape of the bell-shaped hormesis curve

(2017) Zsolt Radak et al.   Redox Biology

Biochemical signaling by remote ischemic conditioning of the arm versus thigh: Is one raise of the cuff enough?

(2017) Cameron Dezfulian et al.   Redox Biology

The remote ischemic preconditioning algorithm: effect of number of cycles, cycle duration and effector organ mass on efficacy of protection

(2016) Jacob Johnsen et al.   BASIC RESEARCH IN CARDIOLOGY

Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise and Metabolic and Excitatory Challenges

(2016) Aiwu Cheng et al.   Cell Metabolism

Novel ketone diet enhances physical and cognitive performance

(2016) Andrew J. Murray et al.   FASEB JOURNAL

Microvesicles and exosomes: new players in metabolic and cardiovascular disease

(2016) Charlotte Lawson et al.   JOURNAL OF ENDOCRINOLOGY

3-Hydroxybutyrate regulates energy metabolism and induces BDNF expression in cerebral cortical neurons

(2016) Krisztina Marosi et al.   JOURNAL OF NEUROCHEMISTRY

Average Temperature, Diurnal Temperature Variation, and Stroke Hospitalizations

(2016) Judith H. Lichtman et al.   Journal of Stroke & Cerebrovascular Diseases

How compensation breaks down in Parkinson's disease: Insights from modeling of denervated striatum

(2016) Charlotte Amalie Navntoft et al.   MOVEMENT DISORDERS

Preconditioning is hormesis part II: How the conditioning dose mediates protection: Dose optimization within temporal and mechanistic frameworks

(2016) Edward J. Calabrese   PHARMACOLOGICAL RESEARCH

Preconditioning is hormesis part I: Documentation, dose-response features and mechanistic foundations

(2016) Edward J. Calabrese   PHARMACOLOGICAL RESEARCH

Psychological resilience and the gene regulatory impact of posttraumatic stress in Nepali child soldiers

(2016) Brandon A. Kohrt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian time signatures of fitness and disease

(2016) Joseph Bass et al.   SCIENCE

Sleep Is Critical for Remote Preconditioning-Induced Neuroprotection

(2016) Allison J. Brager et al.   SLEEP

Average Temperature, Diurnal Temperature Variation, and Stroke Hospitalizations

(2016) Judith H. Lichtman et al.   Journal of Stroke & Cerebrovascular Diseases

Blood transcriptome changes after stroke in an African American population

(2016) Robert Meller et al.   Annals of Clinical and Translational Neurology

Sleep Is Critical for Remote Preconditioning-Induced Neuroprotection

(2016) Allison J. Brager et al.   SLEEP

Preconditioning Strategies to Enhance Physical Performance on the Day of Competition

(2016) Liam P. Kilduff et al.   International Journal of Sports Physiology and Performance

Effect of Ischemic Preconditioning on Land-Based Sprinting in Team-Sport Athletes

(2016) Neil Gibson et al.   International Journal of Sports Physiology and Performance

Lifelong brain health is a lifelong challenge: From evolutionary principles to empirical evidence

(2015) Mark P. Mattson   AGEING RESEARCH REVIEWS

Interval exercise, but not endurance exercise, prevents endothelial ischemia-reperfusion injury in healthy subjects

(2015) Joost P. H. Seeger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Methionine restriction and life-span control

(2015) Byung Cheon Lee et al.   Annals of the New York Academy of Sciences

From Protecting the Heart to Improving Athletic Performance – the Benefits of Local and Remote Ischaemic Preconditioning

(2015) Vikram Sharma et al.   CARDIOVASCULAR DRUGS AND THERAPY

Promoting Health and Longevity through Diet: From Model Organisms to Humans

(2015) Luigi Fontana et al.   CELL

Endogenous Hydrogen Sulfide Production Is Essential for Dietary Restriction Benefits

(2015) Christopher Hine et al.   CELL

Remote Ischemic Preconditioning-Mediated Neuroprotection against Stroke is Associated with Significant Alterations in Peripheral Immune Responses

(2015) Zong-Jian Liu et al.   CNS Neuroscience & Therapeutics

Calorie restriction and methionine restriction in control of endogenous hydrogen sulfide production by the transsulfuration pathway

(2015) Christopher Hine et al.   EXPERIMENTAL GERONTOLOGY

Hormesis within a mechanistic context

(2015) Edward J. Calabrese   Homeopathy

Remote Ischemic Conditioning

(2015) Gerd Heusch et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity

(2015) Eric Ravussin et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

(2015) Tiia Ngandu et al.   LANCET

The Effect of Ischemic Preconditioning on Repeated Sprint Cycling Performance

(2015) STEPHEN D. PATTERSON et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Ischemic Conditioning Is Safe and Effective for Octo- and Nonagenarians in Stroke Prevention and Treatment

