Improved antibody production in Chinese hamster ovary cells by ATF4 overexpression

Rapid construction of transgene-amplified CHO cell lines by cell cycle checkpoint engineering

(2013) Kyoung Ho Lee et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

CHO cell engineering to prevent polypeptide aggregation and improve therapeutic protein secretion

(2013) Valérie Le Fourn et al.   METABOLIC ENGINEERING

Overexpression of CHOP alone and in combination with chaperones is effective in improving antibody production in mammalian cells

(2012) Daisuke Nishimiya et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Recent advances in technology supporting biopharmaceutical production from mammalian cells

(2012) M. Butler et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Optimized signal peptides for the development of high expressing CHO cell lines

(2012) Lars Kober et al.   BIOTECHNOLOGY AND BIOENGINEERING

Metabolic engineering of recombinant protein secretion by Saccharomyces cerevisiae

(2012) Jin Hou et al.   FEMS YEAST RESEARCH

The impact of glycosylation on monoclonal antibody conformation and stability

(2012) Kai Zheng et al.   mAbs

Enhancement of sialylation on humanized IgG-like bispecific antibody by overexpression of α2,6-sialyltransferase derived from Chinese hamster ovary cells

(2011) Masayoshi Onitsuka et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Cell line-specific control of recombinant monoclonal antibody production by CHO cells

(2010) Peter M. O'Callaghan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Maximizing productivity of CHO cell-based fed-batch culture using chemically defined media conditions and typical manufacturing equipment

(2010) Yao-Ming Huang et al.   BIOTECHNOLOGY PROGRESS

Cell Engineering and Cultivation of Chinese Hamster Ovary (CHO) Cells

(2010) Takeshi Omasa et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Oxidative Folding: Cellular Strategies for Dealing with the Resultant Equimolar Production of Reactive Oxygen Species

(2009) Yuichiro Shimizu et al.   ANTIOXIDANTS & REDOX SIGNALING

Glycosylation pattern of humanized IgG-like bispecific antibody produced by recombinant CHO cells

(2009) Wook-Dong Kim et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Identification and analysis of specific chromosomal region adjacent to exogenous Dhfr-amplified region in Chinese hamster ovary cell genome

(2009) Joon Young Park et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

An Unfolded CH1 Domain Controls the Assembly and Secretion of IgG Antibodies

(2009) Matthias J. Feige et al.   MOLECULAR CELL

How antibodies fold

(2009) Matthias J. Feige et al.   TRENDS IN BIOCHEMICAL SCIENCES

A decrease in cellular energy status stimulates PERK-dependent eIF2α phosphorylation and regulates protein synthesis in pancreatic β-cells

(2008) Edith Gomez et al.   BIOCHEMICAL JOURNAL

Engineering of chaperone systems and of the unfolded protein response

(2008) Saeed U. Khan et al.   CYTOTECHNOLOGY

Overexpression of GADD34 Enhances Production of Recombinant Human Antithrombin III in Chinese Hamster Ovary Cells

(2008) Takeshi Omasa et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

ATF4 is an oxidative stress–inducible, prodeath transcription factor in neurons in vitro and in vivo

(2008) Philipp S. Lange et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Diabody-based Recombinant Formats of Humanized IgG-like Bispecific Antibody With Effective Retargeting of Lymphocytes to Tumor Cells

(2008) Ryutaro Asano et al.   JOURNAL OF IMMUNOTHERAPY

Improved production of recombinant human antithrombin III in Chinese hamster ovary cells by ATF4 overexpression

(2007) Tomoshi Ohya et al.   BIOTECHNOLOGY AND BIOENGINEERING