Inflammatory cytokine receptor blockade in a rodent model of mild traumatic brain injury

Recombinant Human Interleukin-1 Receptor Antagonist in Severe Traumatic Brain Injury: A Phase II Randomized Control Trial

(2014) Adel Helmy et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A rodent model of mild traumatic brain blast injury

(2014) J.R. Perez-Polo et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Studies of selective TNF inhibitors in the treatment of brain injury from stroke and trauma: a review of the evidence to date

(2014) Antonino Tuttolomondo et al.   Drug Design Development and Therapy

Etanercept attenuates traumatic brain injury in rats by reducing early microglial expression of tumor necrosis factor-α

(2013) Chung-Ching Chio et al.   BMC NEUROSCIENCE

Inflammatory Consequences in a Rodent Model of Mild Traumatic Brain Injury

(2013) J. Regino Perez-Polo et al.   JOURNAL OF NEUROTRAUMA

Challenges in the Development of Rodent Models of Mild Traumatic Brain Injury

(2013) Douglas S. DeWitt et al.   JOURNAL OF NEUROTRAUMA

Pharmacokinetics and Brain Uptake of an IgG-TNF Decoy Receptor Fusion Protein Following Intravenous, Intraperitoneal, and Subcutaneous Administration in Mice

(2013) Rachita K. Sumbria et al.   MOLECULAR PHARMACEUTICS

Selective TNF Inhibition for Chronic Stroke and Traumatic Brain Injury

(2012) Edward Tobinick et al.   CNS DRUGS

The cytokine temporal profile in rat cortex after controlled cortical impact

(2012) Clifton L. Dalgard et al.   Frontiers in Molecular Neuroscience

Rapid Improvement of Chronic Stroke Deficits after Perispinal Etanercept

(2011) Edward Tobinick   CNS DRUGS

Implications of Gliotransmission for the Pharmacotherapy of CNS Disorders

(2011) Daniela Rossi et al.   CNS DRUGS

A clinical perspective of IL-1β as the gatekeeper of inflammation

(2011) Charles A. Dinarello   EUROPEAN JOURNAL OF IMMUNOLOGY

Neutralization of interleukin-1β reduces cerebral edema and tissue loss and improves late cognitive outcome following traumatic brain injury in mice

(2011) Fredrik Clausen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Tumor necrosis factor-α synthesis inhibitor, 3,6′-dithiothalidomide, reverses behavioral impairments induced by minimal traumatic brain injury in mice

(2011) Renana Baratz et al.   JOURNAL OF NEUROCHEMISTRY

Developmental regulation of the neuroinflammatory responses to LPS and/or hypoxia-ischemia between preterm and term neonates: An experimental study

(2011) Marie-Elsa Brochu et al.   Journal of Neuroinflammation

Cytokines and innate inflammation in the pathogenesis of human traumatic brain injury

(2011) Adel Helmy et al.   PROGRESS IN NEUROBIOLOGY

Early TBI-Induced Cytokine Alterations are Similarly Detected by Two Distinct Methods of Multiplex Assay

(2011) Sanjib Mukherjee et al.   Frontiers in Molecular Neuroscience

Position Statement: Definition of Traumatic Brain Injury

(2010) David K. Menon et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

The Cytokine Response to Human Traumatic Brain Injury: Temporal Profiles and Evidence for Cerebral Parenchymal Production

(2010) Adel Helmy et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Therapeutic evaluation of etanercept in a model of traumatic brain injury

(2010) Chung-Ching Chio et al.   JOURNAL OF NEUROCHEMISTRY

Craniotomy: True Sham for Traumatic Brain Injury, or a Sham of a Sham?

(2010) Jeffrey T. Cole et al.   JOURNAL OF NEUROTRAUMA

Interleukin-1 (IL-1) Pathway

(2010) A. Weber et al.   Science Signaling

IL-1/IL-1ra balance in the brain revisited – Evidence from transgenic mouse models

(2009) S. Spulber et al.   BRAIN BEHAVIOR AND IMMUNITY

Neutralization of interleukin-1β modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice

(2009) Fredrik Clausen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Systematic Review and Stratified Meta-analysis of the Efficacy of Interleukin-1 Receptor Antagonist in Animal Models of Stroke

(2009) Victoria Banwell et al.   Journal of Stroke & Cerebrovascular Diseases

Inflammatory Cytokines in Acute Ischemic Stroke

(2008) Antonino Tuttolomondo et al.   CURRENT PHARMACEUTICAL DESIGN

Distinct Cellular Patterns of Upregulated Chemokine Expression Supporting a Prominent Inflammatory Role in Traumatic Brain Injury

(2008) Charlotte Israelsson et al.   JOURNAL OF NEUROTRAUMA

Interleukin-1 receptor antagonist attenuates the severity of spinal cord ischemic injury in rabbits

(2008) Satoshi Akuzawa et al.   JOURNAL OF VASCULAR SURGERY

Nuclear factor-κB decoy amelioration of spinal cord injury-induced inflammation and behavior outcomes

(2007) Danny Salah Rafati et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Tumor necrosis factor antagonist mechanisms of action: A comprehensive review

(2007) Daniel Tracey et al.   PHARMACOLOGY & THERAPEUTICS