Absence of aryl hydrocarbon receptors increases endogenous kynurenic acid levels and protects mouse brain against excitotoxic insult and oxidative stress

Improvement in suicidal ideation after ketamine infusion: Relationship to reductions in depression and anxiety

(2014) Elizabeth D. Ballard et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Improvement of Mitochondrial Function by Paliperidone Attenuates Quinolinic Acid-Induced Behavioural and Neurochemical Alterations in Rats: Implications in Huntington’s Disease

(2014) Jitendriya Mishra et al.   NEUROTOXICITY RESEARCH

Modulation by kynurenine of extracellular kynurenate and glutamate in cerebral cortex of rats with acute liver failure

(2014) Wojciech Hilgier et al.   Pharmacological Reports

Thel-kynurenine-probenecid combination reduces neuropathic pain in rats

(2013) J.B. Pineda-Farias et al.   EUROPEAN JOURNAL OF PAIN

The causative role and therapeutic potential of the kynurenine pathway in neurodegenerative disease

(2013) Marta Amaral et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Early developmental elevations of brain kynurenic acid impair cognitive flexibility in adults: Reversal with galantamine

(2013) K.S. Alexander et al.   NEUROSCIENCE

GPR35 Activation Reduces Ca2+ Transients and Contributes to the Kynurenic Acid-Dependent Reduction of Synaptic Activity at CA3-CA1 Synapses

(2013) Rolando Berlinguer-Palmini et al.   PLoS One

Kynurenic acid: a metabolite with multiple actions and multiple targets in brain and periphery

(2012) Flavio Moroni et al.   JOURNAL OF NEURAL TRANSMISSION

Ammonia upregulates kynurenine aminotransferase II mRNA expression in rat brain: a role for astrocytic NMDA receptors?

(2012) Marta Obara-Michlewska et al.   METABOLIC BRAIN DISEASE

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

Adenoviral Astrocyte-Specific Expression of BDNF in the Striata of Mice Transgenic for Huntington’s Disease Delays the Onset of the Motor Phenotype

(2011) Leticia Arregui et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

(2011) Christiane A. Opitz et al.   NATURE

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

Neuroprotective effects of a novel kynurenic acid analogue in a transgenic mouse model of Huntington’s disease

(2010) Dénes Zádori et al.   JOURNAL OF NEURAL TRANSMISSION

Kynurenic Acid Is a Potent Endogenous Aryl Hydrocarbon Receptor Ligand that Synergistically Induces Interleukin-6 in the Presence of Inflammatory Signaling

(2010) Brett C. DiNatale et al.   TOXICOLOGICAL SCIENCES

Structure, expression, and function of kynurenine aminotransferases in human and rodent brains

(2009) Qian Han et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Knockdown of the aryl hydrocarbon receptor attenuates excitotoxicity and enhances NMDA-induced BDNF expression in cortical neurons

(2009) Chun-Hua Lin et al.   JOURNAL OF NEUROCHEMISTRY

Glutamate toxicity in the striatum of the R6/2 Huntington's disease transgenic mice is age-dependent and correlates with decreased levels of glutamate transporters

(2009) Ana María Estrada-Sánchez et al.   NEUROBIOLOGY OF DISEASE