Folate and DNA Methylation: A Review of Molecular Mechanisms and the Evidence for Folate's Role

Fortification of Flour with Folic Acid

(2015) Robert J. Berry et al.   FOOD AND NUTRITION BULLETIN

Epigenomic Analysis of Aberrantly Methylated Genes in Colorectal Cancer Identifies Genes Commonly Affected by Epigenetic Alterations

(2011) Young-Ho Kim et al.   ANNALS OF SURGICAL ONCOLOGY

Prenatal Famine and Adult Health

(2011) L.H. Lumey et al.   Annual Review of Public Health

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

(2011) Junjie U. Guo et al.   CELL

Prolonged Exposure to Particulate Pollution, Genes Associated with Glutathione Pathways, and DNA Methylation in a Cohort of Older Men

(2011) Jaime Madrigano et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Gestational low protein diet in the rat mediatesIgf2gene expression in male offspring via altered hepatic DNA methylation

(2011) Li Gong et al.   Epigenetics

Comparison of methyl-DNA immunoprecipitation (MeDIP) and methyl-CpG binding domain (MBD) protein capture for genome-wide DNA methylation analysis reveal CpG sequence coverage bias

(2011) Shalima S. Nair et al.   Epigenetics

Methylation variation atIGF2differentially methylated regions and maternal folic acid use before and during pregnancy

(2011) Cathrine Hoyo et al.   Epigenetics

Global methylation profiles in DNA from different blood cell types

(2011) Hui-Chen Wu et al.   Epigenetics

Relationship of folate, vitamin B12 and methylation of insulin-like growth factor-II in maternal and cord blood

(2011) Y Ba et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Tet proteins in the limelight

(2011) Nathalie Véron et al.   NATURE

Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling

(2011) Hongcang Gu et al.   Nature Protocols

A higher degree of LINE-1 methylation in peripheral blood mononuclear cells, a one-carbon nutrient related epigenetic alteration, is associated with a lower risk of developing cervical intraepithelial neoplasia

(2011) Chandrika J. Piyathilake et al.   NUTRITION

Expanded methyl-sensitive cut counting reveals hypomethylation as an epigenetic state that highlights functional sequences of the genome

(2011) A. Colaneri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of imprinted genes in humans

(2011) Gudrun Moore et al.   GENOME BIOLOGY

Genome-wide assessment of imprinted expression in human cells

(2011) Lisanne Morcos et al.   GENOME BIOLOGY

Unmetabolized serum folic acid and its relation to folic acid intake from diet and supplements in a nationally representative sample of adults aged ≥60 y in the United States

(2010) Regan L Bailey et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Global DNA methylation measurement by HPLC using low amounts of DNA

(2010) Kelly M. Armstrong et al.   Biotechnology Journal

Repetitive element hypomethylation in blood leukocyte DNA and cancer incidence, prevalence, and mortality in elderly individuals: the Normative Aging Study

(2010) Zhong-Zheng Zhu et al.   CANCER CAUSES & CONTROL

Association between Folate Levels and CpG Island Hypermethylation in Normal Colorectal Mucosa

(2010) K. Wallace et al.   Cancer Prevention Research

Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals

(2010) Benjamin R. Carone et al.   CELL

Distinct Epigenomic Landscapes of Pluripotent and Lineage-Committed Human Cells

(2010) R. David Hawkins et al.   Cell Stem Cell

Epigenetic Transitions in Germ Cell Development and Meiosis

(2010) Satya K. Kota et al.   DEVELOPMENTAL CELL

Early environmental effects on epigenetic regulation in humans

(2010) Robert A. Waterland   Epigenetics

LINE-1 DNA methylation is inversely correlated with cord plasma homocysteine in man: A preliminary study

(2010) Anthony A. Fryer et al.   Epigenetics

Genomic imprinting and human disease

(2010) Ryutaro Hirasawa et al.   Essays in Biochemistry

Genomic imprinting mechanisms in embryonic and extraembryonic mouse tissues

(2010) Q J Hudson et al.   HEREDITY

Choline Intake Exceeding Current Dietary Recommendations Preserves Markers of Cellular Methylation in a Genetic Subgroup of Folate-Compromised Men

(2010) William Shin et al.   JOURNAL OF NUTRITION

Comprehensive methylome map of lineage commitment from haematopoietic progenitors

(2010) Hong Ji et al.   NATURE

Relationship between nucleosome positioning and DNA methylation

(2010) Ramakrishna K. Chodavarapu et al.   NATURE

Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

(2010) Sheau-Fang Ng et al.   NATURE

Conserved role of intragenic DNA methylation in regulating alternative promoters

(2010) Alika K. Maunakea et al.   NATURE

Epigenetic modifications as therapeutic targets

(2010) Theresa K Kelly et al.   NATURE BIOTECHNOLOGY

Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications

(2010) R Alan Harris et al.   NATURE BIOTECHNOLOGY

Active DNA demethylation: many roads lead to Rome

(2010) Susan C. Wu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sex-Specific Parent-of-Origin Allelic Expression in the Mouse Brain