(2015) Ran Meng et al.   Neurotherapeutics

Transcriptional ‘memory’ of a stress: transient chromatin and memory (epigenetic) marks at stress-response genes

(2015) Zoya Avramova   PLANT JOURNAL

The Synthetic Elicitor 2-(5-Bromo-2-Hydroxy-Phenyl)-Thiazolidine-4-Carboxylic Acid Links Plant Immunity to Hormesis

(2015) Melinda Rodriguez-Salus et al.   PLANT PHYSIOLOGY

The Impact of High-Intensity Interval Training Versus Moderate-Intensity Continuous Training on Vascular Function: a Systematic Review and Meta-Analysis

(2015) Joyce S. Ramos et al.   SPORTS MEDICINE

Intermittent cycles of remote ischemic preconditioning augment diabetic foot ulcer healing

(2015) Gad Shaked et al.   WOUND REPAIR AND REGENERATION

Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression

(2015) Pedro Mejia et al.   Nature Communications

Extending Injury- and Disease-Resistant CNS Phenotypes by Repetitive Epigenetic Conditioning

(2015) Jeffrey M. Gidday   Frontiers in Neurology

Seven-Day Remote Ischemic Preconditioning Improves Local and Systemic Endothelial Function and Microcirculation in Healthy Humans

(2014) H. Jones et al.   AMERICAN JOURNAL OF HYPERTENSION

Muscle Mass Index As a Predictor of Longevity in Older Adults

(2014) Preethi Srikanthan et al.   AMERICAN JOURNAL OF MEDICINE

Repeated daily dosing with sildenafil provides sustained protection from endothelial dysfunction caused by ischemia and reperfusion: a human in vivo study

(2014) Kelsey McLaughlin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

MicroRNA-144 is a circulating effector of remote ischemic preconditioning

(2014) Jing Li et al.   BASIC RESEARCH IN CARDIOLOGY

Pre and post-injury environmental enrichment effects functional recovery following medial frontal cortical contusion injury in rats

(2014) Justin Jacqmain et al.   BEHAVIOURAL BRAIN RESEARCH

Adaptation to acrolein through upregulating the protection by glutathione in human bronchial epithelial cells: The materialization of the hormesis concept

(2014) Mireille M.J.P.E. Sthijns et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitohormesis

(2014) Jeanho Yun et al.   Cell Metabolism

Circulating Nitrite Contributes to Cardioprotection by Remote Ischemic Preconditioning

(2014) Tienush Rassaf et al.   CIRCULATION RESEARCH

Trained Immunity or Tolerance: Opposing Functional Programs Induced in Human Monocytes after Engagement of Various Pattern Recognition Receptors

(2014) Daniela C. Ifrim et al.   Clinical and Vaccine Immunology

Innate immune memory: towards a better understanding of host defense mechanisms

(2014) Jessica Quintin et al.   CURRENT OPINION IN IMMUNOLOGY

Challenging Oneself Intermittently to Improve Health

(2014) Mark P. Mattson   Dose-Response

Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS)

(2014) Michael Ristow et al.   Dose-Response

Association between clinical presentations before myocardial infarction and coronary mortality: a prospective population-based study using linked electronic records

(2014) Emily Herrett et al.   EUROPEAN HEART JOURNAL

Biomarkers for Ischemic Preconditioning: Finding the Responders

(2014) Sebastian Koch et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles

(2014) Zoltán Giricz et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Time-restricted feeding and the realignment of biological rhythms: translational opportunities and challenges

(2014) Jag Sunderram et al.   Journal of Translational Medicine

The role of low-grade inflammation and metabolic flexibility in aging and nutritional modulation thereof: A systems biology approach

(2014) Dulce Calçada et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Enhanced Retinal Ganglion Cell Survival in Glaucoma by Hypoxic Postconditioning After Disease Onset

(2014) Jeffrey M. Gidday et al.   Neurotherapeutics

Herbicides and plant hormesis

(2014) Regina G Belz et al.   PEST MANAGEMENT SCIENCE

Meal frequency and timing in health and disease

(2014) Mark P. Mattson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

The fifth dimension of innate immunity

(2014) C. Schmidt et al.   Journal of Cell Communication and Signaling

Nitrite in organ protection

(2013) Tienush Rassaf et al.   BRITISH JOURNAL OF PHARMACOLOGY

High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis

(2013) Kassia S Weston et al.   BRITISH JOURNAL OF SPORTS MEDICINE

Physical exercise and executive functions in preadolescent children, adolescents and young adults: a meta-analysis

