Screening organometallic binuclear thiosemicarbazone ruthenium complexes as potential anti-tumour agents: cytotoxic activity and human serum albumin binding mechanism

Challenges and Opportunities in the Development of Organometallic Anticancer Drugs

(2012) Christian G. Hartinger et al.   ORGANOMETALLICS

Targeted and multifunctional arene ruthenium chemotherapeutics

(2011) Gregory S. Smith et al.   DALTON TRANSACTIONS

New organoruthenium complexes with bioactive thiosemicarbazones as co-ligands: potential anti-trypanosomal agents

(2011) Bruno Demoro et al.   DALTON TRANSACTIONS

Mono- and dinuclear (η6-arene) ruthenium(II) benzaldehyde thiosemicarbazone complexes: Synthesis, characterization and cytotoxicity

(2011) Tameryn Stringer et al.   INORGANIC CHEMISTRY COMMUNICATIONS

Half-sandwich ruthenium–arene complexes with thiosemicarbazones: Synthesis and biological evaluation of [(η6-p-cymene)Ru(piperonal thiosemicarbazones)Cl]Cl complexes

(2011) Floyd Beckford et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Copper(II) complexes with tridentate pyrazole-based ligands: synthesis, characterization, DNA cleavage activity and cytotoxicity

(2011) Sofia Gama et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Approaching tumour therapy beyond platinum drugs

(2011) A. Bergamo et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Mitosis as an anti-cancer target

(2011) A Janssen et al.   ONCOGENE

Tumor-Selective Delivery of Macromolecular Drugs via the EPR Effect: Background and Future Prospects

(2010) Hiroshi Maeda   BIOCONJUGATE CHEMISTRY

Studies of the Antiproliferative Activity of Ruthenium (II) Cyclopentadienyl-Derived Complexes with Nitrogen Coordinated Ligands

(2010) Virtudes Moreno et al.   BIOINORGANIC CHEMISTRY AND APPLICATIONS

Ruthenium-based chemotherapeutics: are they ready for prime time?

(2010) Emmanuel S. Antonarakis et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Transport of Therapeutic Vanadium and Ruthenium Complexes by Blood Plasma Components

(2010) J. Costa Pessoa et al.   CURRENT MEDICINAL CHEMISTRY

Thiophenolato-bridged dinuclear arene ruthenium complexes: a new family of highly cytotoxic anticancer agents

(2010) Michaël Gras et al.   DALTON TRANSACTIONS

Metal-based drugs for malaria, trypanosomiasis and leishmaniasis: recent achievements and perspectives

(2010) Maribel Navarro et al.   DRUG DISCOVERY TODAY

DNA interaction and cytotoxicity studies of new ruthenium(II) cyclopentadienyl derivative complexes containing heteroaromatic ligands

(2010) Virtudes Moreno et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Complexes between Fluorescent Cholic Acid Derivatives and Human Serum Albumin. A Photophysical Approach To Investigate the Binding Behavior

(2010) Jana Rohacova et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Integrins as therapeutic targets: lessons and opportunities

(2010) Dermot Cox et al.   NATURE REVIEWS DRUG DISCOVERY

Microtubule-binding agents: a dynamic field of cancer therapeutics

(2010) Charles Dumontet et al.   NATURE REVIEWS DRUG DISCOVERY

Ligand-independent activation of c-Met by fibronectin and α5β1-integrin regulates ovarian cancer invasion and metastasis

(2010) A K Mitra et al.   ONCOGENE

Arene Control over Thiolate to Sulfinate Oxidation in Albumin by Organometallic Ruthenium Anticancer Complexes

(2009) Wenbing Hu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Areneruthenium complexes as anticancer agents

(2009) Georg Süss-Fink   DALTON TRANSACTIONS

Effect of ruthenium complexation on trypanocidal activity of 5-nitrofuryl containing thiosemicarbazones

(2009) Mariana Pagano et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

5-Nitro-2-furyl derivative actives against Trypanosoma cruzi: Preliminary in vivo studies

(2009) Eliana Cabrera et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Organometallic ruthenium complexes with thiosemicarbazone ligands: Synthesis, structure and cytotoxicity of [(η6-p-cymene)Ru(NS)Cl]+ (NS=9-anthraldehyde thiosemicarbazones)

(2009) Floyd A. Beckford et al.   INORGANIC CHEMISTRY COMMUNICATIONS

Inhibition of cancer cell growth by ruthenium(II) cyclopentadienyl derivative complexes with heteroaromatic ligands

(2009) M. Helena Garcia et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

In vivo tumour and metastasis reduction and in vitro effects on invasion assays of the ruthenium RM175 and osmium AFAP51 organometallics in the mammary cancer model

(2009) A. Bergamo et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Toward the Development of a Potent and Selective Organoruthenium Mammalian Sterile 20 Kinase Inhibitor

(2009) Ruchi Anand et al.   JOURNAL OF MEDICINAL CHEMISTRY

Recent developments in ruthenium anticancer drugs

(2009) Aviva Levina et al.   Metallomics

FRET analysis of domain formation and properties in complex membrane systems

(2008) Luís M.S. Loura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients

(2008) Christian G. Hartinger et al.   CHEMISTRY & BIODIVERSITY

In Vitro Anticancer Activity and Biologically Relevant Metabolization of Organometallic Ruthenium Complexes with Carbohydrate-Based Ligands

(2008) Isabella Berger et al.   CHEMISTRY-A EUROPEAN JOURNAL

New trends for metal complexes with anticancer activity

(2008) Pieter CA Bruijnincx et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Selective Cytotoxic Ru(II) Arene Cp* Complex Salts [R-PhRuCp*]+X−for X = BF4−, PF6−, and BPh4−

(2008) Bradley T. Loughrey et al.   INORGANIC CHEMISTRY

Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles

(2008) Felix Kratz   JOURNAL OF CONTROLLED RELEASE

Platinum(II) metal complexes as potential anti-Trypanosoma cruzi agents

(2007) Marisol Vieites et al.   JOURNAL OF INORGANIC BIOCHEMISTRY