(2010) C. Gregg et al.   SCIENCE

Dnmt3a-Dependent Nonpromoter DNA Methylation Facilitates Transcription of Neurogenic Genes

(2010) H. Wu et al.   SCIENCE

Epigenetic Reprogramming in Plant and Animal Development

(2010) Suhua Feng et al.   SCIENCE

Targeting DNA methylation for epigenetic therapy

(2010) Xiaojing Yang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Breast Cancer DNA Methylation Profiles Are Associated with Tumor Size and Alcohol and Folate Intake

(2010) Brock C. Christensen et al.   PLoS Genetics

Season of Conception in Rural Gambia Affects DNA Methylation at Putative Human Metastable Epialleles

(2010) Robert A. Waterland et al.   PLoS Genetics

Lipid profiles in middle-aged men and women after famine exposure during gestation: the Dutch Hunger Winter Families Study

(2009) LH Lumey et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Role of chromatin states in transcriptional memory

(2009) Sharmistha Kundu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Epigenetics in cancer

(2009) S. Sharma et al.   CARCINOGENESIS

CpG islands - ‘A rough guide’

(2009) Robert S. Illingworth et al.   FEBS LETTERS

Epigenomic profiling indicates a role for DNA methylation in early postnatal liver development

(2009) Robert A. Waterland et al.   HUMAN MOLECULAR GENETICS

DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific

(2009) Elmar W. Tobi et al.   HUMAN MOLECULAR GENETICS

Changes in DNA methylation of tandem DNA repeats are different from interspersed repeats in cancer

(2009) Si Ho Choi et al.   INTERNATIONAL JOURNAL OF CANCER

Epigenetic asymmetry in the zygote and mammalian development

(2009) Robert Feil   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

One-Carbon Metabolism–Genome Interactions in Folate-Associated Pathologies

(2009) Patrick J. Stover   JOURNAL OF NUTRITION

Imprinting evolution and human health

(2009) Radhika Das et al.   MAMMALIAN GENOME

CpG island methylation profiling in human melanoma cell lines

(2009) Carmen S. Tellez et al.   MELANOMA RESEARCH

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

(2009) Madeleine P Ball et al.   NATURE BIOTECHNOLOGY

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

(2009) Rafael A Irizarry et al.   NATURE GENETICS

Rethinking how DNA methylation patterns are maintained

(2009) Peter A. Jones et al.   NATURE REVIEWS GENETICS

Developmental programming of CpG island methylation profiles in the human genome

(2009) Ravid Straussman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Periconceptional Maternal Folic Acid Use of 400 µg per Day Is Related to Increased Methylation of the IGF2 Gene in the Very Young Child

(2009) Régine P. Steegers-Theunissen et al.   PLoS One

Neuronal Activity-Induced Gadd45b Promotes Epigenetic DNA Demethylation and Adult Neurogenesis

(2009) D. K. Ma et al.   SCIENCE

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

Developmental Origins of Health and Disease: Environmental Exposures

(2009) James Swanson et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Developmental Origins of Health and Disease: Brief History of the Approach and Current Focus on Epigenetic Mechanisms

(2009) Pathik Wadhwa et al.   SEMINARS IN REPRODUCTIVE MEDICINE

DNA demethylation by DNA repair

(2009) Mary Gehring et al.   TRENDS IN GENETICS

X Chromosome Dosage Compensation: How Mammals Keep the Balance

(2008) Bernhard Payer et al.   Annual Review of Genetics

Folic Acid Supplementation and Cancer Risk: Point

(2008) Y.-I. Kim   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Epigenetic mechanisms in mammals

(2008) J. K. Kim et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Comprehensive high-throughput arrays for relative methylation (CHARM)

(2008) R. A. Irizarry et al.   GENOME RESEARCH

A fingerprint marker from early gestation associated with diabetes in middle age: The Dutch Hunger Winter Families Study

(2008) H. S Kahn et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case–control study

(2008) Lee E Moore et al.   LANCET ONCOLOGY

Decline in genomic DNA methylation through aging in a cohort of elderly subjects

(2008) Valentina Bollati et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The MBD protein family—Reading an epigenetic mark?

(2008) Archana Dhasarathy et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Epigenetic events in mammalian germ-cell development: reprogramming and beyond

(2008) Hiroyuki Sasaki et al.   NATURE REVIEWS GENETICS

DNA methylation landscapes: provocative insights from epigenomics

(2008) Miho M. Suzuki et al.   NATURE REVIEWS GENETICS

Persistent epigenetic differences associated with prenatal exposure to famine in humans

(2008) B. T. Heijmans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GADD45A Does Not Promote DNA Demethylation

(2008) Seung-Gi Jin et al.   PLoS Genetics