Non-muscle myosins in tumor progression, cancer cell invasion, and metastasis

Targeting invadopodia to block breast cancer metastasis

(2015) Mark A Eckert et al.   Oncotarget

Elevated expression of myosin X in tumours contributes to breast cancer aggressiveness and metastasis

(2014) R Cao et al.   BRITISH JOURNAL OF CANCER

DNA Damage Triggers Golgi Dispersal via DNA-PK and GOLPH3

(2014) Suzette E. Farber-Katz et al.   CELL

Myosin 1e is a component of the invadosome core that contributes to regulation of invadosome dynamics

(2014) Jessica L. Ouderkirk et al.   EXPERIMENTAL CELL RESEARCH

Mutant p53–associated myosin-X upregulation promotes breast cancer invasion and metastasis

(2014) Antti Arjonen et al.   JOURNAL OF CLINICAL INVESTIGATION

Direct in Vivo RNAi Screen Unveils Myosin IIa as a Tumor Suppressor of Squamous Cell Carcinomas

(2014) D. Schramek et al.   SCIENCE

Myosin II in mechanotransduction: master and commander of cell migration, morphogenesis, and cancer

(2013) Rocío Aguilar-Cuenca et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Physical break-down of the classical view on cancer cell invasion and metastasis

(2013) Claudia T. Mierke   EUROPEAN JOURNAL OF CELL BIOLOGY

Functional Characterization of Human Myosin-18A and Its Interaction with F-actin and GOLPH3

(2013) Manuel H. Taft et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functions of Class V Myosins in Neurons

(2013) John A. Hammer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of Three Full-length Human Nonmuscle Myosin II Paralogs

(2013) Neil Billington et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytoskeletal tropomyosins: choreographers of actin filament functional diversity

(2013) Howard Vindin et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Myosin-1c regulates the dynamic stability of E-cadherin–based cell–cell contacts in polarized Madin–Darby canine kidney cells

(2013) Hiroshi Tokuo et al.   MOLECULAR BIOLOGY OF THE CELL

The regulation and functional impact of actin assembly at cadherin cell–cell adhesions

(2013) Magdalene Michael et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Telomerase at the intersection of cancer and aging

(2013) Bruno Bernardes de Jesus et al.   TRENDS IN GENETICS

A myosin-Va tail fragment sequesters dynein light chains leading to apoptosis in melanoma cells

(2013) T C Izidoro-Toledo et al.   Cell Death & Disease

The myosin motor Myo1c is required for VEGFR2 delivery to the cell surface and for angiogenic signaling

(2012) Ajit Tiwari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The many different cellular functions of MYO7A in the retina: Figure 1

(2012) David S. Williams et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Distinct and redundant roles of the non-muscle myosin II isoforms and functional domains

(2012) Aibing Wang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Myosin-IXA Regulates Collective Epithelial Cell Migration by Targeting RhoGAP Activity to Cell-Cell Junctions

(2012) Tatiana Omelchenko et al.   CURRENT BIOLOGY

Invadopodia: The leading force

(2012) Hadas Sibony-Benyamini et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Proteomic analysis of podosome fractions from macrophages reveals similarities to spreading initiation centres

(2012) Pasquale Cervero et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Small-molecule inhibitors of myosin proteins

(2012) Lisa M Bond et al.   Future Medicinal Chemistry

Brush border myosin Ia inactivation in gastric but not endometrial tumors

(2012) Rocco Mazzolini et al.   INTERNATIONAL JOURNAL OF CANCER

Myosin-1A Targets to Microvilli Using Multiple Membrane Binding Motifs in the Tail Homology 1 (TH1) Domain

(2012) Jessica N. Mazerik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The myosin superfamily at a glance

(2012) M. A. Hartman et al.   JOURNAL OF CELL SCIENCE

Myosin 1E coordinates actin assembly and cargo trafficking during clathrin-mediated endocytosis

