Evaluation of arene ruthenium(ii) N-heterocyclic carbene complexes as organometallics interacting with thiol and selenol containing biomolecules

Designing organometallic compounds for catalysis and therapy

(2012) Anna Louisa Noffke et al.   CHEMICAL COMMUNICATIONS

Anticancer Activity of Silver-N-Heterocyclic Carbene Complexes: Caspase-Independent Induction of Apoptosis via Mitochondrial Apoptosis-Inducing Factor (AIF)

(2012) Laure Eloy et al.   ChemMedChem

Anthracene-Tethered Ruthenium(II) Arene Complexes as Tools To Visualize the Cellular Localization of Putative Organometallic Anticancer Compounds

(2012) Alexey A. Nazarov et al.   INORGANIC CHEMISTRY

Highly active neutral ruthenium(II) arene complexes: Synthesis, characterization, and investigation of their anticancer properties

(2012) Gerd Ludwig et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Synthesis, Characterization, and in Vitro Studies of Bis[1,3-diethyl-4,5-diarylimidazol-2-ylidene]gold(I/III) Complexes

(2012) Wukun Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Gold(I) Carbene Complexes Causing Thioredoxin 1 and Thioredoxin 2 Oxidation as Potential Anticancer Agents

(2012) Esther Schuh et al.   JOURNAL OF MEDICINAL CHEMISTRY

A spontaneous gold(i)-azide alkyne cycloaddition reaction yields gold-peptide bioconjugates which overcome cisplatin resistance in a p53-mutant cancer cell line

(2012) S. David Köster et al.   Chemical Science

From Catalysts to Bioactive Organometallics: Do Grubbs Catalysts Trigger Biological Effects?

(2011) Luciano Oehninger et al.   ChemMedChem

Ruthenium anticancer compounds: myths and realities of the emerging metal-based drugs

(2011) Alberta Bergamo et al.   DALTON TRANSACTIONS

Evaluation of reproductive toxicity in male rats treated with novel synthesized ruthenium(II) and gold(I)-NHC complexes

(2011) Osman Ciftci et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Biomolecule binding vs. anticancer activity: Reactions of Ru(arene)[(thio)pyr-(id)one] compounds with amino acids and proteins

(2011) Samuel M. Meier et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Comparative in Vitro Evaluation of N-Heterocyclic Carbene Gold(I) Complexes of the Benzimidazolylidene Type

(2011) Riccardo Rubbiani et al.   JOURNAL OF MEDICINAL CHEMISTRY

Organometallic Ruthenium(II) Arene Compounds with Antiangiogenic Activity

(2011) Patrycja Nowak-Sliwinska et al.   JOURNAL OF MEDICINAL CHEMISTRY

Organometallic peptide NHC complexes of Cp∗Rh(III) and arene Ru(II) moieties from l-thiazolylalanine

(2011) Jessica Lemke et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Advances in metal–carbene complexes as potent anti-cancer agents

(2011) Arnaud Gautier et al.   Metallomics

Real-Time Monitoring of Cisplatin-Induced Cell Death

(2011) Hamed Alborzinia et al.   PLoS One

The determination of oxidative damage in heart tissue of rats caused by ruthenium(II) and gold(I) N-heterocyclic carbene complexes

(2011) Osman Ciftci et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Synthesis, Cytotoxicity and Antibacterial Studies of Novel Symmetrically and Non-Symmetrically p-Nitrobenzyl-Substituted N-Heterocyclic Carbene-Silver(I) Acetate Complexes

(2011) Siddappa Patil et al.   ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE

Fascinating frontiers of N/O-functionalized N-heterocyclic carbene chemistry: from chemical catalysis to biomedical applications

(2010) Alex John et al.   DALTON TRANSACTIONS

Benzimidazol-2-ylidene Gold(I) Complexes Are Thioredoxin Reductase Inhibitors with Multiple Antitumor Properties

(2010) Riccardo Rubbiani et al.   JOURNAL OF MEDICINAL CHEMISTRY

Organometallic Anticancer Compounds

(2010) Gilles Gasser et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and anticancer properties of gold(I) and silver(I) N-heterocyclic carbene complexes

(2010) Tammy J. Siciliano et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Organometallic ruthenium-based antitumor compounds with novel modes of action

(2010) Wee Han Ang et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Novel benzyl-substituted N-heterocyclic carbene–silver acetate complexes: synthesis, cytotoxicity and antibacterial studies

(2010) Siddappa Patil et al.   Metallomics

Biomedical Properties of a Series of Ruthenium-N-Heterocyclic Carbene Complexes Based on Oxidant Activity In Vitro and Assessment In Vivo of Biosafety in Zebrafish Embryos

(2010) Juan M. Alfaro et al.   Zebrafish

Synthesis, structural characterisation and anti-proliferative activity of NHC gold amino acid and peptide conjugates

(2009) Jessica Lemke et al.   DALTON TRANSACTIONS

Metal-NHC complexes: a survey of anti-cancer properties

(2009) Marie-Laure Teyssot et al.   DALTON TRANSACTIONS

Heterocyclic Carbenes: Synthesis and Coordination Chemistry

(2008) F. Ekkehardt Hahn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Synthesis of Ruthenium and Rhodium Complexes with Functionalized N‐Heterocyclic Carbenes and Their Use in Solid Phase Peptide Synthesis

(2008) Jessica Lemke et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Hydrolysis study of the bifunctional antitumour compound RAPTA-C, [Ru(η6-p-cymene)Cl2(pta)]

(2008) Claudine Scolaro et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Emerging Protein Targets for Anticancer Metallodrugs: Inhibition of Thioredoxin Reductase and Cathepsin B by Antitumor Ruthenium(II)−Arene Compounds

(2008) Angela Casini et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mitochondria-Targeted Chemotherapeutics: The Rational Design of Gold(I)N-Heterocyclic Carbene Complexes That Are Selectively Toxic to Cancer Cells and Target Protein Selenols in Preference to Thiols

(2008) James L. Hickey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Analyses of Titanocenes in the spheroid-based cellular angiogenesis assay

(2007) Holger Weber et al.   TOXICOLOGY IN VITRO