Glimpse into Hox and tale regulation of cell differentiation and reprogramming

The animal body plan, the prototypic body segment, and eye evolution

(2015) Walter J. Gehring   EVOLUTION & DEVELOPMENT

Dynamic Chromatin Remodeling Mediated by Polycomb Proteins Orchestrates Pancreatic Differentiation of Human Embryonic Stem Cells

(2013) Ruiyu Xie et al.   Cell Stem Cell

Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence

(2013) E. Rodriguez-Seguel et al.   GENES & DEVELOPMENT

Analysis of the DNA-Binding Profile and Function of TALE Homeoproteins Reveals Their Specialization and Specific Interactions with Hox Genes/Proteins

(2013) Dmitry Penkov et al.   Cell Reports

A Temporal Chromatin Signature in Human Embryonic Stem Cells Identifies Regulators of Cardiac Development

(2012) Sharon L. Paige et al.   CELL

Dynamic and Coordinated Epigenetic Regulation of Developmental Transitions in the Cardiac Lineage

(2012) Joseph A. Wamstad et al.   CELL

Induced Pluripotent Stem Cells: Past, Present, and Future

(2012) Shinya Yamanaka   Cell Stem Cell

Cooperative and antagonistic roles for Irx3 and Irx5 in cardiac morphogenesis and postnatal physiology

(2012) N. Gaborit et al.   DEVELOPMENT

Regulation of retinal interneuron subtype identity by the Iroquois homeobox gene Irx6

(2012) E. N. Star et al.   DEVELOPMENT

Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module

(2012) Matthew Koss et al.   DEVELOPMENTAL CELL

Extradenticle and Homothorax Control Adult Muscle Fiber Identity in Drosophila

(2012) Anton L. Bryantsev et al.   DEVELOPMENTAL CELL

Characterization ofTALEgenes expression during the first lineage segregation in mammalian embryos

(2012) Wendy Sonnet et al.   DEVELOPMENTAL DYNAMICS

Premature Senescence and Increased TGFβ Signaling in the Absence of Tgif1

(2012) Brad J. Zerlanko et al.   PLoS One

Loss of Tgif Function Causes Holoprosencephaly by Disrupting the Shh Signaling Pathway

(2012) Kenichiro Taniguchi et al.   PLoS Genetics

Hox genes define distinct progenitor sub-domains within the second heart field

(2011) Nicolas Bertrand et al.   DEVELOPMENTAL BIOLOGY

A Conserved Pbx-Wnt-p63-Irf6 Regulatory Module Controls Face Morphogenesis by Promoting Epithelial Apoptosis

(2011) Elisabetta Ferretti et al.   DEVELOPMENTAL CELL

Pbx homeodomain proteins: TALEnted regulators of limb patterning and outgrowth

(2011) Terence D. Capellini et al.   DEVELOPMENTAL DYNAMICS

Pancreas organogenesis: From bud to plexus to gland

(2011) Fong Cheng Pan et al.   DEVELOPMENTAL DYNAMICS

Cardiovascular defects in a mouse model of HOXA1 syndrome

(2011) N. Makki et al.   HUMAN MOLECULAR GENETICS

Hox10 Genes Function in Kidney Development in the Differentiation and Integration of the Cortical Stroma

(2011) Alisha R. Yallowitz et al.   PLoS One

Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network

(2011) S.-S. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PBX1 Genomic Pioneer Function Drives ERα Signaling Underlying Progression in Breast Cancer

(2011) Luca Magnani et al.   PLoS Genetics

Epigenetic control of Hox genes during neurogenesis, development, and disease

(2010) Benjamin A. Barber et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

The role ofCdxgenes in the gut and in axial development

(2010) Felix Beck et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The absence of Prep1 causes p53-dependent apoptosis of mouse pluripotent epiblast cells

(2010) L. C. Fernandez-Diaz et al.   DEVELOPMENT

HoxA3 is an apical regulator of haemogenic endothelium

(2010) Michelina Iacovino et al.   NATURE CELL BIOLOGY

Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation

(2009) Shannon E. Powers et al.   DEVELOPMENT

Epigenetic reprogramming and induced pluripotency

(2009) K. Hochedlinger et al.   DEVELOPMENT

The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx

(2009) Elisa Rodríguez-Seguel et al.   DEVELOPMENTAL BIOLOGY

Pbx acts with Hand2 in early myocardial differentiation

(2009) Lisa Maves et al.   DEVELOPMENTAL BIOLOGY

Establishment of Intestinal Identity and Epithelial-Mesenchymal Signaling by Cdx2

(2009) Nan Gao et al.   DEVELOPMENTAL CELL

Identification of hoxb1b downstream genes: hoxb1b as a regulatory factor controlling transcriptional networks and cell movement during zebrafish gastrulation

(2009) Willem M.R. van den Akker et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Forcing cells to change lineages

(2009) Thomas Graf et al.   NATURE

KLF4 and PBX1 Directly RegulateNANOGExpression in Human Embryonic Stem Cells

(2009) Ken Kwok-Keung Chan et al.   STEM CELLS

Regeneration, repair and remembering identity: the three Rs of Hox gene expression

(2009) Kevin C. Wang et al.   TRENDS IN CELL BIOLOGY

The clinical spectrum of homozygousHOXA1 mutations

(2008) Thomas M. Bosley et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Pbx/Meis Deficiencies Demonstrate Multigenetic Origins of Congenital Heart Disease

(2008) Kryn Stankunas et al.   CIRCULATION RESEARCH

Evidence for an evolutionary conserved role of homothorax/Meis1/2 during vertebrate retina development

(2008) P. Heine et al.   DEVELOPMENT

Embryonic origin and Hox status determine progenitor cell fate during adult bone regeneration

(2008) P. Leucht et al.   DEVELOPMENT

A dermal HOX transcriptional program regulates site-specific epidermal fate

(2008) J. L. Rinn et al.   GENES & DEVELOPMENT

Hoxb1 Controls Cell Fate Specification and Proliferative Capacity of Neural Stem and Progenitor Cells

(2008) Mina Gouti et al.   STEM CELLS

Mesenchymal Stem Cells from Different Organs are Characterized by Distinct Topographic Hox Codes

(2008) Karin B. Ackema et al.   STEM CELLS AND DEVELOPMENT

The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm

(2007) F. M. Spagnoli et al.   DEVELOPMENT