(2013) Lot Verburgh et al.   BRITISH JOURNAL OF SPORTS MEDICINE

Altered Circadian Rhythmicity in Patients in the ICU

(2013) Joost A.C. Gazendam et al.   CHEST

Preinfarction Angina Reduces Infarct Size in ST-Elevation Myocardial Infarction Treated With Percutaneous Coronary Intervention

(2013) Ronald Reiter et al.   Circulation-Cardiovascular Interventions

Review of the Role of Exercise in Improving Quality of Life in Healthy Individuals and in Those With Chronic Diseases

(2013) Tedd Mitchell et al.   Current Sports Medicine Reports

Biphasic dose responses in biology, toxicology and medicine: Accounting for their generalizability and quantitative features

(2013) Edward J. Calabrese   ENVIRONMENTAL POLLUTION

Improved long-term clinical outcomes in patients with ST-elevation myocardial infarction undergoing remote ischaemic conditioning as an adjunct to primary percutaneous coronary intervention

(2013) Astrid D. Sloth et al.   EUROPEAN HEART JOURNAL

Remote ischemic preconditioning protects neurocognitive function of rats following cerebral hypoperfusion

(2013) Tao Xu et al.   MEDICAL SCIENCE MONITOR

Late exercise reduces neuroinflammation and cognitive dysfunction after traumatic brain injury

(2013) Chun-Shu Piao et al.   NEUROBIOLOGY OF DISEASE

Daily intermittent hypoxia enhances walking after chronic spinal cord injury: A randomized trial

(2013) H. B. Hayes et al.   NEUROLOGY

Preconditioning the Human Brain

(2013) Sebastian Koch et al.   STROKE

Using transcranial electrical stimulation to enhance cognitive functions in the typical and atypical brain

(2013) Roi Kadosh   Translational Neuroscience

Remote ischemic preconditioning prevents reduction in brachial artery flow-mediated dilation after strenuous exercise

(2012) Tom G. Bailey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Pathobiology of injury after stroke: the neurovascular unit and beyond

(2012) Ulrich Dirnagl   Annals of the New York Academy of Sciences

Exercise-induced cardioprotection is mediated by a bloodborne, transferable factor

(2012) M. M. Michelsen et al.   BASIC RESEARCH IN CARDIOLOGY

Release of a humoral circulating cardioprotective factor by remote ischemic preconditioning is dependent on preserved neural pathways in diabetic patients

(2012) Rebekka Vibjerg Jensen et al.   BASIC RESEARCH IN CARDIOLOGY

Effects of aging and methionine restriction applied at old age on ROS generation and oxidative damage in rat liver mitochondria

(2012) Inés Sanchez-Roman et al.   BIOGERONTOLOGY

Noninvasive limb remote ischemic preconditioning contributes neuroprotective effects via activation of adenosine A1 receptor and redox status after transient focal cerebral ischemia in rats

(2012) Sheng Hu et al.   BRAIN RESEARCH

Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes

(2012) Jessica Quintin et al.   Cell Host & Microbe

Energy Intake and Exercise as Determinants of Brain Health and Vulnerability to Injury and Disease

(2012) Mark P. Mattson   Cell Metabolism

Adaptive radiation-induced epigenetic alterations mitigated by antioxidants

(2012) Autumn J. Bernal et al.   FASEB JOURNAL

PGC-1α and exercise in the control of body weight

(2012) S Summermatter et al.   INTERNATIONAL JOURNAL OF OBESITY

Pleiotropic-Acting Nutrients Require Integrative Investigational Approaches: The Example of Flavonoids

(2012) Antje R. Weseler et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Remote ischemic conditioning

(2012) Michael R. Schmidt et al.   Journal of Cardiovascular Medicine

Repetitive Intermittent Hypoxia Induces Respiratory and Somatic Motor Recovery after Chronic Cervical Spinal Injury

(2012) M. R. Lovett-Barr et al.   JOURNAL OF NEUROSCIENCE

Ischemic tolerance in the brain: Endogenous adaptive machinery against ischemic stress

(2012) Kazuo Kitagawa   JOURNAL OF NEUROSCIENCE RESEARCH

A review of multidomain interventions to support healthy cognitive ageing

(2012) N. Schneider et al.   Journal of Nutrition Health & Aging

Effect of taurine and N-acetylcysteine on methionine restriction-mediated adiposity resistance

(2012) Amany K. Elshorbagy et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Unknown

(2012) Yanli Zhu et al.   MOLECULAR MEDICINE

A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease

(2012) Yoshihiro Kashiwaya et al.   NEUROBIOLOGY OF AGING

Upper limb ischemic preconditioning prevents recurrent stroke in intracranial arterial stenosis

