Loss of Tgif Function Causes Holoprosencephaly by Disrupting the Shh Signaling Pathway

Analysis of genotype-phenotype correlations in human holoprosencephaly

(2010) Benjamin D. Solomon et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Tgif1 represses apolipoprotein gene expression in liver

(2010) Tiffany A. Melhuish et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Zebrafish zic2a patterns the forebrain through modulation of Hedgehog-activated gene expression

(2009) N. A. Sanek et al.   DEVELOPMENT

Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation

(2009) Shannon E. Powers et al.   DEVELOPMENT

Pathogenesis of holoprosencephaly

(2009) Xin Geng et al.   JOURNAL OF CLINICAL INVESTIGATION

Reduced NODAL Signaling Strength via Mutation of Several Pathway Members Including FOXH1 Is Linked to Human Heart Defects and Holoprosencephaly

(2008) Erich Roessler et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Frequency of holoprosencephaly in the International Clearinghouse Birth Defects Surveillance Systems: Searching for population variations

(2008) Emanuele Leoncini et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Gli3 coordinates three-dimensional patterning and growth of the tectum and cerebellum by integrating Shh and Fgf8 signaling

(2008) S. Blaess et al.   DEVELOPMENT

Maternal Tgif is required for vascularization of the embryonic placenta

(2008) Laurent Bartholin et al.   DEVELOPMENTAL BIOLOGY

Mouse Shh is required for prechordal plate maintenance during brain and craniofacial morphogenesis

(2008) Kazushi Aoto et al.   DEVELOPMENTAL BIOLOGY

Haploinsufficiency of Six3 Fails to Activate Sonic hedgehog Expression in the Ventral Forebrain and Causes Holoprosencephaly

(2008) Xin Geng et al.   DEVELOPMENTAL CELL

Genome-Wide Identification of Smad/Foxh1 Targets Reveals a Role for Foxh1 in Retinoic Acid Regulation and Forebrain Development

(2008) Cristoforo Silvestri et al.   DEVELOPMENTAL CELL

Zic2 -associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation

(2008) Nicholas Warr et al.   HUMAN MOLECULAR GENETICS

Regulation of a remote Shh forebrain enhancer by the Six3 homeoprotein

(2008) Yongsu Jeong et al.   NATURE GENETICS

The genetics of early telencephalon patterning: some assembly required

(2008) Jean M. Hébert et al.   NATURE REVIEWS NEUROSCIENCE