(2012) Jackie Cheng et al.   MOLECULAR BIOLOGY OF THE CELL

A role for myosin IXb, a motor–RhoGAP chimera, in epithelial wound healing and tight junction regulation

(2012) Surjit K. Chandhoke et al.   MOLECULAR BIOLOGY OF THE CELL

Direct inhibition of myosin II effectively blocks glioma invasion in the presence of multiple motogens

(2012) Sanja Ivkovic et al.   MOLECULAR BIOLOGY OF THE CELL

Classifying collective cancer cell invasion

(2012) Peter Friedl et al.   NATURE CELL BIOLOGY

Brush border Myosin Ia has tumor suppressor activity in the intestine

(2012) R. Mazzolini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myo9B is associated with an increased risk of Barrett's esophagus and esophageal adenocarcinoma

(2012) Vivianda Menke et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Myosin Ia is Required for CFTR Brush Border Membrane Trafficking and Ion Transport in the Mouse Small Intestine

(2012) Dmitri V. Kravtsov et al.   TRAFFIC

Regulation and control of myosin-I by the motor and light chain-binding domains

(2012) Michael J. Greenberg et al.   TRENDS IN CELL BIOLOGY

The Outgrowth of Micrometastases Is Enabled by the Formation of Filopodium-like Protrusions

(2012) Tsukasa Shibue et al.   Cancer Discovery

A Gene Signature for Predicting Outcome in Patients with Basal-like Breast Cancer

(2012) Robin M. Hallett et al.   Scientific Reports

Degrading Devices: Invadosomes in Proteolytic Cell Invasion

(2011) Stefan Linder et al.   Annual Review of Cell and Developmental Biology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Epithelial cell polarity: a major gatekeeper against cancer?

(2011) C Royer et al.   CELL DEATH AND DIFFERENTIATION

A Molecular Pathway for Myosin II Recruitment to Stress Fibers

(2011) Sari Tojkander et al.   CURRENT BIOLOGY

Inactivation of MYO5B Promotes Invasion and Motility in Gastric Cancer Cells

(2011) Wenjie Dong et al.   DIGESTIVE DISEASES AND SCIENCES

Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins

(2011) Herbert B Schiller et al.   EMBO REPORTS

The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells

(2011) Lara Derycke et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Drosophila melanogasterMyosin-18 Represents a Highly Divergent Motor with Actin Tethering Properties

(2011) Stephanie Guzik-Lendrum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myosin-X: a MyTH-FERM myosin at the tips of filopodia

(2011) M. L. Kerber et al.   JOURNAL OF CELL SCIENCE

Links between mutant p53 and genomic instability

(2011) Walter Hanel et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The myosin family: unconventional roles of actin-dependent molecular motors in immune cells

(2011) José L. Maravillas-Montero et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The t(11;19)(q23;p13) fusing MLL with MYO1F is recurrent in infant acute myeloid leukemias

(2011) Francois P. Duhoux et al.   LEUKEMIA RESEARCH

Shroom2 regulates contractility to control endothelial morphogenesis

(2011) Matthew J. Farber et al.   MOLECULAR BIOLOGY OF THE CELL

Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi network

(2011) Claudia G. Almeida et al.   NATURE CELL BIOLOGY

MYO1EMutations and Childhood Familial Focal Segmental Glomerulosclerosis

(2011) Caterina Mele et al.   NEW ENGLAND JOURNAL OF MEDICINE

Myosin II isoform switching mediates invasiveness after TGF- -induced epithelial-mesenchymal transition

(2011) J. R. Beach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Filopodia and adhesion in cancer cell motility

(2011) Antti Arjonen et al.   Cell Adhesion & Migration

Filopodia initiation

(2011) Changsong Yang et al.   Cell Adhesion & Migration

Myo1e Binds Anionic Phospholipids with High Affinity

(2010) Elizabeth A. Feeser et al.   BIOCHEMISTRY

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Polarity protein alterations in carcinoma: a focus on emerging roles for polarity regulators