(2012) R. Meng et al.   NEUROLOGY

Long-term exercise treatment reduces oxidative stress in the hippocampus of aging rats

(2012) K. Marosi et al.   NEUROSCIENCE

Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed

(2012) Rui Wang   PHYSIOLOGICAL REVIEWS

The Chronic Protective Effects of Limb Remote Preconditioning and the Underlying Mechanisms Involved in Inflammatory Factors in Rat Stroke

(2012) Dingtai Wei et al.   PLoS One

Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection

(2012) Meijuan Zhang et al.   PROGRESS IN NEUROBIOLOGY

Involvement of PGC-1α in the formation and maintenance of neuronal dendritic spines

(2012) Aiwu Cheng et al.   Nature Communications

Multiple exposures to drought 'train' transcriptional responses in Arabidopsis

(2012) Yong Ding et al.   Nature Communications

Repetitive hypoxia extends endogenous neurovascular protection for stroke

(2011) Ann M. Stowe et al.   ANNALS OF NEUROLOGY

Longitudinal evolution of compensatory changes in striatal dopamine processing in Parkinson's disease

(2011) Ramachandiran Nandhagopal et al.   BRAIN

Neurogenic pathway mediated remote preconditioning protects the brain from transient focal ischemic injury

(2011) Samit Malhotra et al.   BRAIN RESEARCH

Remote Ischemic Preconditioning Protects the Brain Against Injury After Hypothermic Circulatory Arrest

(2011) Hanna A. Jensen et al.   CIRCULATION

Repeated Remote Ischemic Postconditioning Protects Against Adverse Left Ventricular Remodeling and Improves Survival in a Rat Model of Myocardial Infarction

(2011) Meng Wei et al.   CIRCULATION RESEARCH

Biphasic Dose Response in Low Level Light Therapy – an Update

(2011) Ying-Ying Huang et al.   Dose-Response

Ischemic preconditioning of the muscle improves maximal exercise performance but not maximal oxygen uptake in humans

(2011) Antonio Crisafulli et al.   JOURNAL OF APPLIED PHYSIOLOGY

Normobaric hypoxia conditioning reduces blood pressure and normalizes nitric oxide synthesis in patients with arterial hypertension

(2011) Nadezhda P. Lyamina et al.   JOURNAL OF HYPERTENSION

Pleiotropic Benefit of Monomeric and Oligomeric Flavanols on Vascular Health - A Randomized Controlled Clinical Pilot Study

(2011) Antje R. Weseler et al.   PLoS One

The hormesis database: The occurrence of hormetic dose responses in the toxicological literature

(2011) Edward J. Calabrese et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Remote Ischemic Limb Preconditioning After Subarachnoid Hemorrhage

(2011) Sebastian Koch et al.   STROKE

Remote Ischemic Per-Conditioning

(2011) Cecil D. Hahn et al.   STROKE

Influence of pre-infarction angina, collateral flow, and pre-procedural TIMI flow on myocardial salvage index by cardiac magnetic resonance in patients with ST-segment elevation myocardial infarction

(2011) J. Lonborg et al.   European Heart Journal-Cardiovascular Imaging

The hydrogen sulfide signaling system: changes during aging and the benefits of caloric restriction

(2010) Benjamin L. Predmore et al.   AGE

Remote Ischemic Conditioning in Patients With Myocardial Infarction Treated With Primary Angioplasty

(2010) Kim Munk et al.   Circulation-Cardiovascular Imaging

Lethal intergroup aggression leads to territorial expansion in wild chimpanzees

(2010) John C. Mitani et al.   CURRENT BIOLOGY

Imaging of compensatory mechanisms in Parkinsonʼs disease

(2010) Silke Appel-Cresswell et al.   CURRENT OPINION IN NEUROLOGY

Parthenin hormesis in plants depends on growth conditions

(2010) Regina G. Belz et al.   ENVIRONMENTAL AND EXPERIMENTAL BOTANY

Hormesis is central to toxicology, pharmacology and risk assessment

(2010) Edward J Calabrese   HUMAN & EXPERIMENTAL TOXICOLOGY

The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women

(2010) M N Harvie et al.   INTERNATIONAL JOURNAL OF OBESITY

Ischemic Preconditioning Regulates Expression of microRNAs and a Predicted Target, MeCP2, in Mouse Cortex

(2010) Theresa A Lusardi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Honoring Clive McCay and 75 Years of Calorie Restriction Research

(2010) Roger B. McDonald et al.   JOURNAL OF NUTRITION

Remote ischaemic conditioning before hospital admission, as a complement to angioplasty, and effect on myocardial salvage in patients with acute myocardial infarction: a randomised trial

(2010) Hans Erik Bøtker et al.   LANCET

Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease

(2010) Dimitrios Kapogiannis et al.   LANCET NEUROLOGY

Remote Preconditioning Improves Maximal Performance in Highly Trained Athletes

(2010) EMILIE JEAN-ST-MICHEL et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Polycomb Group Proteins as Epigenetic Mediators of Neuroprotection in Ischemic Tolerance

(2010) M. Stapels et al.   Science Signaling

What are biomarkers?

