Ruthenium anticancer compounds: myths and realities of the emerging metal-based drugs

Phase II trial of gemcitabine plus cisplatin in patients with advanced non-small cell lung cancer

(2010) Yun Fan et al.   ACTA PHARMACOLOGICA SINICA

Modulation of cell sensitivity to antitumor agents by targeting survival pathways

(2010) Paola Perego et al.   BIOCHEMICAL PHARMACOLOGY

Ruthenium-based chemotherapeutics: are they ready for prime time?

(2010) Emmanuel S. Antonarakis et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Phase I/II and Pharmacokinetic Study of Intravenous Vinflunine in Combination With Cisplatin for the Treatment of Chemonaive Patients With Advanced Non–Small-Cell Lung Cancer

(2010) Pierre-Jean Souquet et al.   Clinical Lung Cancer

A phase II study of pemetrexed and carboplatin as a salvage therapy for platinum-pretreated patients with non-small cell lung cancer

(2010) Hyeong Su Kim et al.   LUNG CANCER

New Platinum and Ruthenium Complexes - the Latest Class of Potential Chemotherapeutic Drugs - a Review of Recent Developments in the Field

(2010) Amr Amin et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Targeting anoikis resistance in prostate cancer metastasis

(2010) Shinichi Sakamoto et al.   MOLECULAR ASPECTS OF MEDICINE

EGFR Signaling and Drug Discovery

(2010) Georg Lurje et al.   ONCOLOGY

Inhibition of Bcl-2 and Bcl-X enhances chemotherapy sensitivity in hepatoblastoma cells

(2010) Justus Lieber et al.   PEDIATRIC BLOOD & CANCER

Forcing Cancer Cells to Commit Suicide

(2009) Christel Vangestel et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

A Ruthenium-Containing Organometallic Compound Reduces Tumor Growth through Induction of the Endoplasmic Reticulum Stress Gene CHOP

(2009) Xiangjun Meng et al.   CANCER RESEARCH

Targeting proteins with metal complexes

(2009) Eric Meggers   CHEMICAL COMMUNICATIONS

Satraplatin for the therapy of castration-resistant prostate cancer

(2009) Guru Sonpavde et al.   Future Oncology

Novel ways to sensitise gastrointestinal cancer to apoptosis

(2009) H Schulze-Bergkamen et al.   GUT

Efficacy of taxane and platinum-based chemotherapy guided by extreme drug resistance assay in patients with epithelial ovarian cancer

(2009) Won Deok Joo et al.   Journal of Gynecologic Oncology

In vivo tumour and metastasis reduction and in vitro effects on invasion assays of the ruthenium RM175 and osmium AFAP51 organometallics in the mammary cancer model

(2009) A. Bergamo et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Treatment of advanced non-small-cell lung cancer in the elderly

(2009) Cesare Gridelli et al.   LUNG CANCER

Similar Biological Activities of Two Isostructural Ruthenium and Osmium Complexes

(2008) Jasna Maksimoska et al.   CHEMISTRY-A EUROPEAN JOURNAL

Medicinal Organometallic Chemistry: Designing Metal Arene Complexes as Anticancer Agents

(2008) Anna F. A. Peacock et al.   Chemistry-An Asian Journal

Current Status and Future Prospects for Satraplatin, an Oral Platinum Analogue

(2008) H. Choy et al.   CLINICAL CANCER RESEARCH

The ruthenium(II)–arene compound RAPTA-C induces apoptosis in EAC cells through mitochondrial and p53–JNK pathways

(2008) Soumya Chatterjee et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Targeted manipulation of apoptosis in cancer treatment

(2008) Justin A Call et al.   LANCET ONCOLOGY

Antitumour metal compounds: more than theme and variations

(2007) Michael A. Jakupec et al.   DALTON TRANSACTIONS