(2010) Ling Huang et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Myosin 1G Is an Abundant Class I Myosin in Lymphocytes Whose Localization at the Plasma Membrane Depends on Its Ancient Divergent Pleckstrin Homology (PH) Domain (Myo1PH)

(2010) Genaro Patino-Lopez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia

(2010) Marie Schoumacher et al.   JOURNAL OF CELL BIOLOGY

The Motor Protein Myosin-X Transports VE-Cadherin along Filopodia To Allow the Formation of Early Endothelial Cell-Cell Contacts

(2010) S. Almagro et al.   MOLECULAR AND CELLULAR BIOLOGY

Tropomyosin and Myosin-II Cellular Levels Promote Actomyosin Ring Assembly in Fission Yeast

(2010) Benjamin C. Stark et al.   MOLECULAR BIOLOGY OF THE CELL

A nucleator arms race: cellular control of actin assembly

(2010) Kenneth G. Campellone et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Myosin VI and Optineurin Are Required for Polarized EGFR Delivery and Directed Migration

(2010) Margarita V. Chibalina et al.   TRAFFIC

Leveraging the membrane – cytoskeleton interface with myosin-1

(2010) Russell E. McConnell et al.   TRENDS IN CELL BIOLOGY

GOLPH3 Bridges Phosphatidylinositol-4- Phosphate and Actomyosin to Stretch and Shape the Golgi to Promote Budding

(2009) Holly C. Dippold et al.   CELL

Local Cortical Tension by Myosin II Guides 3D Endothelial Cell Branching

(2009) Robert S. Fischer et al.   CURRENT BIOLOGY

Pigmentation-related genes and their implication in malignant melanoma susceptibility

(2009) Lara P. Fernandez et al.   EXPERIMENTAL DERMATOLOGY

The molecular biology of mixed lineage leukemia

(2009) R. K. Slany   HAEMATOLOGICA

Upregulation of myosin Va by Snail is involved in cancer cell migration and metastasis

(2009) Linxiang Lan et al.   INTERNATIONAL JOURNAL OF CANCER

Identification of MYO18A as a Novel Interacting Partner of the PAK2/βPIX/GIT1 Complex and Its Potential Function in Modulating Epithelial Cell Migration

(2009) Rae-Mann Hsu et al.   MOLECULAR BIOLOGY OF THE CELL

GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer

(2009) Kenneth L. Scott et al.   NATURE

MyosinV controls PTEN function and neuronal cell size

(2009) Michiel T. van Diepen et al.   NATURE CELL BIOLOGY

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Collective cell migration in morphogenesis, regeneration and cancer

(2009) Peter Friedl et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Overexpression of myosin VI in prostate cancer cells enhances PSA and VEGF secretion, but has no effect on endocytosis

(2009) C Puri et al.   ONCOGENE

Colitis-associated cancer: the role of T cells in tumor development

(2009) Maximilian J. Waldner et al.   Seminars in Immunopathology

Unconventional myosins acting unconventionally

(2009) Sarah Woolner et al.   TRENDS IN CELL BIOLOGY

TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use

(2009) M. Olivier et al.   Cold Spring Harbor Perspectives in Biology

Collective Epithelial Migration and Cell Rearrangements Drive Mammary Branching Morphogenesis

(2008) Andrew J. Ewald et al.   DEVELOPMENTAL CELL

AcanthamoebaMyosin IC Colocalizes with Phosphatidylinositol 4,5-Bisphosphate at the Plasma Membrane Due to the High Concentration of Negative Charge

(2008) Hanna Brzeska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Basal-Like Breast Cancer: A Critical Review

(2008) Emad A. Rakha et al.   JOURNAL OF CLINICAL ONCOLOGY

Immune-mediated dormancy: an equilibrium with cancer

(2008) Michele W. L. Teng et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Disruption of Myosin 1e Promotes Podocyte Injury

(2008) M. Krendel et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Role of Myosin II in Glioma Invasion of the Brain

(2008) Christopher Beadle et al.   MOLECULAR BIOLOGY OF THE CELL