Impact of Metabolic Regulators on the Expression of the Obesity Associated Genes FTO and NAMPT in Human Preadipocytes and Adipocytes

The obesity-associated Fto gene is a transcriptional coactivator

(2010) Qiong Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Downregulation of the Longevity-Associated Protein Sirtuin 1 in Insulin Resistance and Metabolic Syndrome: Potential Biochemical Mechanisms

(2010) S. V. de Kreutzenberg et al.   DIABETES

Fasting promotes the expression of SIRT1, an NAD+-dependent protein deacetylase, via activation of PPARα in mice

(2010) Satoru Hayashida et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Crystal structure of the FTO protein reveals basis for its substrate specificity

(2010) Zhifu Han et al.   NATURE

Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats

(2010) Yi-Chun Loraine Tung et al.   PLoS One

The Fat Mass and Obesity Associated Gene FTO Functions in the Brain to Regulate Postnatal Growth in Mice

(2010) Xue Gao et al.   PLoS One

Loss-of-Function Mutation in the Dioxygenase-Encoding FTO Gene Causes Severe Growth Retardation and Multiple Malformations

(2009) Sarah Boissel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Nicotinamide Phosphoribosyltransferase Regulates Cell Survival Through NAD + Synthesis in Cardiac Myocytes

(2009) Chiao-Po Hsu et al.   CIRCULATION RESEARCH

Regulation and Function of FTO mRNA Expression in Human Skeletal Muscle and Subcutaneous Adipose Tissue

(2009) L. G. Grunnet et al.   DIABETES

Genetic Variation at the FTO Locus Influences RBL2 Gene Expression

(2009) J. B.M. Jowett et al.   DIABETES

Pre-B cell colony enhancing factor/NAMPT/visfatin and its role in inflammation-related bone disease

(2009) Alexander R. Moschen et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

A Mouse Model for the Metabolic Effects of the Human Fat Mass and Obesity Associated FTO Gene

(2009) Chris Church et al.   PLoS Genetics

Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt

(2008) Marcella Fulco et al.   DEVELOPMENTAL CELL

The Obesity Gene, FTO, Is of Ancient Origin, Up-Regulated during Food Deprivation and Expressed in Neurons of Feeding-Related Nuclei of the Brain

(2008) Robert Fredriksson et al.   ENDOCRINOLOGY

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

(2008) Guifang Jia et al.   FEBS LETTERS

An Obesity-AssociatedFTOGene Variant and Increased Energy Intake in Children

(2008) Joanne E. Cecil et al.   NEW ENGLAND JOURNAL OF MEDICINE

Polymorphisms of theFTOGene Are Associated With Variation in Energy Intake, but not Energy Expenditure

(2008) John R. Speakman et al.   Obesity

The FTO Obesity Gene. Genotyping and Gene Expression Analysis in Morbidly Obese Patients

(2008) Carina Zabena et al.   OBESITY SURGERY