Functional relevance of genes implicated by obesity genome-wide association study signals for human adipocyte biology

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human

(2012) Atsuhiko Ichimura et al.   NATURE

Differential coexpression analysis of obesity-associated networks in human subcutaneous adipose tissue

(2011) A J Walley et al.   INTERNATIONAL JOURNAL OF OBESITY

MTCH2 in Human White Adipose Tissue and Obesity

(2011) Agné Kulyté et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Weighing in the Role of BDNF in the Central Control of Eating Behavior

(2011) Joshua Cordeira et al.   MOLECULAR NEUROBIOLOGY

Potential therapeutic uses of BDNF in neurological and psychiatric disorders

(2011) Alan H. Nagahara et al.   NATURE REVIEWS DRUG DISCOVERY

Forming functional fat: a growing understanding of adipocyte differentiation

(2011) Ana G. Cristancho et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Expression of New Loci Associated With Obesity in Diet-Induced Obese Rats: From Genetics to Physiology

(2011) Ruth Gutierrez-Aguilar et al.   Obesity

Impact of Metabolic Regulators on the Expression of the Obesity Associated Genes FTO and NAMPT in Human Preadipocytes and Adipocytes

(2011) Daniela Friebe et al.   PLoS One

Metagenomic systems biology of the human gut microbiome reveals topological shifts associated with obesity and inflammatory bowel disease

(2011) S. Greenblum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PPARγ in adipocyte differentiation and metabolism - Novel insights from genome-wide studies

(2010) Rasmus Siersbaek et al.   FEBS LETTERS

Npc1 haploinsufficiency promotes weight gain and metabolic features associated with insulin resistance

(2010) D. Jelinek et al.   HUMAN MOLECULAR GENETICS

Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation

(2010) Keizo Nishikawa et al.   JOURNAL OF CLINICAL INVESTIGATION

The small molecule phenamil is a modulator of adipocyte differentiation and PPARγ expression

(2010) Kye Won Park et al.   JOURNAL OF LIPID RESEARCH

MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria

(2010) Yehudit Zaltsman et al.   NATURE CELL BIOLOGY

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups

(2010) André Scherag et al.   PLoS Genetics

Loss-of-Function Mutation in the Dioxygenase-Encoding FTO Gene Causes Severe Growth Retardation and Multiple Malformations

(2009) Sarah Boissel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden

(2009) Frida Renström et al.   HUMAN MOLECULAR GENETICS

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations

(2009) David Meyre et al.   NATURE GENETICS

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution

(2009) Cecilia M. Lindgren et al.   PLoS Genetics

NRXN3 Is a Novel Locus for Waist Circumference: A Genome-Wide Association Study from the CHARGE Consortium

(2009) Nancy L. Heard-Costa et al.   PLoS Genetics

IgLON cell adhesion molecule Kilon is a crucial modulator for synapse number in hippocampal neurons

(2008) Takashi Hashimoto et al.   BRAIN RESEARCH

Transmembrane Protein 18 Enhances the Tropism of Neural Stem Cells for Glioma Cells

(2008) J. Jurvansuu et al.   CANCER RESEARCH

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

(2008) Gudmar Thorleifsson et al.   NATURE GENETICS

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

(2008) Cristen J Willer et al.   NATURE GENETICS

High-Resolution Mapping of Expression-QTLs Yields Insight into Human Gene Regulation

(2008) Jean-Baptiste Veyrieras et al.   PLoS Genetics