(2010) Kyle Strimbu et al.   Current Opinion in HIV and AIDS

Maternal Ethanol Consumption Alters the Epigenotype and the Phenotype of Offspring in a Mouse Model

(2010) Nina Kaminen-Ahola et al.   PLoS Genetics

Short-term dietary restriction and fasting precondition against ischemia reperfusion injury in mice

(2009) James R. Mitchell et al.   AGING CELL

5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside Increases Myocardial Glucose Uptake during Reperfusion and Induces Late Pre-conditioning: Potential Role of AMP-Activated Protein Kinase

(2009) Steen B. Kristiansen et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Transient limb ischaemia remotely preconditions through a humoral mechanism acting directly on the myocardium: evidence suggesting cross-species protection

(2009) Mikiko Shimizu et al.   CLINICAL SCIENCE

Awareness of Hormesis Will Enhance Future Research in Basic and Applied Neuroscience

(2009) Mark P. Mattson   CRITICAL REVIEWS IN TOXICOLOGY

Ischemic preconditioning improves maximal performance in humans

(2009) Patricia C. E. de Groot et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Multiple mild heat-shocks decrease the Gompertz component of mortality in Caenorhabditis elegans

(2009) Deqing Wu et al.   EXPERIMENTAL GERONTOLOGY

Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice

(2009) Alexis M. Stranahan et al.   HIPPOCAMPUS

Translation of remote ischaemic preconditioning into clinical practice

(2009) Rajesh K Kharbanda et al.   LANCET

What is health? The ability to adapt

(2009) The Lancet   LANCET

Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use

(2009) Ulrich Dirnagl et al.   LANCET NEUROLOGY

Mechanisms compensating for dopamine loss in early Parkinson disease

(2009) J. Brotchie et al.   NEUROLOGY

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

(2009) R. J. Colman et al.   SCIENCE

Lovastatin interferes with the infarct size-limiting effect of ischemic preconditioning and postconditioning in rat hearts

(2008) Gabriella F. Kocsis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

PI3Kγ controls oxidative bursts in neutrophils via interactions with PKCα and p47phox

(2008) Katja Lehmann et al.   BIOCHEMICAL JOURNAL

The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies

(2008) Marwan Maalouf et al.   BRAIN RESEARCH REVIEWS

Remote ischaemic preconditioning: underlying mechanisms and clinical application

(2008) D. J. Hausenloy et al.   CARDIOVASCULAR RESEARCH

Environmental epigenomics in human health and disease

(2008) Dana C. Dolinoy et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Transient Ischemic Attack Before Nonlacunar Ischemic Stroke in the Elderly

(2008) David Della Morte et al.   Journal of Stroke & Cerebrovascular Diseases

Compensatory mechanisms in Parkinson's disease

(2008) Jose A. Obeso et al.   MOVEMENT DISORDERS

Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons

(2008) Alexis M Stranahan et al.   NATURE NEUROSCIENCE

Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways

(2008) Eva M. Jimenez-Mateos et al.   NEUROBIOLOGY OF DISEASE

Hormetic Dietary Phytochemicals

(2008) Tae Gen Son et al.   NEUROMOLECULAR MEDICINE

Endogenous neuroprotection: Mitochondria as gateways to cerebral preconditioning?

(2008) Ulrich Dirnagl et al.   NEUROPHARMACOLOGY

Limb remote-preconditioning protects against focal ischemia in rats and contradicts the dogma of therapeutic time windows for preconditioning

(2008) C. Ren et al.   NEUROSCIENCE

Transcriptional mechanisms of addiction: role of  FosB

(2008) E. J Nestler   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine  -Lyase

(2008) G. Yang et al.   SCIENCE

Delayed Tolerance With Repetitive Transient Focal Ischemic Preconditioning in the Mouse

(2008) Jian Zhang et al.   STROKE

Converging concepts: Adaptive response, preconditioning, and the Yerkes–Dodson Law are manifestations of hormesis

(2007) Edward J. Calabrese   AGEING RESEARCH REVIEWS